GB1397298A - Prostaglandin derivatives - Google Patents
Prostaglandin derivativesInfo
- Publication number
- GB1397298A GB1397298A GB4532272A GB4532272A GB1397298A GB 1397298 A GB1397298 A GB 1397298A GB 4532272 A GB4532272 A GB 4532272A GB 4532272 A GB4532272 A GB 4532272A GB 1397298 A GB1397298 A GB 1397298A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- hydrolysing
- acetate
- prostaglandin derivatives
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003180 prostaglandins Chemical class 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 5
- -1 2- tetrahydropyranyl Chemical group 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 230000003301 hydrolyzing effect Effects 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- IKHGUXGNUITLKF-UHFFFAOYSA-N Acetaldehyde Chemical compound CC=O IKHGUXGNUITLKF-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- HUHXLHLWASNVDB-UHFFFAOYSA-N 2-(oxan-2-yloxy)oxane Chemical compound O1CCCCC1OC1OCCCC1 HUHXLHLWASNVDB-UHFFFAOYSA-N 0.000 abstract 1
- PNVSXXXXDDILIR-UHFFFAOYSA-N 2-[2-(hydroxymethyl)cyclopentyl]acetic acid Chemical compound OCC1CCCC1CC(O)=O PNVSXXXXDDILIR-UHFFFAOYSA-N 0.000 abstract 1
- SILGWNVZOMANQQ-UHFFFAOYSA-N 3-oxo-2-oxabicyclo[3.2.1]octane-8-carbaldehyde Chemical compound C(=O)C1C2OC(CC1CC2)=O SILGWNVZOMANQQ-UHFFFAOYSA-N 0.000 abstract 1
- VBGFIVXUWNQCHN-UHFFFAOYSA-N 8-(hydroxymethyl)-2-oxabicyclo[3.2.1]octan-3-one Chemical compound OCC1C2OC(CC1CC2)=O VBGFIVXUWNQCHN-UHFFFAOYSA-N 0.000 abstract 1
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 abstract 1
- 239000003929 acidic solution Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000005215 alkyl ethers Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 229910052796 boron Inorganic materials 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000002196 ecbolic effect Effects 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic
- C07C35/06—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7654671A JPS4839463A (enrdf_load_stackoverflow) | 1971-09-30 | 1971-09-30 | |
| JP47067342A JPS5146112B2 (enrdf_load_stackoverflow) | 1972-07-05 | 1972-07-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1397298A true GB1397298A (en) | 1975-06-11 |
Family
ID=26408535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4532272A Expired GB1397298A (en) | 1971-09-30 | 1972-10-02 | Prostaglandin derivatives |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE789407A (enrdf_load_stackoverflow) |
| CA (1) | CA973876A (enrdf_load_stackoverflow) |
| CH (1) | CH576440A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2248357A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2154726B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1397298A (enrdf_load_stackoverflow) |
| NL (1) | NL7213210A (enrdf_load_stackoverflow) |
| SE (1) | SE387339B (enrdf_load_stackoverflow) |
-
0
- BE BE789407D patent/BE789407A/xx unknown
-
1972
- 1972-09-26 CA CA152,552A patent/CA973876A/en not_active Expired
- 1972-09-27 SE SE1245972A patent/SE387339B/xx unknown
- 1972-09-29 NL NL7213210A patent/NL7213210A/xx not_active Application Discontinuation
- 1972-09-29 CH CH1427772A patent/CH576440A5/xx not_active IP Right Cessation
- 1972-09-29 FR FR7234500A patent/FR2154726B1/fr not_active Expired
- 1972-09-29 DE DE19722248357 patent/DE2248357A1/de active Pending
- 1972-10-02 GB GB4532272A patent/GB1397298A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA973876A (en) | 1975-09-02 |
| CH576440A5 (enrdf_load_stackoverflow) | 1976-06-15 |
| BE789407A (fr) | 1973-01-15 |
| DE2248357A1 (de) | 1973-04-05 |
| NL7213210A (enrdf_load_stackoverflow) | 1973-04-03 |
| SE387339B (sv) | 1976-09-06 |
| FR2154726A1 (enrdf_load_stackoverflow) | 1973-05-11 |
| FR2154726B1 (enrdf_load_stackoverflow) | 1976-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |