GB1384843A - Benzofuran derivatives their preparation and compositions containing them - Google Patents
Benzofuran derivatives their preparation and compositions containing themInfo
- Publication number
- GB1384843A GB1384843A GB2085673A GB2085673A GB1384843A GB 1384843 A GB1384843 A GB 1384843A GB 2085673 A GB2085673 A GB 2085673A GB 2085673 A GB2085673 A GB 2085673A GB 1384843 A GB1384843 A GB 1384843A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- resulting
- alkyl
- chloro
- aminoethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 150000001907 coumarones Chemical class 0.000 title 1
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 abstract 4
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 abstract 4
- 150000008062 acetophenones Chemical class 0.000 abstract 3
- 239000012458 free base Substances 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- VZTDIZULWFCMLS-UHFFFAOYSA-N ammonium formate Chemical compound [NH4+].[O-]C=O VZTDIZULWFCMLS-UHFFFAOYSA-N 0.000 abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 2
- 150000003840 hydrochlorides Chemical class 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 229910001629 magnesium chloride Inorganic materials 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7216448A FR2183536B1 (enrdf_load_stackoverflow) | 1972-05-09 | 1972-05-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1384843A true GB1384843A (en) | 1975-02-26 |
Family
ID=9098191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2085673A Expired GB1384843A (en) | 1972-05-09 | 1973-05-02 | Benzofuran derivatives their preparation and compositions containing them |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE798795A (enrdf_load_stackoverflow) |
| CH (1) | CH575406A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2323005A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2183536B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1384843A (enrdf_load_stackoverflow) |
| NL (1) | NL7306430A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4254140A (en) | 1980-03-20 | 1981-03-03 | Smithkline Corporation | 4-(2-Aminoethyl)-7-hydroxy-2-methyl-2,3-dihydrobenzofurans |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1476906A (en) * | 1975-02-19 | 1977-06-16 | Beecham Group Ltd | Aromatic ethers and thioethers |
| DE3110009A1 (de) * | 1981-03-11 | 1982-09-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue benzofuran-derivate, ihre herstellung und verwendung |
| US5149838A (en) * | 1991-09-20 | 1992-09-22 | Merck & Co., Inc. | Intermediates for substituted azetidinones useful as anti-inflammatory and antidegenerative agents |
| FR2752839B1 (fr) * | 1996-08-29 | 1998-10-09 | Synthelabo | Derives de benzofurane, leur preparation et leur application en therapeutique |
-
1972
- 1972-05-09 FR FR7216448A patent/FR2183536B1/fr not_active Expired
-
1973
- 1973-04-27 BE BE2052739A patent/BE798795A/xx unknown
- 1973-05-02 GB GB2085673A patent/GB1384843A/en not_active Expired
- 1973-05-07 CH CH641473A patent/CH575406A5/xx not_active IP Right Cessation
- 1973-05-08 DE DE19732323005 patent/DE2323005A1/de active Pending
- 1973-05-08 NL NL7306430A patent/NL7306430A/xx not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4254140A (en) | 1980-03-20 | 1981-03-03 | Smithkline Corporation | 4-(2-Aminoethyl)-7-hydroxy-2-methyl-2,3-dihydrobenzofurans |
Also Published As
| Publication number | Publication date |
|---|---|
| BE798795A (fr) | 1973-08-16 |
| CH575406A5 (enrdf_load_stackoverflow) | 1976-05-14 |
| DE2323005A1 (de) | 1974-01-17 |
| FR2183536A1 (enrdf_load_stackoverflow) | 1973-12-21 |
| FR2183536B1 (enrdf_load_stackoverflow) | 1975-06-20 |
| NL7306430A (enrdf_load_stackoverflow) | 1973-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |