GB1392490A - Analytical process - Google Patents
Analytical processInfo
- Publication number
- GB1392490A GB1392490A GB5689172A GB5689172A GB1392490A GB 1392490 A GB1392490 A GB 1392490A GB 5689172 A GB5689172 A GB 5689172A GB 5689172 A GB5689172 A GB 5689172A GB 1392490 A GB1392490 A GB 1392490A
- Authority
- GB
- United Kingdom
- Prior art keywords
- reaction
- sample
- mixed
- rotor
- measurements
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/07—Centrifugal type cuvettes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/111666—Utilizing a centrifuge or compartmented rotor
Landscapes
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Optical Measuring Cells (AREA)
Abstract
1392490 Rotary photometric analyzers UNION CARBIDE CORP 8 Dec 1972 [9 Dec 1971] 56891/72 Heading G1A In a multiple sample photometric analyzer of the type in which the rotation of a rotor causes reagents and samples originally placed in separate radially aligned chambers to be mixed and transferred to analysis chambers, measurements are made of the mixed reagent and sample before any substantial reaction has occurred to provide reference levels which are stored in a memory and subtracted from the corresponding measurements made after the reaction is completed. As shown, Fig. 3, light from a lamp 50 passes through the cuvettes of a rotor 35 the rotation of which produces output pulses from a photomultiplier 60, the amplitude of each pulse depending on the optical density of the respective sample. The output pulses are applied via a logarithmic amplifier 61 to a peak detector 62 which is reset between pulses. The rotor is loaded with samples and reagents and then spun so that they are mixed and transferred to the peripheral cuvettes. Before any reaction can occur the optical density of each mixed sample is measured, converted to digital form and stored in a memory unit 68 to provide a reference level. After a suitable length of time during which the reaction occurs a further set of measurements are taken and the corresponding values stored in a memory unit 72. The reference level of each sample is subtracted from the corresponding measurement after the reaction and the resulting value recorded by a printer 77. A specific example relates to the determination of glucose in blood serum, the composition of the reagent being given.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20637971A | 1971-12-09 | 1971-12-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1392490A true GB1392490A (en) | 1975-04-30 |
Family
ID=22766112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5689172A Expired GB1392490A (en) | 1971-12-09 | 1972-12-08 | Analytical process |
Country Status (14)
Country | Link |
---|---|
US (1) | US3759666A (en) |
JP (1) | JPS5249758B2 (en) |
AR (1) | AR206681A1 (en) |
AU (1) | AU465200B2 (en) |
BE (1) | BE792516A (en) |
BR (1) | BR7208659D0 (en) |
CA (1) | CA969384A (en) |
CH (1) | CH553403A (en) |
FR (1) | FR2164399A5 (en) |
GB (1) | GB1392490A (en) |
IL (1) | IL41040A (en) |
IT (1) | IT988366B (en) |
NL (1) | NL7216731A (en) |
SE (1) | SE406125B (en) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3856470A (en) * | 1973-01-10 | 1974-12-24 | Baxter Laboratories Inc | Rotor apparatus |
US3864089A (en) * | 1973-12-10 | 1975-02-04 | Atomic Energy Commission | Multiple-sample rotor assembly for blood fraction preparation |
US4007007A (en) * | 1974-02-22 | 1977-02-08 | Hans Otto Ernst Gazda | Apparatus for decontaminating liquids of bacteria |
US3953172A (en) * | 1974-05-10 | 1976-04-27 | Union Carbide Corporation | Method and apparatus for assaying liquid materials |
CH588700A5 (en) * | 1975-02-28 | 1977-06-15 | Hoffmann La Roche | |
US4123173A (en) * | 1976-06-09 | 1978-10-31 | Electro-Nucleonics, Inc. | Rotatable flexible cuvette arrays |
US4135883A (en) * | 1977-08-29 | 1979-01-23 | Bio-Dynamics Inc. | Blood analyzer system |
US4226531A (en) * | 1977-08-29 | 1980-10-07 | Instrumentation Laboratory Inc. | Disposable multi-cuvette rotor |
US4239853A (en) * | 1979-01-22 | 1980-12-16 | Bradley Rex L | Antibiotic testing method and apparatus having a channelized reservoir |
US4314970A (en) * | 1980-08-27 | 1982-02-09 | Instrumentation Laboratory Inc. | Analysis system |
DE3044385A1 (en) * | 1980-11-25 | 1982-06-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | METHOD FOR CARRYING OUT ANALYTICAL PROVISIONS AND ROTOR INSERT ELEMENT SUITABLE FOR THIS |
DE3044372A1 (en) * | 1980-11-25 | 1982-07-08 | Boehringer Mannheim Gmbh, 6800 Mannheim | ROTOR UNIT WITH INSERT ELEMENTS FOR A CENTRIFUGAL ANALYZER |
US4373812A (en) * | 1981-03-25 | 1983-02-15 | Instrumentation Laboratory Inc. | Cuvette assembly |
US4390499A (en) * | 1981-08-13 | 1983-06-28 | International Business Machines Corporation | Chemical analysis system including a test package and rotor combination |
US4470954A (en) * | 1983-06-13 | 1984-09-11 | Chiknas Steven G | Rotor or carrier for centrifugal analyzer and bead washer |
US4580896A (en) * | 1983-11-07 | 1986-04-08 | Allied Corporation | Multicuvette centrifugal analyzer rotor with annular recessed optical window channel |
US4902479A (en) * | 1983-11-07 | 1990-02-20 | Fisher Scientific Company | Centrifugal analyzer rotor |
US4580897A (en) * | 1984-05-31 | 1986-04-08 | Allied Corporation | Centrifugal analyzer rotors |
US4580898A (en) * | 1984-05-31 | 1986-04-08 | Allied Corporation | Analytical system |
FR2572533B1 (en) * | 1984-10-26 | 1986-12-26 | Guigan Jean | METHOD FOR CARRYING OUT THE MEDICAL ANALYSIS OF A LIQUID SAMPLE USING AT LEAST ONE LIQUID REAGENT AND DEVICE FOR CARRYING OUT THE METHOD |
US5071625A (en) * | 1985-02-27 | 1991-12-10 | Fisher Scientific Company | Cuvette handling |
US5631166A (en) * | 1995-03-21 | 1997-05-20 | Jewell; Charles R. | Specimen disk for blood analyses |
US7722812B2 (en) * | 2003-12-08 | 2010-05-25 | Wako Pure Chemical Industries, Ltd. | Reaction disk and separation cell for automatic analyzer |
JP2005257337A (en) * | 2004-03-09 | 2005-09-22 | Brother Ind Ltd | Inspection object receiver, inspection device, and inspection method |
EP2189218A1 (en) * | 2008-11-12 | 2010-05-26 | F. Hoffmann-Roche AG | Multiwell plate lid separation |
-
0
- BE BE792516D patent/BE792516A/en unknown
-
1971
- 1971-12-09 US US00206379A patent/US3759666A/en not_active Expired - Lifetime
-
1972
- 1972-01-01 AR AR245535A patent/AR206681A1/en active
- 1972-11-22 CA CA157,152A patent/CA969384A/en not_active Expired
- 1972-12-07 IT IT70868/72A patent/IT988366B/en active
- 1972-12-08 AU AU49815/72A patent/AU465200B2/en not_active Expired
- 1972-12-08 NL NL7216731A patent/NL7216731A/xx not_active Application Discontinuation
- 1972-12-08 SE SE7216049A patent/SE406125B/en unknown
- 1972-12-08 BR BR008659/72A patent/BR7208659D0/en unknown
- 1972-12-08 FR FR7243849A patent/FR2164399A5/fr not_active Expired
- 1972-12-08 CH CH1793372A patent/CH553403A/en not_active IP Right Cessation
- 1972-12-08 JP JP47122609A patent/JPS5249758B2/ja not_active Expired
- 1972-12-08 IL IL41040A patent/IL41040A/en unknown
- 1972-12-08 GB GB5689172A patent/GB1392490A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
AU465200B2 (en) | 1975-09-18 |
DE2260280B2 (en) | 1976-09-23 |
FR2164399A5 (en) | 1973-07-27 |
IL41040A (en) | 1975-07-28 |
AR206681A1 (en) | 1976-08-13 |
JPS5249758B2 (en) | 1977-12-19 |
AU4981572A (en) | 1974-06-13 |
JPS4866491A (en) | 1973-09-12 |
BE792516A (en) | 1973-06-08 |
NL7216731A (en) | 1973-06-13 |
DE2260280A1 (en) | 1973-06-28 |
CH553403A (en) | 1974-08-30 |
SE406125B (en) | 1979-01-22 |
US3759666A (en) | 1973-09-18 |
CA969384A (en) | 1975-06-17 |
IL41040A0 (en) | 1973-02-28 |
IT988366B (en) | 1975-04-10 |
BR7208659D0 (en) | 1973-08-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
PCNP | Patent ceased through non-payment of renewal fee |