GB1387698A - 6alpha,9alpha-difluorosteroids of the pregnane series and processes for their manufacture - Google Patents
6alpha,9alpha-difluorosteroids of the pregnane series and processes for their manufactureInfo
- Publication number
- GB1387698A GB1387698A GB1893272A GB1893272A GB1387698A GB 1387698 A GB1387698 A GB 1387698A GB 1893272 A GB1893272 A GB 1893272A GB 1893272 A GB1893272 A GB 1893272A GB 1387698 A GB1387698 A GB 1387698A
- Authority
- GB
- United Kingdom
- Prior art keywords
- prepared
- steroids
- difluoro
- esterification
- april
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000003128 pregnanes Chemical class 0.000 title 1
- 230000032050 esterification Effects 0.000 abstract 2
- 238000005886 esterification reaction Methods 0.000 abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- -1 acryl Chemical group 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000006266 etherification reaction Methods 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000005907 ketalization reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003096 thymolvtic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH594471A CH563406A5 (enrdf_load_stackoverflow) | 1971-04-23 | 1971-04-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1387698A true GB1387698A (en) | 1975-03-19 |
Family
ID=4301904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1893272A Expired GB1387698A (en) | 1971-04-23 | 1972-04-24 | 6alpha,9alpha-difluorosteroids of the pregnane series and processes for their manufacture |
Country Status (9)
| Country | Link |
|---|---|
| AR (1) | AR193388A1 (enrdf_load_stackoverflow) |
| AU (1) | AU4145272A (enrdf_load_stackoverflow) |
| BE (1) | BE782521A (enrdf_load_stackoverflow) |
| CA (1) | CA969175A (enrdf_load_stackoverflow) |
| CH (1) | CH563406A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2218413A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2147911B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1387698A (enrdf_load_stackoverflow) |
| NL (1) | NL7205452A (enrdf_load_stackoverflow) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE35517E (en) * | 1987-08-25 | 1997-05-20 | University Of Southern California | Method, compositions, and compounds for modulating brain excitability |
| US5232917A (en) * | 1987-08-25 | 1993-08-03 | University Of Southern California | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series |
-
1971
- 1971-04-23 CH CH594471A patent/CH563406A5/xx not_active IP Right Cessation
-
1972
- 1972-04-15 DE DE19722218413 patent/DE2218413A1/de active Pending
- 1972-04-19 FR FR7213783A patent/FR2147911B1/fr not_active Expired
- 1972-04-19 CA CA139,988A patent/CA969175A/en not_active Expired
- 1972-04-20 AR AR24158672A patent/AR193388A1/es active
- 1972-04-21 BE BE782521A patent/BE782521A/xx unknown
- 1972-04-21 NL NL7205452A patent/NL7205452A/xx unknown
- 1972-04-21 AU AU41452/72A patent/AU4145272A/en not_active Expired
- 1972-04-24 GB GB1893272A patent/GB1387698A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU4145272A (en) | 1973-10-25 |
| DE2218413A1 (de) | 1972-11-09 |
| NL7205452A (enrdf_load_stackoverflow) | 1972-10-25 |
| CH563406A5 (enrdf_load_stackoverflow) | 1975-06-30 |
| BE782521A (fr) | 1972-10-23 |
| CA969175A (en) | 1975-06-10 |
| FR2147911A1 (enrdf_load_stackoverflow) | 1973-03-11 |
| AR193388A1 (es) | 1973-04-23 |
| FR2147911B1 (enrdf_load_stackoverflow) | 1975-08-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1494097A (en) | D-homo-20-keto-pregnanes | |
| GB1268230A (en) | Steroid glycosides and process for their manufacture | |
| GB1387698A (en) | 6alpha,9alpha-difluorosteroids of the pregnane series and processes for their manufacture | |
| GB1363472A (en) | 17-chlorosteroids | |
| GB1211220A (en) | 21-aldehydes of the pregnane series and derivatives thereof and process for their manufacture | |
| ES457968A1 (es) | Procedimiento para la preparacion de corticoides. | |
| GB1440064A (en) | Delta8-9- steroids of the pregnane series | |
| GB1384994A (en) | Pregnane-21-aldehydes and their derivatives and a process for the production thereof | |
| GB1409240A (en) | Anaesthetic steroid of the 5alpha-pregnane series | |
| GB1296159A (enrdf_load_stackoverflow) | ||
| GB1213118A (en) | PROCESS FOR PREPARING 9alpha-FLUORO-16-METHYLENE-PREDNISOLONE OR PREDNISONE, AND 21-ESTERS THEREOF | |
| GB1276743A (en) | Aldehydes of the pregnane series and process for their manufacture | |
| GB1343975A (en) | 16beta-difluoromethyl and 16-fifluoromethylene steroids and processes for their preparation | |
| GB1311725A (en) | 18-cyano pregnane compounds and process for their manufacture | |
| GB1505461A (en) | Steriod 21-o-esters with a substituted acetic acid their preparation and use | |
| GB1235642A (en) | A new oestratriol and a process for its manufacture | |
| GB1464509A (en) | Esters of steroid 21-ols | |
| ES358829A1 (es) | Procedimiento para la preparacion de esteroides c17-oxige- nados de la serie androstanica. | |
| IE35059L (en) | New halogeno-steroids. | |
| GB1250394A (enrdf_load_stackoverflow) | ||
| GB1196476A (en) | 21-Fluoro-Delta<4,6>-Pregnadienes and process for their manufacture | |
| GB1377975A (en) | 17alpha-hydroxy-16alpha,18-dimethyl-delta4-pregnene-3,20-dione and its esters | |
| GB1215164A (en) | 21-sulphonated pregnadienes | |
| GB1527249A (en) | 6-fluoro-16-methyl-pregna-1,4,8-triene-3,20-diones | |
| GB1289852A (enrdf_load_stackoverflow) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |