GB1421554A - Process for the stereoselective production of intermediates in the synthesis of pgea and derivatives - Google Patents
Process for the stereoselective production of intermediates in the synthesis of pgea and derivativesInfo
- Publication number
- GB1421554A GB1421554A GB5395174A GB5395174A GB1421554A GB 1421554 A GB1421554 A GB 1421554A GB 5395174 A GB5395174 A GB 5395174A GB 5395174 A GB5395174 A GB 5395174A GB 1421554 A GB1421554 A GB 1421554A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pgea
- intermediates
- synthesis
- derivatives
- stereoselective production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000000707 stereoselective effect Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 125000004187 tetrahydropyran-2-yl group Chemical group [H]C1([H])OC([H])(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000003944 tolyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23579472A | 1972-03-17 | 1972-03-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1421554A true GB1421554A (en) | 1976-01-21 |
Family
ID=22886940
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1001073A Expired GB1421553A (en) | 1972-03-17 | 1973-03-01 | Process for the production of prostaglandins |
| GB5395174A Expired GB1421554A (en) | 1972-03-17 | 1973-03-01 | Process for the stereoselective production of intermediates in the synthesis of pgea and derivatives |
| GB5395274A Expired GB1421555A (en) | 1972-03-17 | 1973-03-01 | Process for the stereoselective production of intermediates in the synthesis of pge1 and derivatives |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1001073A Expired GB1421553A (en) | 1972-03-17 | 1973-03-01 | Process for the production of prostaglandins |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5395274A Expired GB1421555A (en) | 1972-03-17 | 1973-03-01 | Process for the stereoselective production of intermediates in the synthesis of pge1 and derivatives |
Country Status (7)
| Country | Link |
|---|---|
| JP (3) | JPS5710105B2 (es) |
| CH (3) | CH579538A5 (es) |
| DE (1) | DE2310556A1 (es) |
| FR (2) | FR2176768B1 (es) |
| GB (3) | GB1421553A (es) |
| HU (2) | HU170071B (es) |
| NL (1) | NL7303705A (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51100045A (en) * | 1975-02-27 | 1976-09-03 | Sagami Chem Res | 33 horumirushikuropentanonjudotaino seizohoho |
| JPS61116408U (es) * | 1984-12-28 | 1986-07-23 | ||
| ES2110499T3 (es) * | 1991-06-19 | 1998-02-16 | Shionogi & Co | Intermediario opticamente activo y su produccion. |
| JP4648340B2 (ja) * | 2006-02-07 | 2011-03-09 | 株式会社アールテック・ウエノ | １５−ケトプロスタグランジンｅ誘導体の製造法 |
| CN102101835B (zh) * | 2009-12-16 | 2015-07-22 | 武汉启瑞药业有限公司 | 前列腺素衍生物及其中间体的制备方法 |
-
1973
- 1973-03-01 GB GB1001073A patent/GB1421553A/en not_active Expired
- 1973-03-01 GB GB5395174A patent/GB1421554A/en not_active Expired
- 1973-03-01 GB GB5395274A patent/GB1421555A/en not_active Expired
- 1973-03-02 DE DE19732310556 patent/DE2310556A1/de not_active Withdrawn
- 1973-03-09 CH CH353773A patent/CH579538A5/xx not_active IP Right Cessation
- 1973-03-09 CH CH1088976A patent/CH597179A5/xx not_active IP Right Cessation
- 1973-03-09 CH CH361176A patent/CH583698A5/xx not_active IP Right Cessation
- 1973-03-09 HU HUSE1812A patent/HU170071B/hu unknown
- 1973-03-09 HU HUSE1811A patent/HU169931B/hu unknown
- 1973-03-15 FR FR7309411A patent/FR2176768B1/fr not_active Expired
- 1973-03-16 NL NL7303705A patent/NL7303705A/xx not_active Application Discontinuation
- 1973-03-16 JP JP3079073A patent/JPS5710105B2/ja not_active Expired
- 1973-08-24 FR FR7330818A patent/FR2202074B1/fr not_active Expired
-
1981
- 1981-08-21 JP JP56131428A patent/JPS5781457A/ja active Pending
- 1981-08-21 JP JP56131427A patent/JPS5781456A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GB1421553A (en) | 1976-01-21 |
| CH597179A5 (es) | 1978-03-31 |
| JPS5710105B2 (es) | 1982-02-24 |
| HU170071B (es) | 1977-03-28 |
| HU169931B (es) | 1977-02-28 |
| JPS5781456A (en) | 1982-05-21 |
| NL7303705A (es) | 1973-09-19 |
| CH583698A5 (es) | 1977-01-14 |
| FR2202074B1 (es) | 1977-02-25 |
| JPS4918852A (es) | 1974-02-19 |
| CH579538A5 (es) | 1976-09-15 |
| GB1421555A (en) | 1976-01-21 |
| FR2176768A1 (es) | 1973-11-02 |
| DE2310556A1 (de) | 1973-09-27 |
| JPS5781457A (en) | 1982-05-21 |
| FR2202074A1 (es) | 1974-05-03 |
| FR2176768B1 (es) | 1978-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |