GB1423664A - Prostaglandin compounds - Google Patents
Prostaglandin compoundsInfo
- Publication number
- GB1423664A GB1423664A GB4324173A GB4324173A GB1423664A GB 1423664 A GB1423664 A GB 1423664A GB 4324173 A GB4324173 A GB 4324173A GB 4324173 A GB4324173 A GB 4324173A GB 1423664 A GB1423664 A GB 1423664A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dimethyl
- pgf
- pge
- formulμ
- trans
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Prostaglandin compounds Chemical class 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 3
- 150000003180 prostaglandins Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 150000002170 ethers Chemical class 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- DHXVGJBLRPWPCS-UHFFFAOYSA-N Tetrahydropyran Chemical compound C1CCOCC1 DHXVGJBLRPWPCS-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 150000004702 methyl esters Chemical class 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 239000008016 pharmaceutical coating Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP47093012A JPS4949963A (fi) | 1972-09-16 | 1972-09-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1423664A true GB1423664A (en) | 1976-02-04 |
Family
ID=14070503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4324173A Expired GB1423664A (en) | 1972-09-16 | 1973-09-14 | Prostaglandin compounds |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS4949963A (fi) |
| AU (1) | AU6034273A (fi) |
| BE (1) | BE804898A (fi) |
| DE (1) | DE2346664A1 (fi) |
| FR (1) | FR2199981B1 (fi) |
| GB (1) | GB1423664A (fi) |
| ZA (1) | ZA737328B (fi) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4026927A (en) * | 1973-09-25 | 1977-05-31 | Yamanouchi Pharmaceutical Co., Ltd. | Novel prostaglandin derivatives |
| US4058665A (en) * | 1975-11-06 | 1977-11-15 | Yamanouchi Pharmaceutical Co., Ltd. | Novel 3,15-dilower alkyl PGE2 derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA72713B (en) * | 1971-02-26 | 1972-10-25 | Ici Ltd | Cyclopentane derivatives |
| JPS4864073A (fi) * | 1971-04-30 | 1973-09-05 | ||
| FR2134673A1 (en) * | 1971-04-30 | 1972-12-08 | Ono Pharmaceutical Co | Novel optically active isomers of prostaglandin analoguesof natural configuration useful as hypotensive agents, diuretics,contraceptives, for treating gastric ulcer and asthma, and forinhibiting platelet aggregation |
-
1972
- 1972-09-16 JP JP47093012A patent/JPS4949963A/ja active Pending
-
1973
- 1973-09-14 ZA ZA737328*A patent/ZA737328B/xx unknown
- 1973-09-14 GB GB4324173A patent/GB1423664A/en not_active Expired
- 1973-09-14 FR FR7333077A patent/FR2199981B1/fr not_active Expired
- 1973-09-14 AU AU60342/73A patent/AU6034273A/en not_active Expired
- 1973-09-14 BE BE135690A patent/BE804898A/xx unknown
- 1973-09-17 DE DE19732346664 patent/DE2346664A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4949963A (fi) | 1974-05-15 |
| FR2199981A1 (fi) | 1974-04-19 |
| ZA737328B (en) | 1974-08-28 |
| FR2199981B1 (fi) | 1977-07-15 |
| BE804898A (fr) | 1974-03-14 |
| DE2346664A1 (de) | 1974-04-11 |
| AU6034273A (en) | 1975-03-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |