GB1429325A - Apparatus for precision metering of fluids - Google Patents

Apparatus for precision metering of fluids

Info

Publication number
GB1429325A
GB1429325A GB5412973A GB5412973A GB1429325A GB 1429325 A GB1429325 A GB 1429325A GB 5412973 A GB5412973 A GB 5412973A GB 5412973 A GB5412973 A GB 5412973A GB 1429325 A GB1429325 A GB 1429325A
Authority
GB
United Kingdom
Prior art keywords
section
conduit
fluid
syringe
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5412973A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of GB1429325A publication Critical patent/GB1429325A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0227—Details of motor drive means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
    • G01F11/021—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type
    • G01F11/029—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type provided with electric controlling means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/2931—Diverse fluid containing pressure systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Fluid Mechanics (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

1429325 Sampling liquids ABBOTT LABORATORIES 21 Nov 1973 [22 Dec 1972] 54129/73 Heading B8N [Also in Divisions G1 and F1] Apparatus for the precision metering of fluids comprises a first capillary conduit 7, 9 having in it a minute aperture 8, a second capillary conduit 11 having one end intersecting the first conduit at the aperture, the aperture then dividing the first conduit into a section 9 and a section 7 which is common to both conduits and providing first and second fluid paths 9, 7 and 11, 7, the aperture 8 allowing formation of a first interface between the first fluid path and conduit 11 (Fig. 3c, not shown) and a second interface between the second path and section 9 of the first conduit (Fig. 3a, not shown), liquid then traversing each of the fluid paths substantially free from contamination from the other fluid path, the apparatus also including a first syringe 15 connected to the end of the conduit section 9 and a second syringe connected to the end of the second conduit 11, each syringe having a movable piston. In the apparatus shown, the first fluid (A), which may be saline, is stored in syringes 15, 23 and the second fluid (B), which may be a silicone oil, is stored in syringes 19, 47. Initially the section 9 is filled with A and section 7, 11 with B. Sample is aspirated into sections 7, 11 by a retraction of piston 49 of syringe 19. Sample is flushed out of section 7 by forcing fluid A from syringe 15 by means of piston 25 through line 13 and sections 9, 7. Sample is dispensed together with some fluid A by operation of piston 49 by a precise amount corresponding to the amount of sample to be dispensed. The remainder of the sample in section 7 is rinsed away by operation of piston 25 to force fluid A into sections 9, 7.
GB5412973A 1972-12-22 1973-11-21 Apparatus for precision metering of fluids Expired GB1429325A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31775372 US3831618A (en) 1972-12-22 1972-12-22 Apparatus for the precision metering of fluids

Publications (1)

Publication Number Publication Date
GB1429325A true GB1429325A (en) 1976-03-24

Family

ID=23235124

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5412973A Expired GB1429325A (en) 1972-12-22 1973-11-21 Apparatus for precision metering of fluids

Country Status (7)

Country Link
US (1) US3831618A (en)
JP (1) JPS5326974B2 (en)
CA (1) CA1006475A (en)
DE (1) DE2364099A1 (en)
FR (1) FR2211645B1 (en)
GB (1) GB1429325A (en)
IT (1) IT1001417B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125487A (en) * 1982-08-18 1984-03-07 Hpw Ltd Infusion-aspiration apparatus

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002269A (en) * 1974-08-16 1977-01-11 Technicon Instruments Corporation Liquid proportioning system in a liquid sample analyzer
US4189943A (en) * 1975-03-25 1980-02-26 Faure Jean M Apparatus for volume measurement of liquids
CA1043128A (en) * 1975-04-02 1978-11-28 Technicon Instruments Corporation Liquid proportioning system in a liquid sample analyzer
US3991616A (en) * 1975-09-08 1976-11-16 Hans Noll Automatic pipetter
HU171920B (en) * 1975-12-30 1978-04-28 Mueszeripari Muevek Lab Device for blood-typing
US4101283A (en) * 1976-07-13 1978-07-18 Karl Erik Sundstrom Disposable reagent container and actuation mechanism
ZA784744B (en) * 1977-08-31 1979-08-29 C Jottier Apparatus for the treatment of fluids
US4203817A (en) * 1979-03-06 1980-05-20 Jenoptik Jena G.M.B.H. Method of and device for moving liquid samples
US4333356A (en) * 1979-04-27 1982-06-08 Ciba-Geigy Corporation Mixing apparatus
US4399711A (en) * 1980-04-18 1983-08-23 Beckman Instruments, Inc. Method and apparatus ensuring full volume pickup in an automated pipette
DE3136057A1 (en) * 1980-06-06 1982-07-15 Varian Techtron Pty Ltd SYRINGE DRIVE SYSTEM
US4407659A (en) * 1980-06-06 1983-10-04 Varian Associates, Inc. Drive system
EP0046345A3 (en) * 1980-08-15 1982-03-03 Ortho Diagnostic Systems Inc. Controlled hydrodynamic flow in flow cytometry systems
EP0082263A1 (en) * 1981-12-10 1983-06-29 The Perkin-Elmer Corporation Sample introduction for chemical analysis by spectrometry/liquid chromatography
DE3228935C2 (en) * 1982-08-03 1984-10-31 Rationator-Maschinenbau Gmbh, 6521 Hillesheim Device for moving metering pistons and filling tubes
EP0105834A3 (en) * 1982-09-07 1984-10-10 Greiner Instruments AG Method and apparatus for transferring a fluid sample to microlitre and millilitre aggregates
US4555957A (en) * 1983-10-14 1985-12-03 Cetus Corporation Bi-directional liquid sample handling system
FI834387A0 (en) * 1983-11-30 1983-11-30 Labsystems Oy FOERFARANDE FOER UTSPAEDNING AV VAETSKEPROV
EP0188453B1 (en) * 1984-07-06 1989-01-18 Metrohm Ag Device and method for quantitative and/or qualitative determination of liquids
US4593837A (en) * 1985-03-15 1986-06-10 Eastman Kodak Company Variable volume pipette
US4665760A (en) * 1986-02-12 1987-05-19 Combustion Engineering, Inc. Mounting and traversing assembly for in situ particle size measuring device
EP0327658B1 (en) * 1988-02-11 1991-10-23 Hewlett-Packard GmbH Sample injector for a liquid chromatograph
US5232664A (en) * 1991-09-18 1993-08-03 Ventana Medical Systems, Inc. Liquid dispenser
US5268147A (en) * 1992-02-26 1993-12-07 Miles, Inc. Reversible direction capsule chemistry sample liquid analysis system and method
US5507323A (en) * 1993-10-12 1996-04-16 Fujitsu Limited Method and dispenser for filling liquid crystal into LCD cell
GB9405028D0 (en) * 1994-03-15 1994-04-27 Counting Tech Ltd Fluid diluter
SE515423C2 (en) * 1998-02-06 2001-07-30 Boule Medical Ab Method and apparatus for diluting a blood sample
US6605472B1 (en) * 1998-10-09 2003-08-12 The Governors Of The University Of Alberta Microfluidic devices connected to glass capillaries with minimal dead volume
JP4194233B2 (en) * 2000-08-18 2008-12-10 シスメックス株式会社 Sheath liquid supply device, supply method, and sample analyzer
US7111757B1 (en) 2003-09-12 2006-09-26 O'brien Thomas Matthew Device and method for the volumetric measurement and dispensing of liquids
US20080080302A1 (en) * 2006-09-29 2008-04-03 Fujifilm Corporation Droplet mixing method and apparatus
DE102007004036B4 (en) * 2007-01-22 2017-08-03 Martin Schmäh Dosing device and method for producing a reagent mixture

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2797150A (en) * 1956-01-24 1957-06-25 Rigby Edward Apparatus for collecting a liquid sample
NL257371A (en) * 1959-10-30
US3431078A (en) * 1966-10-27 1969-03-04 Yasutsugu Yokohama Respiration measuring apparatus
FR1585020A (en) * 1968-05-08 1970-01-09
US3572130A (en) * 1969-08-27 1971-03-23 Nat Instr Lab Inc Liquid sample pick-up and dispensing apparatus

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125487A (en) * 1982-08-18 1984-03-07 Hpw Ltd Infusion-aspiration apparatus

Also Published As

Publication number Publication date
CA1006475A (en) 1977-03-08
US3831618A (en) 1974-08-27
FR2211645B1 (en) 1978-03-10
FR2211645A1 (en) 1974-07-19
DE2364099A1 (en) 1974-07-04
JPS5326974B2 (en) 1978-08-05
IT1001417B (en) 1976-04-20
JPS4991667A (en) 1974-09-02

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee