GB1426072A - Cephalosporins - Google Patents
CephalosporinsInfo
- Publication number
- GB1426072A GB1426072A GB257173A GB257173A GB1426072A GB 1426072 A GB1426072 A GB 1426072A GB 257173 A GB257173 A GB 257173A GB 257173 A GB257173 A GB 257173A GB 1426072 A GB1426072 A GB 1426072A
- Authority
- GB
- United Kingdom
- Prior art keywords
- resulting
- pyridyl
- triphenylmethylamino
- prop
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001780 cephalosporins Chemical class 0.000 title 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 4
- -1 1 - t - butoxycarbonyl - 1 - triphenylphosphoranylidenemethyl Chemical group 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 125000002843 carboxylic acid group Chemical group 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 238000010992 reflux Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- RIOQSEWOXXDEQQ-UHFFFAOYSA-N triphenylphosphine Chemical compound C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 RIOQSEWOXXDEQQ-UHFFFAOYSA-N 0.000 abstract 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- MNFORVFSTILPAW-UHFFFAOYSA-N azetidin-2-one Chemical compound O=C1CCN1 MNFORVFSTILPAW-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- KJIFKLIQANRMOU-UHFFFAOYSA-N oxidanium;4-methylbenzenesulfonate Chemical compound O.CC1=CC=C(S(O)(=O)=O)C=C1 KJIFKLIQANRMOU-UHFFFAOYSA-N 0.000 abstract 1
- 239000012286 potassium permanganate Substances 0.000 abstract 1
- PYKYQLRSHLIABH-UHFFFAOYSA-N tert-butyl 2-oxoacetate;hydrate Chemical compound O.CC(C)(C)OC(=O)C=O PYKYQLRSHLIABH-UHFFFAOYSA-N 0.000 abstract 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB257173A GB1426072A (en) | 1973-01-18 | 1973-01-18 | Cephalosporins |
| ZA740379A ZA74379B (en) | 1973-01-18 | 1973-01-18 | Cephalosporins |
| IL44035A IL44035A0 (en) | 1973-01-18 | 1974-01-17 | Novel cephalosporins and their preparation |
| AU64610/74A AU6461074A (en) | 1973-01-18 | 1974-01-17 | Cephalosporins |
| FR7401715A FR2214468B1 (enExample) | 1973-01-18 | 1974-01-18 | |
| JP49008453A JPS505393A (enExample) | 1973-01-18 | 1974-01-18 | |
| CH73174A CH592679A5 (enExample) | 1973-01-18 | 1974-01-18 | |
| DE2402465A DE2402465A1 (de) | 1973-01-18 | 1974-01-18 | Neue 7 beta-acylaminoceph-3-em-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen als wirkstoffe enthaltende arzneipraeparate |
| BE140006A BE809961A (fr) | 1973-01-18 | 1974-01-18 | Cephalosporines |
| ES422430A ES422430A1 (es) | 1973-01-18 | 1974-01-18 | Un procedimiento para la preparacion de nuevas cef-3-emas sustituidas. |
| AT43774A AT328615B (de) | 1973-01-18 | 1974-01-18 | Verfahren zur herstellung von neuen cephalosporinen |
| NL7400916A NL7400916A (enExample) | 1973-01-18 | 1974-01-23 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB257173A GB1426072A (en) | 1973-01-18 | 1973-01-18 | Cephalosporins |
| GB4900073 | 1973-10-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1426072A true GB1426072A (en) | 1976-02-25 |
Family
ID=26237598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB257173A Expired GB1426072A (en) | 1973-01-18 | 1973-01-18 | Cephalosporins |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS505393A (enExample) |
| AU (1) | AU6461074A (enExample) |
| CH (1) | CH592679A5 (enExample) |
| DE (1) | DE2402465A1 (enExample) |
| ES (1) | ES422430A1 (enExample) |
| FR (1) | FR2214468B1 (enExample) |
| GB (1) | GB1426072A (enExample) |
| IL (1) | IL44035A0 (enExample) |
| NL (1) | NL7400916A (enExample) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1241657A (en) * | 1967-08-21 | 1971-08-04 | Glaxo Lab Ltd | Improvements in or relating to cephalosporin compounds |
| BE791159A (fr) * | 1972-01-03 | 1973-05-09 | Beecham Group Ltd | Procede pour la preparation de cephemes |
| BE791161A (fr) * | 1972-01-03 | 1973-05-09 | Beecham Group Ltd | Procede pour la preparation d'analogues des cephalosporines |
| BE791160A (fr) * | 1972-01-03 | 1973-05-09 | Beecham Group Ltd | Nouveaux cephemes substitues |
-
1973
- 1973-01-18 GB GB257173A patent/GB1426072A/en not_active Expired
-
1974
- 1974-01-17 AU AU64610/74A patent/AU6461074A/en not_active Expired
- 1974-01-17 IL IL44035A patent/IL44035A0/xx unknown
- 1974-01-18 JP JP49008453A patent/JPS505393A/ja active Pending
- 1974-01-18 ES ES422430A patent/ES422430A1/es not_active Expired
- 1974-01-18 FR FR7401715A patent/FR2214468B1/fr not_active Expired
- 1974-01-18 DE DE2402465A patent/DE2402465A1/de active Pending
- 1974-01-18 CH CH73174A patent/CH592679A5/xx not_active IP Right Cessation
- 1974-01-23 NL NL7400916A patent/NL7400916A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2402465A1 (de) | 1974-08-01 |
| NL7400916A (enExample) | 1974-07-22 |
| FR2214468A1 (enExample) | 1974-08-19 |
| IL44035A0 (en) | 1974-05-16 |
| CH592679A5 (enExample) | 1977-10-31 |
| FR2214468B1 (enExample) | 1978-01-13 |
| ES422430A1 (es) | 1977-02-01 |
| AU6461074A (en) | 1975-07-17 |
| JPS505393A (enExample) | 1975-01-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |