GB1437801A - Synthetic antigens - Google Patents
Synthetic antigensInfo
- Publication number
- GB1437801A GB1437801A GB2295973A GB2295973A GB1437801A GB 1437801 A GB1437801 A GB 1437801A GB 2295973 A GB2295973 A GB 2295973A GB 2295973 A GB2295973 A GB 2295973A GB 1437801 A GB1437801 A GB 1437801A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hemisuccinate
- compound
- carboxyphenylhydrazone
- reacting
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108010008038 Synthetic Vaccines Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- HLCRYAZDZCJZFG-BDXSIMOUSA-N (8s,9s,13s,14s)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene Chemical compound C1CC2=CC=CC=C2[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 HLCRYAZDZCJZFG-BDXSIMOUSA-N 0.000 abstract 3
- 150000003431 steroids Chemical class 0.000 abstract 3
- GOUHYARYYWKXHS-UHFFFAOYSA-N 4-formylbenzoic acid Chemical compound OC(=O)C1=CC=C(C=O)C=C1 GOUHYARYYWKXHS-UHFFFAOYSA-N 0.000 abstract 2
- ICDVPZJTOWXNSP-UHFFFAOYSA-M 4-hydroxy-4-oxobutanoate;tetramethylazanium Chemical compound C[N+](C)(C)C.OC(=O)CCC([O-])=O ICDVPZJTOWXNSP-UHFFFAOYSA-M 0.000 abstract 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- 108091003079 Bovine Serum Albumin Proteins 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 229940098773 bovine serum albumin Drugs 0.000 abstract 2
- DTGDZMYNKLTSKC-HKQCOZBKSA-N cholest-5-ene Chemical compound C1C=C2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 DTGDZMYNKLTSKC-HKQCOZBKSA-N 0.000 abstract 2
- DTGDZMYNKLTSKC-UHFFFAOYSA-N cholest-5-ene Natural products C1C=C2CCCCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 DTGDZMYNKLTSKC-UHFFFAOYSA-N 0.000 abstract 2
- ALQLPWJFHRMHIU-UHFFFAOYSA-N 1,4-diisocyanatobenzene Chemical compound O=C=NC1=CC=C(N=C=O)C=C1 ALQLPWJFHRMHIU-UHFFFAOYSA-N 0.000 abstract 1
- NVKAWKQGWWIWPM-ABEVXSGRSA-N 17-β-hydroxy-5-α-Androstan-3-one Chemical compound C1C(=O)CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CC[C@H]21 NVKAWKQGWWIWPM-ABEVXSGRSA-N 0.000 abstract 1
- FALRKNHUBBKYCC-UHFFFAOYSA-N 2-(chloromethyl)pyridine-3-carbonitrile Chemical compound ClCC1=NC=CC=C1C#N FALRKNHUBBKYCC-UHFFFAOYSA-N 0.000 abstract 1
- YOETUEMZNOLGDB-UHFFFAOYSA-N 2-methylpropyl carbonochloridate Chemical compound CC(C)COC(Cl)=O YOETUEMZNOLGDB-UHFFFAOYSA-N 0.000 abstract 1
- PCNFLKVWBDNNOW-UHFFFAOYSA-N 4-hydrazinylbenzoic acid Chemical compound NNC1=CC=C(C(O)=O)C=C1 PCNFLKVWBDNNOW-UHFFFAOYSA-N 0.000 abstract 1
- XNPOFXIBHOVFFH-UHFFFAOYSA-N N-cyclohexyl-N'-(2-(4-morpholinyl)ethyl)carbodiimide Chemical compound C1CCCCC1N=C=NCCN1CCOCC1 XNPOFXIBHOVFFH-UHFFFAOYSA-N 0.000 abstract 1
- 241000237988 Patellidae Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229960003473 androstanolone Drugs 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- OMWQUXGVXQELIX-UHFFFAOYSA-N bitoscanate Chemical compound S=C=NC1=CC=C(N=C=S)C=C1 OMWQUXGVXQELIX-UHFFFAOYSA-N 0.000 abstract 1
- 239000003118 drug derivative Substances 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 108010074605 gamma-Globulins Proteins 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- -1 p-phenylenediamino Chemical group 0.000 abstract 1
- 229960002695 phenobarbital Drugs 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 229940014800 succinic anhydride Drugs 0.000 abstract 1
- LXEJRKJRKIFVNY-UHFFFAOYSA-N terephthaloyl chloride Chemical compound ClC(=O)C1=CC=C(C(Cl)=O)C=C1 LXEJRKJRKIFVNY-UHFFFAOYSA-N 0.000 abstract 1
- IMFACGCPASFAPR-UHFFFAOYSA-N tributylamine Chemical compound CCCCN(CCCC)CCCC IMFACGCPASFAPR-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9406—Neurotransmitters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25363272A | 1972-05-15 | 1972-05-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1437801A true GB1437801A (en) | 1976-06-03 |
Family
ID=22961066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2295973A Expired GB1437801A (en) | 1972-05-15 | 1973-05-15 | Synthetic antigens |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS4941526A (enrdf_load_stackoverflow) |
AT (1) | AT340065B (enrdf_load_stackoverflow) |
DE (1) | DE2324544A1 (enrdf_load_stackoverflow) |
FR (1) | FR2184847B1 (enrdf_load_stackoverflow) |
GB (1) | GB1437801A (enrdf_load_stackoverflow) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0028795A3 (en) * | 1979-11-13 | 1982-03-31 | Miles Laboratories Inc. | Valproic acid konjugates, antibodies thereto and intermediates for their preparation |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1446536A (en) * | 1975-02-21 | 1976-08-18 | Yeda Res & Dev | Pharmaceutically active compositions |
JPS51101120A (en) * | 1975-02-28 | 1976-09-07 | Dai Ichi Kogyo Seiyaku Co Ltd | Kogen oyobi kotainoseiho |
IL47372A (en) * | 1975-05-27 | 1979-10-31 | Yeda Res & Dev | Fab'dimers bound to daunomycin or adriamycin,their preparation and pharmaceutical compositions containing same |
JPS5366417A (en) * | 1976-11-25 | 1978-06-13 | Dainippon Pharmaceut Co Ltd | Haptene antigens |
US4069105A (en) * | 1977-03-03 | 1978-01-17 | Syva Company | Lidocaine antigens and antibodies |
GB2013688B (en) * | 1978-01-26 | 1982-06-30 | Technicon Instr | Insolubilised proteins and immunoassays utilising them |
US4264571A (en) * | 1979-01-22 | 1981-04-28 | George Washington University | Radioimmunoassay of thymosin α1 |
US4243608A (en) * | 1979-05-14 | 1981-01-06 | E. R. Squibb & Sons, Inc. | 3-(4-Hydroxyphenyl)pentanedioic acid, monohydrazide, derivatives and analogs |
US4587046A (en) * | 1982-05-18 | 1986-05-06 | The Regents Of The University Of California | Drug-carrier conjugates |
US4486344A (en) * | 1983-03-28 | 1984-12-04 | Miles Laboratories, Inc. | Urea-linked immunogens, antibodies, and preparative method |
-
1973
- 1973-05-15 DE DE19732324544 patent/DE2324544A1/de active Pending
- 1973-05-15 AT AT426073A patent/AT340065B/de not_active IP Right Cessation
- 1973-05-15 FR FR7317496A patent/FR2184847B1/fr not_active Expired
- 1973-05-15 JP JP5327273A patent/JPS4941526A/ja active Pending
- 1973-05-15 GB GB2295973A patent/GB1437801A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0028795A3 (en) * | 1979-11-13 | 1982-03-31 | Miles Laboratories Inc. | Valproic acid konjugates, antibodies thereto and intermediates for their preparation |
Also Published As
Publication number | Publication date |
---|---|
FR2184847B1 (enrdf_load_stackoverflow) | 1978-05-26 |
AU5570273A (en) | 1974-11-21 |
AT340065B (de) | 1977-11-25 |
ATA426073A (de) | 1977-03-15 |
FR2184847A1 (enrdf_load_stackoverflow) | 1973-12-28 |
DE2324544A1 (de) | 1973-11-29 |
JPS4941526A (enrdf_load_stackoverflow) | 1974-04-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |