GB1438800A - Cephalosporin derivatives and preparation thereof - Google Patents
Cephalosporin derivatives and preparation thereofInfo
- Publication number
- GB1438800A GB1438800A GB2990173A GB2990173A GB1438800A GB 1438800 A GB1438800 A GB 1438800A GB 2990173 A GB2990173 A GB 2990173A GB 2990173 A GB2990173 A GB 2990173A GB 1438800 A GB1438800 A GB 1438800A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- compound
- reacting
- give
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001780 cephalosporins Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 8
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 abstract 6
- 239000003795 chemical substances by application Substances 0.000 abstract 5
- -1 Cephem compounds Chemical class 0.000 abstract 3
- 230000000269 nucleophilic effect Effects 0.000 abstract 2
- 239000000376 reactant Substances 0.000 abstract 2
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 2
- IVRMZWNICZWHMI-UHFFFAOYSA-N Azide Chemical compound [N-]=[N+]=[N-] IVRMZWNICZWHMI-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000006266 etherification reaction Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- ODUCDPQEXGNKDN-UHFFFAOYSA-N nitroxyl Chemical compound O=N ODUCDPQEXGNKDN-UHFFFAOYSA-N 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6463072A JPS5521754B2 (enrdf_load_stackoverflow) | 1972-06-27 | 1972-06-27 | |
| JP6462972A JPS5525194B2 (enrdf_load_stackoverflow) | 1972-06-27 | 1972-06-27 | |
| JP6463172A JPS4924994A (enrdf_load_stackoverflow) | 1972-06-27 | 1972-06-27 | |
| JP6557472A JPS5429517B2 (enrdf_load_stackoverflow) | 1972-06-29 | 1972-06-29 | |
| JP6557572A JPS5525195B2 (enrdf_load_stackoverflow) | 1972-06-29 | 1972-06-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1438800A true GB1438800A (en) | 1976-06-09 |
Family
ID=27523854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2990173A Expired GB1438800A (en) | 1972-06-27 | 1973-06-22 | Cephalosporin derivatives and preparation thereof |
Country Status (6)
| Country | Link |
|---|---|
| CA (1) | CA1015745A (enrdf_load_stackoverflow) |
| CH (1) | CH601312A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2332045A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2208909B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1438800A (enrdf_load_stackoverflow) |
| SE (1) | SE420837B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6642020B2 (en) | 2001-04-19 | 2003-11-04 | Bioferma Murcia S.A. | Process for preparing cephalosporin derivatives |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1565941A (en) | 1977-02-08 | 1980-04-23 | Toyama Chemical Co Ltd | Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids |
| JPS6027677B2 (ja) | 1978-07-06 | 1985-06-29 | 富山化学工業株式会社 | ７−置換又は非置換アミノ−３−置換チオメチルセフエムカルボン酸類の新規製造法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH481142A (de) * | 1966-12-05 | 1969-11-15 | Ciba Geigy | Verfahren zur Isolierung von Cephalosporin C |
| BE759064A (fr) * | 1969-12-17 | 1971-05-17 | Lilly Co Eli | Une methode pour transformer la cephalosporine c. en un derive soluble dans un solvant organique, et le compose qui en |
| GB1311268A (en) * | 1971-01-26 | 1973-03-28 | Pfizer | Process for the isolation of n-benzoyl cephalosporin c |
-
1973
- 1973-06-20 CA CA174,531A patent/CA1015745A/en not_active Expired
- 1973-06-22 GB GB2990173A patent/GB1438800A/en not_active Expired
- 1973-06-23 DE DE19732332045 patent/DE2332045A1/de not_active Withdrawn
- 1973-06-26 FR FR7323340A patent/FR2208909B1/fr not_active Expired
- 1973-06-26 SE SE7309001A patent/SE420837B/xx unknown
- 1973-06-27 CH CH939373A patent/CH601312A5/xx not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6642020B2 (en) | 2001-04-19 | 2003-11-04 | Bioferma Murcia S.A. | Process for preparing cephalosporin derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| CH601312A5 (enrdf_load_stackoverflow) | 1978-07-14 |
| CA1015745A (en) | 1977-08-16 |
| FR2208909A1 (enrdf_load_stackoverflow) | 1974-06-28 |
| DE2332045A1 (de) | 1974-01-10 |
| SE420837B (sv) | 1981-11-02 |
| FR2208909B1 (enrdf_load_stackoverflow) | 1978-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |