GB1438180A - 1,2,4-benzotriazine derivatives their production and their pharmaceutical and veterinary use - Google Patents
1,2,4-benzotriazine derivatives their production and their pharmaceutical and veterinary useInfo
- Publication number
- GB1438180A GB1438180A GB5306973A GB5306973A GB1438180A GB 1438180 A GB1438180 A GB 1438180A GB 5306973 A GB5306973 A GB 5306973A GB 5306973 A GB5306973 A GB 5306973A GB 1438180 A GB1438180 A GB 1438180A
- Authority
- GB
- United Kingdom
- Prior art keywords
- optionally substituted
- benzotriazine
- dioxides
- formula
- substituted alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
- C07D253/10—Condensed 1,2,4-triazines; Hydrogenated condensed 1,2,4-triazines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Food Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
1438180 1,2,4 - Benzotriazine - 1,4 - dioxides BAYER AG 15 Nov 1973 [15 Nov 1972] 53069/73 Heading C2C 1,2,4 - Benzotriazine - 1,4 - dioxides of the Formula I wherein X<SP>1</SP> and X<SP>2</SP> are H, optionally substituted alkyl, optionally substituted alkoxy, optionally substituted alkenyl or halogen; R<SP>1</SP> and R<SP>2</SP> are H, optionally substituted alkyl, optionally substituted alkenyl or optionally substituted cycloalkyl, or R<SP>1</SP> and R<SP>2</SP> together with the nitrogen atom to which they are attached form a heterocyclic ring, the compound being novel, provided that neither R<SP>1</SP> nor R<SP>2</SP> is H when the other is optionally substituted alkyl or optionally substituted cycloalkyl, except when one or both of X<SP>1</SP> and X<SP>2</SP> is optionally substituted alkenyl, are prepared by reacting compound of the formula with 2 - oxo - [1,2,4]oxadiazolo[2,3 - c][1,2,4]- benzotriazine-5-oxides of the Formula II 2 - Oxo - [1,2,4]oxodiazolo[2,3-c][1,2,4]benzotriazine-5-oxide is prepared by reacting phosgene with 3-amino-1,2,4-benzotriazine-1,4-dioxide, obtained by treating benzofuroxan with disodium cyanamide. Pharmaceutical compositions, suitable for oral, parenteral, topical or rectal administration, contain the above 1,2,4-benzotriazine-1,4-dioxides in admixture with solid or liquid diluents or carriers.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2255946A DE2255946A1 (en) | 1972-11-15 | 1972-11-15 | PROCESS FOR THE MANUFACTURING OF NEW SQUARE CLIP ON 3-BENZO-1,2,4-TRIAZINYL DIOXIDE (1.4) SQUARE CLIP TO -URA, AND THEIR USE AS A MEDICINAL PRODUCT AND FEED ADDITIVE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1438180A true GB1438180A (en) | 1976-06-03 |
Family
ID=5861793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5306973A Expired GB1438180A (en) | 1972-11-15 | 1973-11-15 | 1,2,4-benzotriazine derivatives their production and their pharmaceutical and veterinary use |
Country Status (21)
| Country | Link |
|---|---|
| JP (2) | JPS4980084A (en) |
| AR (1) | AR199806A1 (en) |
| AT (1) | AT330793B (en) |
| AU (1) | AU6242973A (en) |
| BE (1) | BE807308A (en) |
| BR (1) | BR7308899D0 (en) |
| CH (1) | CH586213A5 (en) |
| CS (1) | CS177870B2 (en) |
| DE (1) | DE2255946A1 (en) |
| DK (1) | DK133985C (en) |
| ES (1) | ES420537A1 (en) |
| FR (1) | FR2206103B1 (en) |
| GB (1) | GB1438180A (en) |
| HU (1) | HU168894B (en) |
| IL (1) | IL43613A (en) |
| LU (1) | LU68791A1 (en) |
| NL (1) | NL7315455A (en) |
| PL (1) | PL87630B1 (en) |
| SE (1) | SE394815B (en) |
| SU (1) | SU479285A3 (en) |
| ZA (1) | ZA738730B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115894385A (en) * | 2023-01-09 | 2023-04-04 | 中国科学院长春应用化学研究所 | Tirapazamine derivative and preparation method and application thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5672702A (en) * | 1995-12-04 | 1997-09-30 | Sanofi | Process for preparing 3 amino 1, 2, 4-benzotriazine dioxide |
-
1972
- 1972-11-15 DE DE2255946A patent/DE2255946A1/en active Pending
-
1973
- 1973-11-12 NL NL7315455A patent/NL7315455A/xx not_active Application Discontinuation
- 1973-11-12 IL IL43613A patent/IL43613A/en unknown
- 1973-11-13 AU AU62429/73A patent/AU6242973A/en not_active Expired
- 1973-11-13 PL PL1973166511A patent/PL87630B1/zh unknown
- 1973-11-13 LU LU68791A patent/LU68791A1/xx unknown
- 1973-11-13 JP JP48126876A patent/JPS4980084A/ja active Pending
- 1973-11-13 BR BR8899/73A patent/BR7308899D0/en unknown
- 1973-11-13 CH CH1594173A patent/CH586213A5/xx not_active IP Right Cessation
- 1973-11-13 JP JP48126877A patent/JPS4980217A/ja active Pending
- 1973-11-13 SU SU1967997A patent/SU479285A3/en active
- 1973-11-14 HU HUBA2996A patent/HU168894B/hu unknown
- 1973-11-14 SE SE7315439A patent/SE394815B/en unknown
- 1973-11-14 BE BE137736A patent/BE807308A/en unknown
- 1973-11-14 CS CS7820A patent/CS177870B2/cs unknown
- 1973-11-14 ZA ZA738730A patent/ZA738730B/en unknown
- 1973-11-14 ES ES420537A patent/ES420537A1/en not_active Expired
- 1973-11-14 DK DK615773A patent/DK133985C/en active
- 1973-11-15 AR AR252018A patent/AR199806A1/en active
- 1973-11-15 AT AT961373A patent/AT330793B/en not_active IP Right Cessation
- 1973-11-15 GB GB5306973A patent/GB1438180A/en not_active Expired
- 1973-11-15 FR FR7340748A patent/FR2206103B1/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115894385A (en) * | 2023-01-09 | 2023-04-04 | 中国科学院长春应用化学研究所 | Tirapazamine derivative and preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| ATA961373A (en) | 1975-10-15 |
| IL43613A (en) | 1977-06-30 |
| AT330793B (en) | 1976-07-26 |
| HU168894B (en) | 1976-08-28 |
| DE2255946A1 (en) | 1974-05-22 |
| SU479285A3 (en) | 1975-07-30 |
| FR2206103B1 (en) | 1977-09-02 |
| DK133985B (en) | 1976-08-23 |
| CS177870B2 (en) | 1977-08-31 |
| FR2206103A1 (en) | 1974-06-07 |
| DK133985C (en) | 1977-01-31 |
| PL87630B1 (en) | 1976-07-31 |
| AU6242973A (en) | 1975-05-15 |
| LU68791A1 (en) | 1974-01-21 |
| JPS4980084A (en) | 1974-08-02 |
| ZA738730B (en) | 1974-09-25 |
| ES420537A1 (en) | 1976-04-01 |
| BE807308A (en) | 1974-05-14 |
| IL43613A0 (en) | 1974-03-14 |
| CH586213A5 (en) | 1977-03-31 |
| NL7315455A (en) | 1974-05-17 |
| SE394815B (en) | 1977-07-11 |
| AR199806A1 (en) | 1974-09-30 |
| BR7308899D0 (en) | 1974-09-24 |
| JPS4980217A (en) | 1974-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |