GB1440214A - Vaccines in solid particulate form - Google Patents

Vaccines in solid particulate form

Info

Publication number
GB1440214A
GB1440214A GB4181273A GB4181273A GB1440214A GB 1440214 A GB1440214 A GB 1440214A GB 4181273 A GB4181273 A GB 4181273A GB 4181273 A GB4181273 A GB 4181273A GB 1440214 A GB1440214 A GB 1440214A
Authority
GB
United Kingdom
Prior art keywords
animal
particles
particulate form
solid particulate
vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4181273A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Illinois
University of Illinois Foundation
Original Assignee
University of Illinois
University of Illinois Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00285036A external-priority patent/US3823228A/en
Application filed by University of Illinois, University of Illinois Foundation filed Critical University of Illinois
Publication of GB1440214A publication Critical patent/GB1440214A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A61K39/225—Porcine transmissible gastroenteritis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

1440214 Vaccines in solid particulate form UNIVERSITY OF ILLINOIS FOUNDATION 5 Sept 1973 41812/73 Heading A5B Pharmaceutical preparations for oral administration to animals comprise a villiarly effective attenuated virus vaccine e.g. transmissible gastroenteritis (TGE) vaccine in solid particulate form, the vaccine being subject to degradation by contact with the gastric secretions off the animal, and an enteric coating e.g. cellulose acetate phthalate, covering each particle, the particles having a maximum diameter of 2.0 mm such that they will pass from the stomach through the pyloric valve into the intestine of the animal before the enteric coating is destroyed by the gastric secretions. The particles are preferably spherical or approximately spherical and may additionally comprise a solid physiologically acceptable carrier e.g. an animal feedstuff. The particles may be encapsulated in a material which dissolves rapidly in the stomach of the animal e.g. gelatin.
GB4181273A 1972-08-30 1973-09-05 Vaccines in solid particulate form Expired GB1440214A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00285036A US3823228A (en) 1971-09-29 1972-08-30 Tge virus vaccine

Publications (1)

Publication Number Publication Date
GB1440214A true GB1440214A (en) 1976-06-23

Family

ID=23092469

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4181273A Expired GB1440214A (en) 1972-08-30 1973-09-05 Vaccines in solid particulate form

Country Status (9)

Country Link
JP (1) JPS535371B2 (en)
AR (1) AR197158A1 (en)
AU (1) AU5949773A (en)
CA (1) CA1023266A (en)
DE (1) DE2343570A1 (en)
FR (1) FR2197576B1 (en)
GB (1) GB1440214A (en)
NL (1) NL7312032A (en)
PH (1) PH10296A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009577A1 (en) * 1978-08-18 1980-04-16 Burns-Biotec Laboratories Inc. An oral vaccine preparation and a method for increasing the resistance of swine to swine-dysentery infection
WO1999013869A1 (en) * 1997-09-12 1999-03-25 Gerold Lukowski Humidity-proof and gastric juice-resistant medications for animals

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS584561Y2 (en) * 1980-11-26 1983-01-26 日本濾過器株式会社 bubble separator
DK150008C (en) * 1981-11-20 1987-05-25 Benzon As Alfred PROCEDURE FOR THE PREPARATION OF A PHARMACEUTICAL ORAL POLYDEPOT PREPARATION
US6024983A (en) * 1986-10-24 2000-02-15 Southern Research Institute Composition for delivering bioactive agents for immune response and its preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3458621A (en) * 1966-08-31 1969-07-29 American Home Prod Tablet dosage-form for the immunization of the intestinal tract with live virus preparations
US3519710A (en) * 1967-08-10 1970-07-07 Edmund P Bass Direct active modified live virus vaccine immunization against transmissible gastroenteritis in swine piglets at birth

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009577A1 (en) * 1978-08-18 1980-04-16 Burns-Biotec Laboratories Inc. An oral vaccine preparation and a method for increasing the resistance of swine to swine-dysentery infection
WO1999013869A1 (en) * 1997-09-12 1999-03-25 Gerold Lukowski Humidity-proof and gastric juice-resistant medications for animals

Also Published As

Publication number Publication date
FR2197576B1 (en) 1976-09-03
CA1023266A (en) 1977-12-27
FR2197576A1 (en) 1974-03-29
JPS535371B2 (en) 1978-02-27
JPS4962618A (en) 1974-06-18
AR197158A1 (en) 1974-03-15
DE2343570A1 (en) 1974-03-14
AU5949773A (en) 1975-02-27
PH10296A (en) 1976-11-10
NL7312032A (en) 1975-03-04

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees