GB1419061A - Two-chamber syringe - Google Patents

Two-chamber syringe

Info

Publication number
GB1419061A
GB1419061A GB5351172A GB5351172A GB1419061A GB 1419061 A GB1419061 A GB 1419061A GB 5351172 A GB5351172 A GB 5351172A GB 5351172 A GB5351172 A GB 5351172A GB 1419061 A GB1419061 A GB 1419061A
Authority
GB
United Kingdom
Prior art keywords
connector
syringe body
container
solvent
membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5351172A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of GB1419061A publication Critical patent/GB1419061A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2051—Connecting means having tap means, e.g. tap means activated by sliding

Abstract

1419061 Surgical syringes HOECHST AG 20 Nov 1972 [20 Nov 1971] 53511/72 Heading A5R A two-chamber syringe comprises a hollow syringe body 1 attached to a solvent container 5 having a slidable piston 6 therein, and a hollow connector 3 attached to. the neck of a medicament container 2, the arrangement being such that relative axial movement of the syringe body and the connector causes a cannula 11 mounted on a support member 10 axially movable in the bore 9 of the syringe body to first pierce a membrane 16 of the connector and subsequently pierce a membrane 13 of the syringe body. As shown the syringe body and the connector are screw-threaded and respectively provided with an annular groove 17 and a raised bead to prevent premature perforation of the membranes. In alternative forms the connector may have a securing ring or be joined to the syringe body by spot welding to prevent premature perforation. The solvent and medicament containers are respectively attached to the syringe body and the connector by the engagement of a bead, e.g. the bead 4, with a flanged rim, e.g. the rim 21. In alternative forms the syringe body or connector is deformed into engagement with a flange of the respective container and may engage a ring beneath the flange. The solvent and medicament containers are each sealed by a rubber stopper, e.g. the stopper 8, and an aluminium cap, e.g. the cap 7, having a central aperture. In use, the connector is screwed onto the syringe body until the cannula, which is retained in the bore 9 by engagement of an annular projection 12 with a groove in the bore, pierces the membrane 16. After a shoulder A of the support member 10 has abutted a shoulder B of the connector, further rotation of the connector causes the cannula to pierce the membrane 13. A metal ring 15 is provided on the lower surface of the end 14 of the support member. Pressure exerted on a piston rod 19 causes the solvent to be conveyed to the medicament container and form a solution which is reconveyed to the solvent container by pulling back the piston 6. Subsequently the connector is removed and a needle 20 stored in the interior of the piston rod is attached to the frusto-conical end 14 of the support member. A finger support 22 is provided on the solvent container. The support member may be provided with longitudinal fins to ensure the cannula pierces the container seals centrally. The membrane of the syringe body may be in the form of a tightly fitting insert.
GB5351172A 1971-11-20 1972-11-20 Two-chamber syringe Expired GB1419061A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2157582A DE2157582A1 (en) 1971-11-20 1971-11-20 TWO-CHAMBER SYRINGE

Publications (1)

Publication Number Publication Date
GB1419061A true GB1419061A (en) 1975-12-24

Family

ID=5825627

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5351172A Expired GB1419061A (en) 1971-11-20 1972-11-20 Two-chamber syringe

Country Status (11)

Country Link
AT (1) AT350709B (en)
BE (1) BE791634A (en)
CH (1) CH556171A (en)
DE (1) DE2157582A1 (en)
ES (1) ES408572A1 (en)
FR (1) FR2160668B1 (en)
GB (1) GB1419061A (en)
IE (1) IE37161B1 (en)
IT (1) IT971014B (en)
LU (1) LU66493A1 (en)
NL (1) NL167598C (en)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0882441A2 (en) * 1997-06-03 1998-12-09 TAKEDA CHEMICAL INDUSTRIES, Ltd. Dual-chamber injection system and connector used therefor
US5891129A (en) * 1997-02-28 1999-04-06 Abbott Laboratories Container cap assembly having an enclosed penetrator
US5924584A (en) * 1997-02-28 1999-07-20 Abbott Laboratories Container closure with a frangible seal and a connector for a fluid transfer device
WO2005011781A1 (en) * 2003-07-22 2005-02-10 Barry Peter Liversidge Medical needle system
EP1415636A3 (en) * 1998-09-15 2005-07-27 Baxter International Inc. Sliding reconstitution device for a diluent container
EP2014322A1 (en) * 2006-04-18 2009-01-14 Zhongshan Botai Pharmaceutic Instruments Co., Ltd. A sterile drug-mixing syringe
EP2419161A2 (en) * 2009-04-15 2012-02-22 Becton, Dickinson and Company Fixturing member and device for permitting mixing in a pen injector
US8226627B2 (en) 1998-09-15 2012-07-24 Baxter International Inc. Reconstitution assembly, locking device and method for a diluent container
US8562582B2 (en) 2006-05-25 2013-10-22 Bayer Healthcare Llc Reconstitution device
US8721612B2 (en) 2010-12-17 2014-05-13 Hospira, Inc. System and method for intermixing the contents of two containers
US8801689B2 (en) 2007-08-01 2014-08-12 Hospira, Inc. Medicament admixing system
US8834444B2 (en) 2011-10-03 2014-09-16 Hospira, Inc. System and method for mixing the contents of two containers
EP3113812A4 (en) * 2014-03-05 2018-03-07 Yukon Medical, LLC Pre-filled diluent syringe vial adapter
WO2021123760A1 (en) * 2019-12-17 2021-06-24 Oribiotech Ltd A connector

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2618763B2 (en) * 1972-06-13 1989-12-15 Semco Sam Emballage Conditionn PACKAGING FOR EXTREMPORANEOUS PREPARATIONS
FR2188565A5 (en) * 1972-06-13 1974-01-18 Semco Emballage Conditio
NL173477C (en) * 1974-09-12 1984-02-01 Duphar Int Res INJECTION SYRINGE WITH TELESCOPIC BODY BETWEEN CARTRIDGE AND MEDICINE BOTTLE.
DE7916475U1 (en) * 1979-06-08 1979-10-18 Hoechst Ag, 6000 Frankfurt Spray applicator
US4591049A (en) * 1984-01-16 1986-05-27 Kidde, Inc. Hermetically sealed two-component mixing system
SE8501656D0 (en) * 1985-04-03 1985-04-03 Mediplast Ab OVERFORINGSANORDNING
EP0252645A3 (en) * 1986-07-09 1988-05-25 Erbamont, Inc. Method and apparatus for purging a syringe
EP0283629B1 (en) * 1987-03-24 1991-12-18 Semco Packaging for extemporaneous preparations
EP0351643A3 (en) * 1988-07-18 1990-04-11 Becton, Dickinson and Company Universal safety inoculation devices
US4898209A (en) * 1988-09-27 1990-02-06 Baxter International Inc. Sliding reconstitution device with seal
FR2638721B1 (en) * 1988-11-09 1991-03-15 Lyotec DEVICE FOR EXTREMPORANEOUS PREPARATIONS BY MIXING THE CONTENTS OF TWO SEPARATE BOTTLES
WO1994000094A1 (en) * 1992-06-22 1994-01-06 Mary Therese Purcell A reconstitution device
CA2274290A1 (en) * 1999-06-09 2000-12-09 Duoject Medical Systems Inc. Delivery system for multi-component pharmaceuticals, and prefilled protosyringe for use therein
US6253804B1 (en) * 1999-11-05 2001-07-03 Minimed Inc. Needle safe transfer guard
US6453956B2 (en) 1999-11-05 2002-09-24 Medtronic Minimed, Inc. Needle safe transfer guard

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3336924A (en) * 1964-02-20 1967-08-22 Sarnoff Two compartment syringe package
US3392726A (en) * 1965-08-09 1968-07-16 Upjohn Co Combination syringe and vial container

Cited By (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891129A (en) * 1997-02-28 1999-04-06 Abbott Laboratories Container cap assembly having an enclosed penetrator
US5924584A (en) * 1997-02-28 1999-07-20 Abbott Laboratories Container closure with a frangible seal and a connector for a fluid transfer device
US5954104A (en) * 1997-02-28 1999-09-21 Abbott Laboratories Container cap assembly having an enclosed penetrator
US6524295B2 (en) 1997-02-28 2003-02-25 Abbott Laboratories Container cap assembly having an enclosed penetrator
US6610041B2 (en) 1997-02-28 2003-08-26 Abbott Laboratories Penetrator for a container occluded by a stopper
US6635043B2 (en) 1997-02-28 2003-10-21 Abbott Laboratories Container cap assembly having an enclosed penetrator
EP0882441A2 (en) * 1997-06-03 1998-12-09 TAKEDA CHEMICAL INDUSTRIES, Ltd. Dual-chamber injection system and connector used therefor
EP0882441A3 (en) * 1997-06-03 1999-02-24 TAKEDA CHEMICAL INDUSTRIES, Ltd. Dual-chamber injection system and connector used therefor
US6224568B1 (en) 1997-06-03 2001-05-01 Takeda Chemical Industries, Ltd. Dual-chamber type injector and connector used therefor
EP1415636A3 (en) * 1998-09-15 2005-07-27 Baxter International Inc. Sliding reconstitution device for a diluent container
US8226627B2 (en) 1998-09-15 2012-07-24 Baxter International Inc. Reconstitution assembly, locking device and method for a diluent container
WO2005011781A1 (en) * 2003-07-22 2005-02-10 Barry Peter Liversidge Medical needle system
EP2014322A1 (en) * 2006-04-18 2009-01-14 Zhongshan Botai Pharmaceutic Instruments Co., Ltd. A sterile drug-mixing syringe
EP2014322A4 (en) * 2006-04-18 2012-09-26 Zhongshan Botai Pharmaceutic Instr Co Ltd A sterile drug-mixing syringe
US9522098B2 (en) 2006-05-25 2016-12-20 Bayer Healthcare, Llc Reconstitution device
US8562582B2 (en) 2006-05-25 2013-10-22 Bayer Healthcare Llc Reconstitution device
US9198832B2 (en) 2007-08-01 2015-12-01 Hospira, Inc. Medicament admixing system
US9205026B2 (en) 2007-08-01 2015-12-08 Hospira, Inc. Medicament admixing system
US9205025B2 (en) 2007-08-01 2015-12-08 Hospira, Inc. Medicament admixing system
US8801689B2 (en) 2007-08-01 2014-08-12 Hospira, Inc. Medicament admixing system
US9381136B2 (en) 2009-04-15 2016-07-05 Becton, Dickinson And Company Fixturing member and device for permitting mixing in a pen injector
EP2419161A4 (en) * 2009-04-15 2013-11-27 Becton Dickinson Co Fixturing member and device for permitting mixing in a pen injector
CN106333854B (en) * 2009-04-15 2019-08-30 贝克顿·迪金森公司 For being allowed in the mixed fixation member and device in pen-type injector
CN106333854A (en) * 2009-04-15 2017-01-18 贝克顿·迪金森公司 Fixturing member and device for permitting mixing in a pen injector
EP2419161A2 (en) * 2009-04-15 2012-02-22 Becton, Dickinson and Company Fixturing member and device for permitting mixing in a pen injector
CN102448512A (en) * 2009-04-15 2012-05-09 贝克顿·迪金森公司 Fixturing member and device for permitting mixing in a pen injector
US8721612B2 (en) 2010-12-17 2014-05-13 Hospira, Inc. System and method for intermixing the contents of two containers
US9610223B2 (en) 2010-12-17 2017-04-04 Hospira, Inc. System and method for intermixing the contents of two containers
US8882739B2 (en) 2011-10-03 2014-11-11 Hospira, Inc. System and method for mixing the contents of two containers
US8834444B2 (en) 2011-10-03 2014-09-16 Hospira, Inc. System and method for mixing the contents of two containers
US9079686B2 (en) 2011-10-03 2015-07-14 Hospira, Inc. Port assembly for mixing the contents of two containers
US8911421B2 (en) 2011-10-03 2014-12-16 Hospira, Inc. System and method for mixing the contents of two containers
EP3113812A4 (en) * 2014-03-05 2018-03-07 Yukon Medical, LLC Pre-filled diluent syringe vial adapter
EP3581225A1 (en) * 2014-03-05 2019-12-18 Yukon Medical, LLC Pre-filled diluent syringe vial adapter
US10813837B2 (en) 2014-03-05 2020-10-27 Yukon Medical, Llc Pre-filled diluent syringe vial adapter
WO2021123760A1 (en) * 2019-12-17 2021-06-24 Oribiotech Ltd A connector
GB2590523A (en) * 2019-12-17 2021-06-30 Oribiotech Ltd A connector
GB2590523B (en) * 2019-12-17 2021-12-15 Oribiotech Ltd A connector
US11505776B2 (en) 2019-12-17 2022-11-22 Oribiotech Ltd Connector

Also Published As

Publication number Publication date
IE37161L (en) 1973-05-20
NL167598C (en) 1982-01-18
CH556171A (en) 1974-11-29
FR2160668A1 (en) 1973-06-29
NL7215451A (en) 1973-05-22
IE37161B1 (en) 1977-05-25
ATA981572A (en) 1978-11-15
DE2157582A1 (en) 1973-05-30
LU66493A1 (en) 1974-06-21
AT350709B (en) 1979-06-11
FR2160668B1 (en) 1977-01-14
IT971014B (en) 1974-04-30
ES408572A1 (en) 1975-11-01
BE791634A (en) 1973-05-21

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee