GB1423932A - 4-amino-quinolines - Google Patents
4-amino-quinolinesInfo
- Publication number
- GB1423932A GB1423932A GB1101074A GB1101074A GB1423932A GB 1423932 A GB1423932 A GB 1423932A GB 1101074 A GB1101074 A GB 1101074A GB 1101074 A GB1101074 A GB 1101074A GB 1423932 A GB1423932 A GB 1423932A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- trifluoromethylthio
- march
- dihydroxypropyl
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000005011 4-aminoquinolines Chemical class 0.000 title 1
- -1 2,3-dihydroxypropyl Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 3
- VAMXMNNIEUEQDV-UHFFFAOYSA-N methyl anthranilate Chemical compound COC(=O)C1=CC=CC=C1N VAMXMNNIEUEQDV-UHFFFAOYSA-N 0.000 abstract 2
- LYUFSHWQUSNVQP-UHFFFAOYSA-N 8-(trifluoromethylsulfanyl)quinolin-4-amine Chemical class NC1=CC=NC2=C(C=CC=C12)SC(F)(F)F LYUFSHWQUSNVQP-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 229940102398 methyl anthranilate Drugs 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- RLOWWWKZYUNIDI-UHFFFAOYSA-N phosphinic chloride Chemical compound ClP=O RLOWWWKZYUNIDI-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7308677A FR2221126B2 (enExample) | 1973-03-12 | 1973-03-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1423932A true GB1423932A (en) | 1976-02-04 |
Family
ID=9116116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1101074A Expired GB1423932A (en) | 1973-03-12 | 1974-03-12 | 4-amino-quinolines |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE812108A (enExample) |
| CH (1) | CH590237A5 (enExample) |
| DE (1) | DE2411523A1 (enExample) |
| FR (1) | FR2221126B2 (enExample) |
| GB (1) | GB1423932A (enExample) |
| NL (1) | NL7403217A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2509728A1 (fr) * | 1981-07-17 | 1983-01-21 | Roussel Uclaf | Nouveaux derives de la quinoleine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
-
1973
- 1973-03-12 FR FR7308677A patent/FR2221126B2/fr not_active Expired
-
1974
- 1974-03-11 NL NL7403217A patent/NL7403217A/xx not_active Application Discontinuation
- 1974-03-11 BE BE141845A patent/BE812108A/xx unknown
- 1974-03-11 DE DE19742411523 patent/DE2411523A1/de not_active Ceased
- 1974-03-11 CH CH339374A patent/CH590237A5/xx not_active IP Right Cessation
- 1974-03-12 GB GB1101074A patent/GB1423932A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2221126A2 (enExample) | 1974-10-11 |
| BE812108A (fr) | 1974-09-11 |
| FR2221126B2 (enExample) | 1977-01-28 |
| NL7403217A (enExample) | 1974-09-16 |
| DE2411523A1 (de) | 1974-09-26 |
| CH590237A5 (enExample) | 1977-07-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |