GB1443439A - Method for separating serum - Google Patents

Method for separating serum

Info

Publication number
GB1443439A
GB1443439A GB3726673A GB3726673A GB1443439A GB 1443439 A GB1443439 A GB 1443439A GB 3726673 A GB3726673 A GB 3726673A GB 3726673 A GB3726673 A GB 3726673A GB 1443439 A GB1443439 A GB 1443439A
Authority
GB
United Kingdom
Prior art keywords
centrifuging
sealant
serum
blood
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3726673A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB1443439A publication Critical patent/GB1443439A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

1443439 Centrifuging blood M J LUKACS and I H JACOBY 6 Aug 1973 37266/73 Heading B2P [Also in Division C3] Whole blood is separated into serum and clot portions by centrifuging it in the presence of a thixotropic, water-insoluble, non-toxic sealant consisting of a liquid organosilicon compound and an inert filler and having a specific gravity of 1.026 to 1.095 until the sealant forms a separating layer between the serum and clot portions. In Examples the filler is silica or a mixture of silicas and the organosilicon liquid is a polydimethylsiloxane or ethyl triethoxysilane. A device containing the sealant for dispersing it into the blood during centrifuging is described and claimed in Specification 1443440.
GB3726673A 1972-07-10 1973-08-06 Method for separating serum Expired GB1443439A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27027872A 1972-07-10 1972-07-10

Publications (1)

Publication Number Publication Date
GB1443439A true GB1443439A (en) 1976-07-21

Family

ID=23030661

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3726673A Expired GB1443439A (en) 1972-07-10 1973-08-06 Method for separating serum

Country Status (4)

Country Link
US (1) US3780935A (en)
CH (1) CH611424A5 (en)
FR (1) FR2240668A5 (en)
GB (1) GB1443439A (en)

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US3919085A (en) * 1974-02-27 1975-11-11 Becton Dickinson Co Plasma separator assembly
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US3957654A (en) * 1974-02-27 1976-05-18 Becton, Dickinson And Company Plasma separator with barrier to eject sealant
US3920549A (en) * 1974-03-18 1975-11-18 Corning Glass Works Method and apparatus for multiphase fluid collection and separation
US3929646A (en) * 1974-07-22 1975-12-30 Technicon Instr Serum separator and fibrin filter
US4189382A (en) * 1974-11-07 1980-02-19 Sherwood Medical Industries Inc. Blood coagulation and separation
US4049692A (en) * 1974-12-16 1977-09-20 Corning Glass Works Stabilized blood separating composition
US3977982A (en) * 1975-01-20 1976-08-31 Corning Glass Works Controlling viscosity of silica-silicone oil gels
US3957653A (en) * 1975-04-03 1976-05-18 Becton, Dickinson And Company Apparatus for collection, separation and isolation of blood
US3986962A (en) * 1975-07-10 1976-10-19 Becton, Dickinson And Company Novel assembly for separating blood
US3976579A (en) * 1975-07-10 1976-08-24 Becton, Dickinson And Company Novel assembly
US4052320A (en) * 1975-08-29 1977-10-04 Eastman Kodak Company Telescoping serum separator and dispenser
US4018564A (en) * 1975-11-24 1977-04-19 General Electric Company Silicone composition for analyzing blood samples
US4021340A (en) * 1975-11-28 1977-05-03 Corning Glass Works Blood separating composition
US4055501A (en) * 1976-01-16 1977-10-25 Sherwood Medical Industries Inc. Fluid collection device with phase partitioning means
US4088582A (en) * 1976-01-16 1978-05-09 Sherwood Medical Industries Inc. Blood phase separation means
JPS587187B2 (en) * 1976-09-29 1983-02-08 日本ペイント株式会社 Serum or plasma separation
US4152269A (en) * 1977-02-01 1979-05-01 Warner-Lambert Company Collection and separation device
US4101422A (en) * 1977-05-11 1978-07-18 Emery Industries, Inc. Copolyesters useful in blood separation assemblies
US4350593A (en) * 1977-12-19 1982-09-21 Becton, Dickinson And Company Assembly, compositions and method for separating blood
US4190535A (en) * 1978-02-27 1980-02-26 Corning Glass Works Means for separating lymphocytes and monocytes from anticoagulated blood
US4333564A (en) * 1978-05-22 1982-06-08 Sherwood Medical Industries Inc. Method of controlling rheological properties of gel-like compositions
US4167955A (en) * 1978-06-05 1979-09-18 Beckman Instruments, Inc. Layering a liquid sample onto centrifuge tube liquid contents
US4235725A (en) * 1978-08-16 1980-11-25 Owens-Illinois, Inc. Sterile blood-collecting and separating device
US4279863A (en) * 1979-09-12 1981-07-21 Sherwood Medical Industries, Inc. Reagent separator for a blood collection tube
DE3165646D1 (en) * 1980-05-08 1984-09-27 Terumo Corp Apparatus for separating blood
US4457782A (en) * 1980-08-18 1984-07-03 Sekisui Kagaku Kogyo Kabushiki Kaisha Composition for partitioning blood components
US4386003A (en) * 1981-09-17 1983-05-31 Sherwood Medical Industries Inc. Blood separating composition
EP0353587A3 (en) * 1988-07-26 1992-07-29 Nippon Paint Co., Ltd. Serum separation sealant and fine resin particles used in the same
US4994393A (en) * 1989-02-22 1991-02-19 Becton, Dickinson And Company Blood partitioning composition
US5266199A (en) * 1990-11-20 1993-11-30 Nigata Chemicals And Plastics Co., Ltd. Serum separating apparatus
US5236604A (en) * 1991-05-29 1993-08-17 Sherwood Medical Company Serum separation blood collection tube and the method of using thereof
US5269927A (en) * 1991-05-29 1993-12-14 Sherwood Medical Company Separation device for use in blood collection tubes
JP3260219B2 (en) * 1992-11-12 2002-02-25 日本ペイント株式会社 Serum separation sealant
JP3358660B2 (en) * 1993-07-30 2002-12-24 ヘンケル コーポレーション Polyester for blood separation
TW404835B (en) 1994-10-05 2000-09-11 Becton Dickinson Co A viscoelastic dispersion composition
US5997811A (en) * 1997-07-02 1999-12-07 Cohesion Technologies, Inc. Method for sterile syringe packaging and handling
US5968018A (en) * 1996-10-30 1999-10-19 Cohesion Corporation Cell separation device and in-line orifice mixer system
US6166187A (en) * 1999-03-05 2000-12-26 The Regents Of The University Of California Method of concentrating prion proteins in blood samples
EP1230028B1 (en) * 1999-05-28 2008-07-16 Bio/Data Corporation Method and apparatus for directly sampling a fluid for microfiltration
US7288195B2 (en) * 1999-05-28 2007-10-30 Bio/Data Corporation Method and apparatus for directly sampling a fluid for microfiltration
US6376210B1 (en) 1999-07-06 2002-04-23 General Atomics Methods and compositions for assaying analytes
US7192729B2 (en) 1999-07-06 2007-03-20 General Atomics Methods for assaying homocysteine
US7947236B2 (en) 1999-12-03 2011-05-24 Becton, Dickinson And Company Device for separating components of a fluid sample
AU2001227679A1 (en) * 2000-02-25 2001-09-03 General Atomics Mutant nucleic binding enzymes and use thereof in diagnostic, detection and purification methods
US6610504B1 (en) 2000-04-10 2003-08-26 General Atomics Methods of determining SAM-dependent methyltransferase activity using a mutant SAH hydrolase
US6852874B2 (en) * 2000-10-02 2005-02-08 The Scripps Research Institute Second cycle asymmetric dihydroxylation reaction
US6878346B2 (en) * 2002-05-17 2005-04-12 Bayer Corporation Serum transfer cup
US7517694B2 (en) * 2002-07-26 2009-04-14 Ortho-Clinical Diagnostics, Inc. Metering tip with internal features to control fluid meniscus and oscillation
US7833545B2 (en) * 2003-04-29 2010-11-16 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
US7384760B2 (en) * 2004-04-30 2008-06-10 General Atomics Methods for assaying inhibitors of S-adenosylhomocysteine (SAH) hydrolase and S-adenosylmethionine (SAM)-dependent methyltransferase
US7766900B2 (en) 2005-02-21 2010-08-03 Biomet Manufacturing Corp. Method and apparatus for application of a fluid
US7674388B2 (en) * 2005-08-10 2010-03-09 The Regents Of The University Of California Photopolymer serum separator
US9248447B2 (en) * 2005-08-10 2016-02-02 The Regents Of The University Of California Polymers for use in centrifugal separation of liquids
US7673758B2 (en) 2005-08-10 2010-03-09 The Regents Of The University Of California Collection tubes apparatus, systems, and methods
US7971730B2 (en) 2005-08-10 2011-07-05 The Regents Of The University Of California Collection tubes apparatus, systems and methods
US20070190148A1 (en) * 2006-02-14 2007-08-16 Peter Cronin Gel compositions, apparatuses and fluid separation methods
US20080017577A1 (en) * 2006-07-21 2008-01-24 Becton, Dickinson And Company Membrane-based Double-layer Tube for Sample Collections
US8518272B2 (en) 2008-04-04 2013-08-27 Biomet Biologics, Llc Sterile blood separating system
US8182769B2 (en) 2008-04-04 2012-05-22 Biomet Biologics, Llc Clean transportation system
MX366109B (en) * 2008-07-21 2019-06-26 Becton Dickinson Co Density phase separation device.
CN104588140B (en) 2008-07-21 2016-06-29 贝克顿·迪金森公司 Density phase separation device
EP2517792B1 (en) 2008-07-21 2013-12-18 Becton, Dickinson and Company Density phase separation device
JP5516414B2 (en) * 2008-11-07 2014-06-11 日立化成株式会社 Serum or plasma separator and blood collection tube using the same
BR122021008555B1 (en) 2009-05-15 2022-03-03 Becton, Dickinson And Company SEPARATION SET FOR SEPARATING A FLUID SAMPLE IN FIRST PHASE AND SECOND PHASE
US8377395B2 (en) 2010-04-29 2013-02-19 Charles M. Coleman Integrated blood specimen processor
CN102872616B (en) * 2012-09-26 2014-10-01 成都众睿达科技有限公司 Blood separating gel and preparation method thereof
US9669405B2 (en) 2012-10-22 2017-06-06 The Regents Of The University Of California Sterilizable photopolymer serum separator
US10449117B2 (en) * 2014-09-24 2019-10-22 Q Holding Company Stopper for medicament containers
US9694359B2 (en) 2014-11-13 2017-07-04 Becton, Dickinson And Company Mechanical separator for a biological fluid
WO2017100798A1 (en) * 2015-12-11 2017-06-15 Siemens Healthcare Diagnostics Inc. Specimen container and method for separating serum or plasma from whole blood

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US3508653A (en) * 1967-11-17 1970-04-28 Charles M Coleman Method and apparatus for fluid handling and separation
US3647070A (en) * 1970-06-11 1972-03-07 Technicon Corp Method and apparatus for the provision of fluid interface barriers

Also Published As

Publication number Publication date
DE2340199A1 (en) 1975-02-27
CH611424A5 (en) 1979-05-31
DE2340199B2 (en) 1975-12-11
FR2240668A5 (en) 1975-03-07
US3780935A (en) 1973-12-25

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years

Effective date: 19930805