GB1375836A - - Google Patents
Info
- Publication number
- GB1375836A GB1375836A GB495071A GB495071A GB1375836A GB 1375836 A GB1375836 A GB 1375836A GB 495071 A GB495071 A GB 495071A GB 495071 A GB495071 A GB 495071A GB 1375836 A GB1375836 A GB 1375836A
- Authority
- GB
- United Kingdom
- Prior art keywords
- piperidine
- alkyl
- benzyl
- ring
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 4
- FTAHXMZRJCZXDL-UHFFFAOYSA-N 3-piperideine Chemical compound C1CC=CCN1 FTAHXMZRJCZXDL-UHFFFAOYSA-N 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 229940054051 antipsychotic indole derivative Drugs 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 150000002475 indoles Chemical class 0.000 abstract 2
- 125000003386 piperidinyl group Chemical group 0.000 abstract 2
- 125000006705 (C5-C7) cycloalkyl group Chemical group 0.000 abstract 1
- YUBDLZGUSSWQSS-UHFFFAOYSA-N 1-benzylpiperidin-4-amine Chemical compound C1CC(N)CCN1CC1=CC=CC=C1 YUBDLZGUSSWQSS-UHFFFAOYSA-N 0.000 abstract 1
- RVNIFQHYLAWJDT-UHFFFAOYSA-N 3-methoxy-n-piperidin-4-ylbenzamide Chemical compound COC1=CC=CC(C(=O)NC2CCNCC2)=C1 RVNIFQHYLAWJDT-UHFFFAOYSA-N 0.000 abstract 1
- YOEGOTABDHBSJE-UHFFFAOYSA-N 4-methyl-n-piperidin-4-ylbenzamide Chemical compound C1=CC(C)=CC=C1C(=O)NC1CCNCC1 YOEGOTABDHBSJE-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003435 aroyl group Chemical group 0.000 abstract 1
- 125000002102 aryl alkyloxo group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- RVOJTCZRIKWHDX-UHFFFAOYSA-N cyclohexanecarbonyl chloride Chemical compound ClC(=O)C1CCCCC1 RVOJTCZRIKWHDX-UHFFFAOYSA-N 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- WUDUFRBXYAYWEV-UHFFFAOYSA-N n-(1-benzylpiperidin-4-yl)-4-methylbenzamide Chemical compound C1=CC(C)=CC=C1C(=O)NC1CCN(CC=2C=CC=CC=2)CC1 WUDUFRBXYAYWEV-UHFFFAOYSA-N 0.000 abstract 1
- LDGORKJXEGHFBK-UHFFFAOYSA-N n-(1-benzylpiperidin-4-yl)benzamide Chemical compound C=1C=CC=CC=1C(=O)NC(CC1)CCN1CC1=CC=CC=C1 LDGORKJXEGHFBK-UHFFFAOYSA-N 0.000 abstract 1
- KPKHZUZWCXNNOG-UHFFFAOYSA-N n-(1-benzylpiperidin-4-yl)cyclohexanecarboxamide Chemical compound C1CCCCC1C(=O)NC(CC1)CCN1CC1=CC=CC=C1 KPKHZUZWCXNNOG-UHFFFAOYSA-N 0.000 abstract 1
- AUJTUJNVNBZXGF-UHFFFAOYSA-N n-piperidin-4-ylcyclohexanecarboxamide Chemical compound C1CCCCC1C(=O)NC1CCNCC1 AUJTUJNVNBZXGF-UHFFFAOYSA-N 0.000 abstract 1
- 150000003053 piperidines Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB495071A GB1375836A (cg-RX-API-DMAC7.html) | 1971-02-18 | 1971-02-18 | |
| CA134,251A CA973882A (en) | 1971-02-18 | 1972-02-08 | Indoles |
| NL7201854A NL7201854A (cg-RX-API-DMAC7.html) | 1971-02-18 | 1972-02-11 | |
| DK66772A DK134553B (da) | 1971-02-18 | 1972-02-14 | Fremgangsmåde til fremstilling af indolderivater eller syreadditionssalte eller kvaternære ammoniumsalte deraf. |
| FR7205015A FR2135126B2 (cg-RX-API-DMAC7.html) | 1971-02-18 | 1972-02-15 | |
| DE19722207258 DE2207258A1 (de) | 1971-02-18 | 1972-02-16 | Verfahren zur Herstellung von Indolderivaten für solche Verbindungen enthaltend pharmazeutische Zubereitungen |
| JP1688972A JPS5545553B1 (cg-RX-API-DMAC7.html) | 1971-02-18 | 1972-02-17 | |
| SE192972A SE383746B (sv) | 1971-02-18 | 1972-02-17 | Nytt forfarande att framstella terapeutiskt verdefulla indolderivat |
| CH232372A CH570996A5 (cg-RX-API-DMAC7.html) | 1971-02-18 | 1972-02-18 | |
| BE779578A BE779578R (fr) | 1971-02-18 | 1972-02-18 | Derives de l'indole et leur |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB495071A GB1375836A (cg-RX-API-DMAC7.html) | 1971-02-18 | 1971-02-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1375836A true GB1375836A (cg-RX-API-DMAC7.html) | 1974-11-27 |
Family
ID=9786946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB495071A Expired GB1375836A (cg-RX-API-DMAC7.html) | 1971-02-18 | 1971-02-18 |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS5545553B1 (cg-RX-API-DMAC7.html) |
| BE (1) | BE779578R (cg-RX-API-DMAC7.html) |
| CA (1) | CA973882A (cg-RX-API-DMAC7.html) |
| CH (1) | CH570996A5 (cg-RX-API-DMAC7.html) |
| DE (1) | DE2207258A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK134553B (cg-RX-API-DMAC7.html) |
| FR (1) | FR2135126B2 (cg-RX-API-DMAC7.html) |
| GB (1) | GB1375836A (cg-RX-API-DMAC7.html) |
| NL (1) | NL7201854A (cg-RX-API-DMAC7.html) |
| SE (1) | SE383746B (cg-RX-API-DMAC7.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004002490A3 (en) * | 2002-06-26 | 2005-10-27 | Glaxo Group Ltd | Piperidine compounds as antibacterials |
-
1971
- 1971-02-18 GB GB495071A patent/GB1375836A/en not_active Expired
-
1972
- 1972-02-08 CA CA134,251A patent/CA973882A/en not_active Expired
- 1972-02-11 NL NL7201854A patent/NL7201854A/xx unknown
- 1972-02-14 DK DK66772A patent/DK134553B/da not_active IP Right Cessation
- 1972-02-15 FR FR7205015A patent/FR2135126B2/fr not_active Expired
- 1972-02-16 DE DE19722207258 patent/DE2207258A1/de not_active Withdrawn
- 1972-02-17 JP JP1688972A patent/JPS5545553B1/ja active Pending
- 1972-02-17 SE SE192972A patent/SE383746B/xx unknown
- 1972-02-18 BE BE779578A patent/BE779578R/xx not_active IP Right Cessation
- 1972-02-18 CH CH232372A patent/CH570996A5/xx not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004002490A3 (en) * | 2002-06-26 | 2005-10-27 | Glaxo Group Ltd | Piperidine compounds as antibacterials |
| US7498326B2 (en) | 2002-06-26 | 2009-03-03 | Glaxo Group Limited | Compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| BE779578R (fr) | 1972-08-18 |
| SE383746B (sv) | 1976-03-29 |
| NL7201854A (cg-RX-API-DMAC7.html) | 1972-08-22 |
| DK134553C (cg-RX-API-DMAC7.html) | 1977-05-02 |
| CH570996A5 (cg-RX-API-DMAC7.html) | 1975-12-31 |
| FR2135126B2 (cg-RX-API-DMAC7.html) | 1975-10-24 |
| CA973882A (en) | 1975-09-02 |
| DK134553B (da) | 1976-11-29 |
| DE2207258A1 (de) | 1972-09-07 |
| FR2135126A2 (cg-RX-API-DMAC7.html) | 1972-12-15 |
| JPS5545553B1 (cg-RX-API-DMAC7.html) | 1980-11-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |