GB1421999A - Heterocyclic containing sulphoxides - Google Patents
Heterocyclic containing sulphoxidesInfo
- Publication number
- GB1421999A GB1421999A GB4925773A GB4925773A GB1421999A GB 1421999 A GB1421999 A GB 1421999A GB 4925773 A GB4925773 A GB 4925773A GB 4925773 A GB4925773 A GB 4925773A GB 1421999 A GB1421999 A GB 1421999A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydrogen
- sulphoxides
- sulphur
- feb
- atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000623 heterocyclic group Chemical group 0.000 title abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 239000005864 Sulphur Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004429 atom Chemical group 0.000 abstract 2
- VFWUYASTZCOUKN-UHFFFAOYSA-N 2-[(5-methyl-1h-imidazol-4-yl)methylsulfanyl]ethanamine;dihydrochloride Chemical compound Cl.Cl.CC=1N=CNC=1CSCCN VFWUYASTZCOUKN-UHFFFAOYSA-N 0.000 abstract 1
- 102000003710 Histamine H2 Receptors Human genes 0.000 abstract 1
- 108090000050 Histamine H2 Receptors Proteins 0.000 abstract 1
- ATTZFSUZZUNHBP-UHFFFAOYSA-N Piperonyl sulfoxide Chemical compound CCCCCCCCS(=O)C(C)CC1=CC=C2OCOC2=C1 ATTZFSUZZUNHBP-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/26—Radicals substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pyrrole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (26)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4925773A GB1421999A (en) | 1973-02-08 | 1973-10-23 | Heterocyclic containing sulphoxides |
| AR25633374A AR206793A1 (es) | 1973-02-08 | 1974-01-01 | Procedimiento para la produccion de(n-ciano-n'-alquilguanidinoetil)metilsulfoxidos |
| AR252233A AR207559A1 (es) | 1973-02-08 | 1974-01-01 | Procedimiento para la preparacion de (n'-alquiltioureidoetil)metilsulfoxidos heterociclicos) |
| AR256332A AR206792A1 (es) | 1973-02-08 | 1974-01-01 | Procedimiento para la preparacion de (n-ciano-n'-alquilguanidinoetil)metilsulfoxidos |
| IE59/74A IE38730B1 (en) | 1973-02-08 | 1974-01-10 | Heterocyclic containing sulphoxides |
| IL44030A IL44030A (en) | 1973-02-08 | 1974-01-20 | Imidazolymethyl and thiazolylmethyl sulphoxides and process for their preparation |
| IN144/CAL/74A IN139091B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-02-08 | 1974-01-21 | |
| AU64862/74A AU475265B2 (en) | 1973-01-08 | 1974-01-24 | Sulphoxides |
| US05/436,285 US3932443A (en) | 1973-02-08 | 1974-01-24 | Sulphoxides |
| ZM17/74A ZM1774A1 (en) | 1973-02-08 | 1974-01-25 | Sulphoxides |
| CA190,959A CA1018983A (en) | 1973-02-08 | 1974-01-25 | Sulphoxides |
| EG24A EG11468A (en) | 1973-02-08 | 1974-01-28 | Process for the preparation of sulphoxides and pharmaceutical compositions comprising them |
| PH15461A PH10649A (en) | 1973-02-08 | 1974-01-31 | Sulphoxide derivatives and pharmaceutical compositions thereof |
| SE7401581A SE409707B (sv) | 1973-02-08 | 1974-02-06 | Forfarande for framstellning av sulfoxider, vilka er antagonister mot vissa verkningar av histamin |
| JP49015816A JPS5761740B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-02-08 | 1974-02-07 | |
| FR7404098A FR2216993B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-02-08 | 1974-02-07 | |
| CH179974A CH601323A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-02-08 | 1974-02-08 | |
| NL7401773A NL7401773A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-02-08 | 1974-02-08 | |
| CH450377A CH598268A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-02-08 | 1974-02-08 | |
| ES423056A ES423056A1 (es) | 1973-02-08 | 1974-02-08 | Procedimiento para la produccion de sulfoxidos. |
| DE19742406166 DE2406166A1 (de) | 1973-02-08 | 1974-02-08 | Sulfoxide, ihre salze mit saeuren, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US05/627,418 US3979398A (en) | 1973-02-08 | 1975-10-30 | Sulphoxides |
| US05/689,013 US4056620A (en) | 1973-02-08 | 1976-05-24 | Sulphoxides |
| US05/960,364 US4255425A (en) | 1973-02-08 | 1978-11-13 | Sulphoxides |
| US06/197,430 US4338328A (en) | 1973-02-08 | 1980-10-16 | Sulphoxides of heterocyclicthioalkylthioureas, ureas and guanidines |
| US06/362,220 US4413130A (en) | 1973-02-08 | 1982-03-26 | Sulphoxides |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB615373 | 1973-02-08 | ||
| GB4925773A GB1421999A (en) | 1973-02-08 | 1973-10-23 | Heterocyclic containing sulphoxides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1421999A true GB1421999A (en) | 1976-01-21 |
Family
ID=26240476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4925773A Expired GB1421999A (en) | 1973-01-08 | 1973-10-23 | Heterocyclic containing sulphoxides |
Country Status (18)
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4165378A (en) | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidine derivatives of imidazoles and thiazoles |
| US4165377A (en) | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidino imidazoles and thiazoles |
| US4242350A (en) | 1978-05-24 | 1980-12-30 | Imperial Chemical Industries Limited | Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them |
| US4242351A (en) * | 1979-05-07 | 1980-12-30 | Imperial Chemical Industries Limited | Antisecretory oxadiazoles and pharmaceutical compositions containing them |
| US4315009A (en) | 1978-01-18 | 1982-02-09 | Imperial Chemical Industries Limited | Antisecretory guanidine derivatives and pharmaceutical compositions containing them |
| US4342765A (en) | 1979-01-18 | 1982-08-03 | Imperial Chemical Industries Limited | Guanidine derivatives and pharmaceutical compositions containing them |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
| US4287198A (en) * | 1971-03-09 | 1981-09-01 | Smith Kline & French Laboratories Limited | Pharmacologically active guanidine compounds |
| US4221802A (en) * | 1972-02-03 | 1980-09-09 | Smith Kline & French Laboratories Limited | Pharmacologically active guanidine compounds for inhibiting H-2 histamine receptors |
| US4070475A (en) * | 1972-02-03 | 1978-01-24 | Smith Kline & French Laboratories Limited | Pharmacologically active guanidine compounds as H-2 histamine receptor inhibitors |
| GB1421999A (en) * | 1973-02-08 | 1976-01-21 | Smith Kline French Lab | Heterocyclic containing sulphoxides |
| GB1565205A (en) * | 1975-07-31 | 1980-04-16 | Smith Kline French Lab | Heterocyclic sulphoxides |
| US4070472A (en) * | 1974-02-07 | 1978-01-24 | Smith Kline & French Laboratories Limited | Guanidino, thioureido, isothioureido and nitrovinylamino derivatives of pyridine |
| US4090026A (en) * | 1974-09-02 | 1978-05-16 | Smith Kline & French Laboratories Limited | Certain nitrogen heterocyclic isothiocyanate esters |
| US4151289A (en) * | 1975-01-22 | 1979-04-24 | Smith Kline & French Laboratories Limited | Nitromethylene amidino derivatives containing imidazole groups |
| GB1574214A (en) | 1976-03-11 | 1980-09-03 | Smith Kline French Lab | Amidines |
| US4200760A (en) * | 1978-09-26 | 1980-04-29 | Bristol-Myers Company | Imidazolylalkylthioalkylamino-ethylene derivatives |
| US4220654A (en) * | 1979-06-04 | 1980-09-02 | Merck & Co., Inc. | Cyclic imidazole cyanoguanidines |
| DE3048487A1 (de) * | 1980-12-22 | 1982-07-29 | Cassella Ag, 6000 Frankfurt | Basisch substituierte pyridazine, ihre herstellung und ihre verwendung |
| US4528378A (en) * | 1982-03-29 | 1985-07-09 | Bristol-Myers Company | Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity |
| US4528375A (en) * | 1982-03-29 | 1985-07-09 | Bristol-Myers Company | Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity |
| US4528377A (en) * | 1982-03-29 | 1985-07-09 | Bristol-Myers Company | Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity |
| US4520025A (en) * | 1982-07-21 | 1985-05-28 | William H. Rorer, Inc. | Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses |
| US4543352A (en) * | 1983-04-29 | 1985-09-24 | William H. Rorer, Inc. | Naphthalene aminoalkylene ethers and thioethers, and their pharmaceutical uses |
| US5166214A (en) * | 1988-12-05 | 1992-11-24 | Du Pont Merck Pharmaceutical Company | Use of imidazoles for the treatment of atherosclerosis |
| US5179117A (en) * | 1991-12-20 | 1993-01-12 | Du Pont Merck Pharmaceutical Company | Antihypercholesterolemic 2-substituted imidazoles |
| US5364875A (en) * | 1992-05-11 | 1994-11-15 | The Du Pont Merck Pharmaceutical Company | Imidazoles linked to bicyclic heterocyclic groups for the treatment of atherosclerosis |
| US5310748A (en) * | 1992-05-11 | 1994-05-10 | The Du Pont Merck Pharmaceutical Company | Imidazoles for the treatment of atherosclerosis |
| US5358946A (en) * | 1992-05-29 | 1994-10-25 | The Du Pont Merck Pharmaceutical Company | Heterocycle-substituted amides, carbamates and ureas as agents for the treatment of atherosclerosis |
| US5883252A (en) * | 1996-01-26 | 1999-03-16 | Vertex Pharmaceuticals Incorporated | Aspartyl protease inhibitors |
| US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE758146A (fr) * | 1969-10-29 | 1971-04-28 | Smith Kline French Lab | Derives de l'amidine |
| US3808336A (en) * | 1970-06-25 | 1974-04-30 | Smithkline Corp | Pharmaceutical compositions and methods of inhibiting histamine activity with thiourea derivatives |
| GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
| US3905984A (en) * | 1971-03-09 | 1975-09-16 | Smith Kline French Lab | Pyridyl substituted thioalkyl-and oxyalkyl-thioureas and ureas |
| US3950353A (en) * | 1971-03-09 | 1976-04-13 | Smith Kline & French Laboratories Limited | Pharmacologically active thiourea and urea compounds |
| GB1397436A (en) * | 1972-09-05 | 1975-06-11 | Smith Kline French Lab | Heterocyclic n-cyanoguinidines |
| US4000296A (en) * | 1972-09-05 | 1976-12-28 | Smith Kline & French Laboratories Limited | Imidazole alkylguanidine compounds |
| GB1421999A (en) * | 1973-02-08 | 1976-01-21 | Smith Kline French Lab | Heterocyclic containing sulphoxides |
| US3979398A (en) * | 1973-02-08 | 1976-09-07 | Smith Kline & French Laboratories Limited | Sulphoxides |
| US4140783A (en) * | 1976-05-24 | 1979-02-20 | Smith Kline & French Laboratories Limited | Isothiazole and isoxazole sulphoxides |
-
1973
- 1973-10-23 GB GB4925773A patent/GB1421999A/en not_active Expired
-
1974
- 1974-01-01 AR AR256332A patent/AR206792A1/es active
- 1974-01-01 AR AR252233A patent/AR207559A1/es active
- 1974-01-10 IE IE59/74A patent/IE38730B1/xx unknown
- 1974-01-20 IL IL44030A patent/IL44030A/xx unknown
- 1974-01-21 IN IN144/CAL/74A patent/IN139091B/en unknown
- 1974-01-24 AU AU64862/74A patent/AU475265B2/en not_active Expired
- 1974-01-24 US US05/436,285 patent/US3932443A/en not_active Expired - Lifetime
- 1974-01-25 CA CA190,959A patent/CA1018983A/en not_active Expired
- 1974-01-25 ZM ZM17/74A patent/ZM1774A1/xx unknown
- 1974-01-28 EG EG24A patent/EG11468A/xx active
- 1974-01-31 PH PH15461A patent/PH10649A/en unknown
- 1974-02-06 SE SE7401581A patent/SE409707B/xx unknown
- 1974-02-07 JP JP49015816A patent/JPS5761740B2/ja not_active Expired
- 1974-02-07 FR FR7404098A patent/FR2216993B1/fr not_active Expired
- 1974-02-08 CH CH450377A patent/CH598268A5/xx not_active IP Right Cessation
- 1974-02-08 NL NL7401773A patent/NL7401773A/xx not_active Application Discontinuation
- 1974-02-08 DE DE19742406166 patent/DE2406166A1/de not_active Withdrawn
- 1974-02-08 ES ES423056A patent/ES423056A1/es not_active Expired
- 1974-02-08 CH CH179974A patent/CH601323A5/xx not_active IP Right Cessation
-
1978
- 1978-11-13 US US05/960,364 patent/US4255425A/en not_active Expired - Lifetime
-
1980
- 1980-10-16 US US06/197,430 patent/US4338328A/en not_active Expired - Lifetime
-
1982
- 1982-03-26 US US06/362,220 patent/US4413130A/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4165378A (en) | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidine derivatives of imidazoles and thiazoles |
| US4165377A (en) | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidino imidazoles and thiazoles |
| US4234735A (en) | 1977-04-20 | 1980-11-18 | Imperial Chemical Industries Limited | Guanidino imidazoles and thiazoles |
| US4262126A (en) | 1977-04-20 | 1981-04-14 | Imperial Chemical Industries Limited | Guanidine derivatives of imidazoles and thiazoles |
| US4315009A (en) | 1978-01-18 | 1982-02-09 | Imperial Chemical Industries Limited | Antisecretory guanidine derivatives and pharmaceutical compositions containing them |
| US4242350A (en) | 1978-05-24 | 1980-12-30 | Imperial Chemical Industries Limited | Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them |
| US4342765A (en) | 1979-01-18 | 1982-08-03 | Imperial Chemical Industries Limited | Guanidine derivatives and pharmaceutical compositions containing them |
| US4242351A (en) * | 1979-05-07 | 1980-12-30 | Imperial Chemical Industries Limited | Antisecretory oxadiazoles and pharmaceutical compositions containing them |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |