GB1376277A - Sustained release medicaments - Google Patents

Sustained release medicaments

Info

Publication number
GB1376277A
GB1376277A GB2208373A GB2208373A GB1376277A GB 1376277 A GB1376277 A GB 1376277A GB 2208373 A GB2208373 A GB 2208373A GB 2208373 A GB2208373 A GB 2208373A GB 1376277 A GB1376277 A GB 1376277A
Authority
GB
United Kingdom
Prior art keywords
oxide
sustained release
solid
release medicaments
pores
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2208373A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Battelle Institut eV
Original Assignee
Battelle Institut eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Institut eV filed Critical Battelle Institut eV
Priority to GB2208373A priority Critical patent/GB1376277A/en
Publication of GB1376277A publication Critical patent/GB1376277A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

1376277 Sustained release medicaments BATTELLE-INSTITUT eV 9 May 1973 22083/ 73 Heading A5B Sustained release medicaments comprise a medicament present (either as such or as a solution) in the "inkwell pores" of a porous solid which is substantially insoluble in body fluids. The said pores comprise cavities in the solid connected to the surface by a narrower "neck" which has a mean diameter less than half that of the cavity and is below 0.1Ám. The solid may be a "ceramic" oxide, e.g. aluminium, zirconium or silicon oxide, a metal or a synthetic polymer. Various methods of preparing materials having the requisite properties are given including compression moulding and optionally, sintering, dehydrating oxide or hydroxide gels and hydrolysing alcoholates in organic solvents. The active material may be mixed with the starting materials in such processes or the product may be impregnated with the molten material or with solutions thereof, the solvent of which may subsequently be removed. Examples relate to products comprising a) benzoic acid in silica gel and b) 1- propyl-1-cyclohexyl - 2 - methylaminopropane HCI in Aluminium oxide.
GB2208373A 1973-05-09 1973-05-09 Sustained release medicaments Expired GB1376277A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2208373A GB1376277A (en) 1973-05-09 1973-05-09 Sustained release medicaments

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2208373A GB1376277A (en) 1973-05-09 1973-05-09 Sustained release medicaments

Publications (1)

Publication Number Publication Date
GB1376277A true GB1376277A (en) 1974-12-04

Family

ID=10173654

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2208373A Expired GB1376277A (en) 1973-05-09 1973-05-09 Sustained release medicaments

Country Status (1)

Country Link
GB (1) GB1376277A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0213918A2 (en) * 1985-08-23 1987-03-11 Sumitomo Electric Industries Limited A process for producing a medical resin composition.
US7354602B2 (en) 2000-02-21 2008-04-08 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
US8790697B2 (en) 2004-09-09 2014-07-29 K.U. Leuven Research & Development Controlled release delivery system for bio-active agents

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0213918A2 (en) * 1985-08-23 1987-03-11 Sumitomo Electric Industries Limited A process for producing a medical resin composition.
EP0213918A3 (en) * 1985-08-23 1988-02-03 Sumitomo Electric Industries Limited Medical resin composition and process for producing the same
US7354602B2 (en) 2000-02-21 2008-04-08 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
US7354603B2 (en) 2000-02-21 2008-04-08 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
US7357948B2 (en) 2000-02-21 2008-04-15 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
US7585521B2 (en) 2000-02-21 2009-09-08 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
US8790697B2 (en) 2004-09-09 2014-07-29 K.U. Leuven Research & Development Controlled release delivery system for bio-active agents

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee