GB1428436A - Method for producing biologically tolerated polymers - Google Patents

Abstract

1428436 Polymers of conjugated dienols CESKOSLOVENSKA AKADEMIE VED 18 May 1973 [16 June 1972] 23938/73 Heading C3P Biologically tolerated polymers are prepared by the catalytic polymerization of a monomer system containing at least 60 mol. per cent of a conjugated diene having a linear chain, and containing 5-10 carbon atoms and at least one free -OH group or -OH group blocked by reaction with ClSi(CH 3 ) 3 . Hydroxy compounds may be polymerized by free radical mechanisms and blocked hydroxy compounds by ionic coordination mechanisms. Examples are given as follows: conjugated diene monomers: 2,4-pentadiene - 1 - ol, 2,4 - hexadiene - 1 - ol, 1,3- heptadiene - 5 - ol, 2,4 - octadiene - 6 - ol, 1,3- decadiene - 8,9 - diol and 2,4 - pentadiene - 1- oxytrimethylsilane; co-monomers: ethylene glycol dimethacrylate, 2-hydroxyethyl methacrylate, methylene-bis-acrylamide, methacrylic acid, dimethylaminoethyl methacrylate, propylene glycol monomethacrylate, diethylene glycol monomethacrylate, divinyl carbinol, triethylene glycol dimethacrylate, #-vinylacrylic acid, diethylaminoethyl methacrylate, 1,5- hexadiene-4-ol, divinyl methoxy silane, glycerol methacrylate and catalysts: benzoyl peroxide, cumene hydroperoxide, cyclohexanone peroxide, diisopropyl peroxycarbonate, tertbutyl peroxyacetate, azobisisobutyronitrile, 2,2<SP>1</SP>-azobis-2,4-dimethyl-4- methoxyvaleronitrile, methyl azobisisobutyrate, diethyl aluminium chloride/rhodium acetylacetonate and diethyl aluminium chloride/cobalt acetylacetonate/water; modifier: CBr 4 (Example 13); and solvents (when used): benzene, DMF, acetone, ethanol and pyridine. When solvent is absent polymerization is effected in a mould or between two glass plates. After-treatments.-Polymers of the blocked hydroxy compounds may be hydrolysed to produce free hydroxy groups (Examples 9 and 10), and examples are also given of cross-linking the hydroxy polymers with ammonium bichromate (Example 13) or by reaction with toluene di-isocyanate (Example 12). Uses.-Manufacture of biomedical materials, e.g. heart valves, tubular implants, contact lenses, and haemodialysis or reverse osmosis membranes; coatings for catheters and foods; protection of roads and building materials; and binders of biologically active compounds.