GB1422768A - Sustained release tablets containing nicotinic acid and a process for the manufacture thereof - Google Patents
Sustained release tablets containing nicotinic acid and a process for the manufacture thereofInfo
- Publication number
- GB1422768A GB1422768A GB2353574A GB2353574A GB1422768A GB 1422768 A GB1422768 A GB 1422768A GB 2353574 A GB2353574 A GB 2353574A GB 2353574 A GB2353574 A GB 2353574A GB 1422768 A GB1422768 A GB 1422768A
- Authority
- GB
- United Kingdom
- Prior art keywords
- nicotinic acid
- sustained release
- tablets
- sustained
- lubricant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title abstract 8
- 229960003512 nicotinic acid Drugs 0.000 title abstract 4
- 235000001968 nicotinic acid Nutrition 0.000 title abstract 4
- 239000011664 nicotinic acid Substances 0.000 title abstract 4
- 239000007939 sustained release tablet Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000013268 sustained release Methods 0.000 abstract 4
- 239000012730 sustained-release form Substances 0.000 abstract 4
- 239000004615 ingredient Substances 0.000 abstract 3
- 239000003826 tablet Substances 0.000 abstract 3
- 239000011230 binding agent Substances 0.000 abstract 2
- 239000000314 lubricant Substances 0.000 abstract 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229920000945 Amylopectin Polymers 0.000 abstract 1
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- 229910021485 fumed silica Inorganic materials 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 239000008019 pharmaceutical lubricant Substances 0.000 abstract 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 235000003441 saturated fatty acids Nutrition 0.000 abstract 1
- 150000004671 saturated fatty acids Chemical class 0.000 abstract 1
- 239000000454 talc Substances 0.000 abstract 1
- 229910052623 talc Inorganic materials 0.000 abstract 1
- 239000003232 water-soluble binding agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36444373A | 1973-05-29 | 1973-05-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1422768A true GB1422768A (en) | 1976-01-28 |
Family
ID=23434551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2353574A Expired GB1422768A (en) | 1973-05-29 | 1974-05-28 | Sustained release tablets containing nicotinic acid and a process for the manufacture thereof |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS5031022A (enrdf_load_stackoverflow) |
| DE (1) | DE2425764A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2231365B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1422768A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2163648A (en) * | 1984-08-03 | 1986-03-05 | Nippon Shinyaku Co Ltd | Slow release preparations |
| US5853758A (en) * | 1992-01-13 | 1998-12-29 | Pfizer Inc. | Preparation of tablets of increased strength |
| EP1688143A3 (en) * | 1992-06-29 | 2009-11-11 | Kos Life Sciences, Inc. | Niacin-containing substained-release tablets and kits |
| WO2014179845A1 (en) * | 2013-05-09 | 2014-11-13 | Zeenar Enterprises Pty Ltd | Niacin formulation |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2904310A1 (de) * | 1979-02-05 | 1980-08-07 | Boehringer Mannheim Gmbh | Formlinge mit retardierter wirkstofffreisetzung und verfahren zu deren herstellung |
| JPS5974374U (ja) * | 1982-11-11 | 1984-05-19 | セイコーインスツルメンツ株式会社 | 携帯時計の文字板保持構造 |
| US4797288A (en) * | 1984-10-05 | 1989-01-10 | Warner-Lambert Company | Novel drug delivery system |
| US4828857A (en) * | 1984-10-05 | 1989-05-09 | Warner-Lambert Company | Novel sweetener delivery systems |
| US4804548A (en) * | 1984-10-05 | 1989-02-14 | Warner-Lambert Company | Novel sweetener delivery systems |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1617593A1 (de) * | 1965-10-12 | 1971-04-29 | Leo Pharm Prod Ltd | Verfahren zur Herstellung von Tabletten oder Pillen |
-
1974
- 1974-05-27 JP JP5890874A patent/JPS5031022A/ja active Pending
- 1974-05-27 FR FR7418230A patent/FR2231365B1/fr not_active Expired
- 1974-05-28 DE DE19742425764 patent/DE2425764A1/de active Pending
- 1974-05-28 GB GB2353574A patent/GB1422768A/en not_active Expired
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2163648A (en) * | 1984-08-03 | 1986-03-05 | Nippon Shinyaku Co Ltd | Slow release preparations |
| GB2163648B (en) * | 1984-08-03 | 1989-06-01 | Nippon Shinyaku Co Ltd | Pharmaceutical preparation and a method of making the same |
| US5853758A (en) * | 1992-01-13 | 1998-12-29 | Pfizer Inc. | Preparation of tablets of increased strength |
| EP1688143A3 (en) * | 1992-06-29 | 2009-11-11 | Kos Life Sciences, Inc. | Niacin-containing substained-release tablets and kits |
| WO2014179845A1 (en) * | 2013-05-09 | 2014-11-13 | Zeenar Enterprises Pty Ltd | Niacin formulation |
| US20160081996A1 (en) * | 2013-05-09 | 2016-03-24 | Zeenar Enterprises Pty Ltd | Niacin Formulation |
| EP3016655A4 (en) * | 2013-05-09 | 2017-04-12 | Zeenar Enterprises Pty Ltd | Niacin formulation |
| US10105358B2 (en) | 2013-05-09 | 2018-10-23 | Zeenar Enterprises Pty Ltd | Niacin formulation |
| US10335403B2 (en) | 2013-05-09 | 2019-07-02 | Zeenar Enterprise Pty Ltd | Niacin formulation |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5031022A (enrdf_load_stackoverflow) | 1975-03-27 |
| FR2231365A1 (enrdf_load_stackoverflow) | 1974-12-27 |
| FR2231365B1 (enrdf_load_stackoverflow) | 1977-11-04 |
| DE2425764A1 (de) | 1975-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |