GB1380875A - Lithium salts of amino-acids - Google Patents
Lithium salts of amino-acidsInfo
- Publication number
- GB1380875A GB1380875A GB3586573A GB3586573A GB1380875A GB 1380875 A GB1380875 A GB 1380875A GB 3586573 A GB3586573 A GB 3586573A GB 3586573 A GB3586573 A GB 3586573A GB 1380875 A GB1380875 A GB 1380875A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acetyl
- lithium
- acids
- amino
- lithium salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910003002 lithium salt Inorganic materials 0.000 title abstract 2
- 159000000002 lithium salts Chemical class 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 title 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 2
- 229910052744 lithium Inorganic materials 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 abstract 1
- 125000003047 N-acetyl group Chemical group 0.000 abstract 1
- OTCCIMWXFLJLIA-BYPYZUCNSA-N N-acetyl-L-aspartic acid Chemical compound CC(=O)N[C@H](C(O)=O)CC(O)=O OTCCIMWXFLJLIA-BYPYZUCNSA-N 0.000 abstract 1
- RFMMMVDNIPUKGG-YFKPBYRVSA-N N-acetyl-L-glutamic acid Chemical compound CC(=O)N[C@H](C(O)=O)CCC(O)=O RFMMMVDNIPUKGG-YFKPBYRVSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229940024606 amino acid Drugs 0.000 abstract 1
- 208000028683 bipolar I disease Diseases 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- WMFOQBRAJBCJND-UHFFFAOYSA-M lithium hydroxide Inorganic materials [Li+].[OH-] WMFOQBRAJBCJND-UHFFFAOYSA-M 0.000 abstract 1
- FUJCRWPEOMXPAD-UHFFFAOYSA-N lithium oxide Chemical compound [Li+].[Li+].[O-2] FUJCRWPEOMXPAD-UHFFFAOYSA-N 0.000 abstract 1
- 229910001947 lithium oxide Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
1380875 Lithium salts of N-acetyl-aminoacids SOC D'ETUDES ET D'EXPLOITATION DE MARQUES ET BREVETS 27 July 1973 [28 July 1972] 35865/73 Heading C2C The novel salts lithium N-acetyl-L-glutamate and lithium N-acetyl-L-aspartate are prepared by reacting the N-acetyl acid with lithium oxide, hydroxide or carbamate. Pharmaceutical compositions in conventional forms for oral administration and used in manicdepressive syndromes comprise an above salt and an excipient.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7227292A FR2193585B1 (en) | 1972-07-28 | 1972-07-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1380875A true GB1380875A (en) | 1975-01-15 |
Family
ID=9102523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3586573A Expired GB1380875A (en) | 1972-07-28 | 1973-07-27 | Lithium salts of amino-acids |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS49100213A (en) |
| AT (1) | AT321875B (en) |
| BE (1) | BE802429A (en) |
| CA (1) | CA994802A (en) |
| CH (1) | CH571476A5 (en) |
| DE (1) | DE2337974A1 (en) |
| ES (1) | ES417328A1 (en) |
| FR (1) | FR2193585B1 (en) |
| GB (1) | GB1380875A (en) |
| NL (1) | NL7310306A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108348500A (en) * | 2015-10-23 | 2018-07-31 | 诺姆制药有限责任公司 | Drug with resisting stress, antianxiety and antidepressant activity and its on the basis of composition |
| RU2677879C1 (en) * | 2017-10-11 | 2019-01-22 | федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет" (ФГБОУ ВО "ВГУ") | Lithio-beta-phenyl-gamma-aminobutyrate as mood stabilizing agent |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3837182C2 (en) * | 1987-11-05 | 2000-01-13 | Zahnradfabrik Friedrichshafen | Flow dividing valve |
| EP1319663A1 (en) * | 2001-12-17 | 2003-06-18 | Dospharma S.A. | Antidepressant folic -, folinic- and glutamic-acid lithium salts |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE660106A (en) * | 1964-03-26 | 1965-06-16 |
-
1972
- 1972-07-28 FR FR7227292A patent/FR2193585B1/fr not_active Expired
-
1973
- 1973-07-17 BE BE2052923A patent/BE802429A/en unknown
- 1973-07-24 CA CA177,275A patent/CA994802A/en not_active Expired
- 1973-07-24 NL NL7310306A patent/NL7310306A/xx unknown
- 1973-07-25 AT AT654173A patent/AT321875B/en not_active IP Right Cessation
- 1973-07-26 CH CH1091073A patent/CH571476A5/xx not_active IP Right Cessation
- 1973-07-26 DE DE19732337974 patent/DE2337974A1/en active Pending
- 1973-07-27 ES ES417328A patent/ES417328A1/en not_active Expired
- 1973-07-27 GB GB3586573A patent/GB1380875A/en not_active Expired
- 1973-07-28 JP JP48084621A patent/JPS49100213A/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108348500A (en) * | 2015-10-23 | 2018-07-31 | 诺姆制药有限责任公司 | Drug with resisting stress, antianxiety and antidepressant activity and its on the basis of composition |
| RU2677879C1 (en) * | 2017-10-11 | 2019-01-22 | федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет" (ФГБОУ ВО "ВГУ") | Lithio-beta-phenyl-gamma-aminobutyrate as mood stabilizing agent |
Also Published As
| Publication number | Publication date |
|---|---|
| BE802429A (en) | 1973-11-16 |
| FR2193585A1 (en) | 1974-02-22 |
| ES417328A1 (en) | 1976-06-16 |
| DE2337974A1 (en) | 1974-02-07 |
| JPS49100213A (en) | 1974-09-21 |
| NL7310306A (en) | 1974-01-30 |
| FR2193585B1 (en) | 1975-08-08 |
| AT321875B (en) | 1975-04-25 |
| CH571476A5 (en) | 1976-01-15 |
| CA994802A (en) | 1976-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |