GB1391688A - Cyclic decapeptides - Google Patents
Cyclic decapeptidesInfo
- Publication number
- GB1391688A GB1391688A GB2836372A GB2836372A GB1391688A GB 1391688 A GB1391688 A GB 1391688A GB 2836372 A GB2836372 A GB 2836372A GB 2836372 A GB2836372 A GB 2836372A GB 1391688 A GB1391688 A GB 1391688A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pro
- phe
- och
- boc
- ala
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000004122 cyclic group Chemical group 0.000 title abstract 2
- CNBUSIJNWNXLQQ-NSHDSACASA-N (2s)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid Chemical compound CC(C)(C)OC(=O)N[C@H](C(O)=O)CC1=CC=C(O)C=C1 CNBUSIJNWNXLQQ-NSHDSACASA-N 0.000 abstract 4
- VUYWLCHFKCFCNH-QWRGUYRKSA-N (2s)-1-[(2s)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoyl]pyrrolidine-2-carboxylic acid Chemical compound CC(C)(C)OC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(O)=O VUYWLCHFKCFCNH-QWRGUYRKSA-N 0.000 abstract 3
- 108010073025 phenylalanylphenylalanine Proteins 0.000 abstract 3
- 108010015385 valyl-prolyl-proline Proteins 0.000 abstract 3
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical group OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 abstract 2
- KPKZJLCSROULON-QKGLWVMZSA-N Phalloidin Chemical compound N1C(=O)[C@@H]([C@@H](O)C)NC(=O)[C@H](C)NC(=O)[C@H](C[C@@](C)(O)CO)NC(=O)[C@H](C2)NC(=O)[C@H](C)NC(=O)[C@@H]3C[C@H](O)CN3C(=O)[C@@H]1CSC1=C2C2=CC=CC=C2N1 KPKZJLCSROULON-QKGLWVMZSA-N 0.000 abstract 2
- 108010011559 alanylphenylalanine Proteins 0.000 abstract 2
- VAMUDINSUBSTNS-AAEUAGOBSA-N (2s)-2-[[(2s)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-3-phenylpropanoic acid Chemical compound CC(C)(C)OC(=O)N[C@@H](C)C(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 VAMUDINSUBSTNS-AAEUAGOBSA-N 0.000 abstract 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
- 108010009711 Phalloidine Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 231100000636 lethal dose Toxicity 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
- 230000003381 solubilizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712130410 DE2130410A1 (de) | 1971-06-18 | 1971-06-18 | Neue cyclische dekapeptide und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1391688A true GB1391688A (en) | 1975-04-23 |
Family
ID=5811174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2836372A Expired GB1391688A (en) | 1971-06-18 | 1972-06-16 | Cyclic decapeptides |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3793304A (enExample) |
| CH (1) | CH591427A5 (enExample) |
| DE (1) | DE2130410A1 (enExample) |
| ES (1) | ES403938A1 (enExample) |
| FR (1) | FR2142082B1 (enExample) |
| GB (1) | GB1391688A (enExample) |
| NL (1) | NL7208241A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2921216A1 (de) * | 1979-05-25 | 1980-12-04 | Teschemacher Hansjoerg | Pharmakologisch aktive peptide |
-
1971
- 1971-06-18 DE DE19712130410 patent/DE2130410A1/de active Pending
-
1972
- 1972-06-09 US US00261256A patent/US3793304A/en not_active Expired - Lifetime
- 1972-06-15 CH CH896272A patent/CH591427A5/xx not_active IP Right Cessation
- 1972-06-16 NL NL7208241A patent/NL7208241A/xx not_active Application Discontinuation
- 1972-06-16 GB GB2836372A patent/GB1391688A/en not_active Expired
- 1972-06-16 ES ES403938A patent/ES403938A1/es not_active Expired
- 1972-06-19 FR FR7222042A patent/FR2142082B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES403938A1 (es) | 1975-05-16 |
| NL7208241A (enExample) | 1972-12-20 |
| US3793304A (en) | 1974-02-19 |
| DE2130410A1 (de) | 1973-01-25 |
| CH591427A5 (enExample) | 1977-09-15 |
| FR2142082A1 (enExample) | 1973-01-26 |
| FR2142082B1 (enExample) | 1975-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |