GB1427508A - Pyrido pyrimidine compounds - Google Patents
Pyrido pyrimidine compoundsInfo
- Publication number
- GB1427508A GB1427508A GB4749071A GB4749071A GB1427508A GB 1427508 A GB1427508 A GB 1427508A GB 4749071 A GB4749071 A GB 4749071A GB 4749071 A GB4749071 A GB 4749071A GB 1427508 A GB1427508 A GB 1427508A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- hydrogen
- atom
- thiol
- defined above
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000008518 pyridopyrimidines Chemical class 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000004414 alkyl thio group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 2
- 239000000047 product Substances 0.000 abstract 2
- 150000003573 thiols Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 abstract 1
- -1 acetyloxy, hydroxyl Chemical group 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- UDJFFSGCRRMVFH-UHFFFAOYSA-N pyrido[2,3-d]pyrimidine Chemical compound N1=CN=CC2=CC=CN=C21 UDJFFSGCRRMVFH-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
- 239000002023 wood Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (18)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE790014D BE790014A (fr) | 1971-10-12 | Pyrido (2,3-d) pyrimidines a usage therapeutique | |
| GB4749071A GB1427508A (en) | 1971-10-12 | 1971-10-12 | Pyrido pyrimidine compounds |
| AU47670/72A AU477075B2 (en) | 1971-10-12 | 1972-10-11 | PYRIDO [2,3-d] PYRIMIDINES |
| DK501672AA DK138045B (da) | 1971-10-12 | 1972-10-11 | Analogifremgangsmåde til fremstilling af pyrido (2,3-d) pyrimidiner. |
| ES407527A ES407527A1 (es) | 1971-10-12 | 1972-10-11 | Un metodo de preparar una pirido (2,3-d) pirimidina. |
| CH1493272A CH593279A5 (enExample) | 1971-10-12 | 1972-10-12 | |
| DE2250103A DE2250103A1 (de) | 1971-10-12 | 1972-10-12 | Pyrido-pyrimidine, verfahren zu ihrer herstellung und verfahrenszwischenprodukte |
| IL40559A IL40559A (en) | 1971-10-12 | 1972-10-12 | 2,3,4,8-tetrahydro-2,4-dioxo-8-d-ribitylpyrido(2,3-d)pyrimidine derivatives their preparation and pharmaceutical compositions containing them |
| NL7213799A NL7213799A (enExample) | 1971-10-12 | 1972-10-12 | |
| FI2830/72A FI55845C (fi) | 1971-10-12 | 1972-10-12 | Foerfarande foer framstaellning av en 8-d-ribityl-pyrido(2,3-d)pyrimidin |
| SE7213147A SE396754B (sv) | 1971-10-12 | 1972-10-12 | Forfarande for framstellning av 8-d-ribityl-pyrido(2,3-d)pyrimider |
| JP47102324A JPS4848498A (enExample) | 1971-10-12 | 1972-10-12 | |
| HUPA1146A HU166757B (enExample) | 1971-10-12 | 1972-10-12 | |
| CA154,153A CA989833A (en) | 1971-10-12 | 1972-10-12 | 8-d-ribitylpyrido (2,3-d)pyrimidines |
| ZA727274A ZA727274B (en) | 1971-10-12 | 1972-10-12 | Pyride(2,3-d)pyrimidines |
| FR7236196A FR2157854B1 (enExample) | 1971-10-12 | 1972-10-12 | |
| ES419362A ES419362A1 (es) | 1971-10-12 | 1973-10-05 | Un metodo para preparar una formulacion farmaceutica en ta- bletas que comprende un piridi(2,3-d)pirimidina. |
| US05/891,831 US4252946A (en) | 1971-10-12 | 1978-03-30 | Pyrido-[2,3-d]pyrimidine compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4749071A GB1427508A (en) | 1971-10-12 | 1971-10-12 | Pyrido pyrimidine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1427508A true GB1427508A (en) | 1976-03-10 |
Family
ID=10445172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4749071A Expired GB1427508A (en) | 1971-10-12 | 1971-10-12 | Pyrido pyrimidine compounds |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4252946A (enExample) |
| JP (1) | JPS4848498A (enExample) |
| AU (1) | AU477075B2 (enExample) |
| BE (1) | BE790014A (enExample) |
| CH (1) | CH593279A5 (enExample) |
| DE (1) | DE2250103A1 (enExample) |
| DK (1) | DK138045B (enExample) |
| ES (2) | ES407527A1 (enExample) |
| FI (1) | FI55845C (enExample) |
| FR (1) | FR2157854B1 (enExample) |
| GB (1) | GB1427508A (enExample) |
| HU (1) | HU166757B (enExample) |
| IL (1) | IL40559A (enExample) |
| NL (1) | NL7213799A (enExample) |
| SE (1) | SE396754B (enExample) |
| ZA (1) | ZA727274B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4288365A (en) | 1977-07-20 | 1981-09-08 | Burroughs Wellcome Co. | Pyrido derivatives |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE790014A (fr) * | 1971-10-12 | 1973-04-12 | Woods Hamish C S | Pyrido (2,3-d) pyrimidines a usage therapeutique |
| JPS5227797A (en) * | 1975-07-23 | 1977-03-02 | Hisamitsu Pharmaceut Co Inc | Process for preparing pyrido (2,3-d) pyrimidinedione derivatives |
| WO2004063195A1 (en) * | 2003-01-03 | 2004-07-29 | Sloan-Kettering Institute For Cancer Research | Pyridopyrimidine kinase inhibitors |
| EP3399026B1 (en) | 2010-06-14 | 2024-06-26 | The Scripps Research Institute | Reprogramming of cells to a new fate |
| WO2013113762A1 (en) | 2012-01-31 | 2013-08-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and kits for predicting the risk of having a cutaneous melanoma in a subject |
| US10457682B2 (en) * | 2016-10-21 | 2019-10-29 | Oregon Health & Science University | Small molecules that bind MR1 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3752816A (en) * | 1969-06-10 | 1973-08-14 | Sherwin Williams Co | Certain 3-substituted-pyrido(3,2-d)pyrimidine 2,4-(1h,3h)-diones |
| BE790014A (fr) * | 1971-10-12 | 1973-04-12 | Woods Hamish C S | Pyrido (2,3-d) pyrimidines a usage therapeutique |
| US3862191A (en) * | 1972-09-27 | 1975-01-21 | Pfizer | Pyrido{8 2,3-d{9 pyrimidin-4(3H)-one |
| US4113859A (en) * | 1972-10-12 | 1978-09-12 | Burroughs Wellcome Co. | Certain pyrido-pyrimidines for treating mammalian and avian infections |
| US3922275A (en) * | 1972-11-09 | 1975-11-25 | Hisamitsu Pharmaceutical Co | Pyrido{8 2,3-D{9 {0 pyrimidine-2,4(1H,3H)-diones |
| JPS5069096A (enExample) * | 1973-10-25 | 1975-06-09 |
-
0
- BE BE790014D patent/BE790014A/xx unknown
-
1971
- 1971-10-12 GB GB4749071A patent/GB1427508A/en not_active Expired
-
1972
- 1972-10-11 AU AU47670/72A patent/AU477075B2/en not_active Expired
- 1972-10-11 DK DK501672AA patent/DK138045B/da unknown
- 1972-10-11 ES ES407527A patent/ES407527A1/es not_active Expired
- 1972-10-12 JP JP47102324A patent/JPS4848498A/ja active Pending
- 1972-10-12 HU HUPA1146A patent/HU166757B/hu unknown
- 1972-10-12 FR FR7236196A patent/FR2157854B1/fr not_active Expired
- 1972-10-12 DE DE2250103A patent/DE2250103A1/de not_active Ceased
- 1972-10-12 SE SE7213147A patent/SE396754B/xx unknown
- 1972-10-12 FI FI2830/72A patent/FI55845C/fi active
- 1972-10-12 ZA ZA727274A patent/ZA727274B/xx unknown
- 1972-10-12 NL NL7213799A patent/NL7213799A/xx not_active Application Discontinuation
- 1972-10-12 IL IL40559A patent/IL40559A/en unknown
- 1972-10-12 CH CH1493272A patent/CH593279A5/xx not_active IP Right Cessation
-
1973
- 1973-10-05 ES ES419362A patent/ES419362A1/es not_active Expired
-
1978
- 1978-03-30 US US05/891,831 patent/US4252946A/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4288365A (en) | 1977-07-20 | 1981-09-08 | Burroughs Wellcome Co. | Pyrido derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| CH593279A5 (enExample) | 1977-11-30 |
| SE396754B (sv) | 1977-10-03 |
| ZA727274B (en) | 1974-05-29 |
| ES419362A1 (es) | 1977-05-16 |
| AU477075B2 (en) | 1976-10-14 |
| FR2157854A1 (enExample) | 1973-06-08 |
| AU4767072A (en) | 1974-04-26 |
| FI55845C (fi) | 1979-10-10 |
| DK138045C (enExample) | 1978-11-20 |
| BE790014A (fr) | 1973-04-12 |
| FR2157854B1 (enExample) | 1975-10-31 |
| IL40559A0 (en) | 1972-12-29 |
| FI55845B (fi) | 1979-06-29 |
| JPS4848498A (enExample) | 1973-07-09 |
| IL40559A (en) | 1976-11-30 |
| HU166757B (enExample) | 1975-05-28 |
| DE2250103A1 (de) | 1973-04-19 |
| DK138045B (da) | 1978-07-03 |
| US4252946A (en) | 1981-02-24 |
| NL7213799A (enExample) | 1973-04-16 |
| ES407527A1 (es) | 1975-11-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |