GB1374979A - 3,5-dioxopiperazine derivatives - Google Patents

3,5-dioxopiperazine derivatives

Info

Publication number
GB1374979A
GB1374979A GB6056470A GB6056470A GB1374979A GB 1374979 A GB1374979 A GB 1374979A GB 6056470 A GB6056470 A GB 6056470A GB 6056470 A GB6056470 A GB 6056470A GB 1374979 A GB1374979 A GB 1374979A
Authority
GB
United Kingdom
Prior art keywords
carbons
alkynyl
march
alkenyl
chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB6056470A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NAT RES DEV
National Research Development Corp UK
Original Assignee
NAT RES DEV
National Research Development Corp UK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NAT RES DEV, National Research Development Corp UK filed Critical NAT RES DEV
Priority to GB6056470A priority Critical patent/GB1374979A/en
Priority to ZA718200A priority patent/ZA718200B/xx
Priority to IL3834271A priority patent/IL38342A/xx
Priority to AU36837/71A priority patent/AU470566B2/en
Priority to CH246974A priority patent/CH563997A5/xx
Priority to FR7145674A priority patent/FR2154389B2/fr
Priority to CH1855871A priority patent/CH564541A5/xx
Priority to BE776958A priority patent/BE776958R/xx
Priority to CA130,520A priority patent/CA1002049A/en
Priority to SE1635671A priority patent/SE400286B/xx
Priority to DE19712163601 priority patent/DE2163601A1/de
Priority to NL7117573A priority patent/NL7117573A/xx
Priority to CH246874A priority patent/CH563996A5/xx
Publication of GB1374979A publication Critical patent/GB1374979A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB6056470A 1968-07-02 1970-12-21 3,5-dioxopiperazine derivatives Expired GB1374979A (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
GB6056470A GB1374979A (en) 1970-12-21 1970-12-21 3,5-dioxopiperazine derivatives
ZA718200A ZA718200B (en) 1970-12-21 1971-12-07 Pharmaceutical compositions
IL3834271A IL38342A (en) 1970-12-21 1971-12-13 Bis(3,5-dixopiperazin-1-yl)alkane compounds and pharmaceutical compositions containing them
AU36837/71A AU470566B2 (en) 1970-12-21 1971-12-14 3, 5-dioxopiperazine derivatives
CH246974A CH563997A5 (enrdf_load_stackoverflow) 1970-12-21 1971-12-20
FR7145674A FR2154389B2 (enrdf_load_stackoverflow) 1970-12-21 1971-12-20
CH1855871A CH564541A5 (enrdf_load_stackoverflow) 1970-12-21 1971-12-20
BE776958A BE776958R (fr) 1970-12-21 1971-12-20 Tetra-oxo-1,2-dipiperazino-alcanes et procede pour leur
CA130,520A CA1002049A (en) 1970-12-21 1971-12-20 3,5-dioxopiperazinyl derivatives
SE1635671A SE400286B (sv) 1970-12-21 1971-12-20 Sett att framstella bis-3,5-dioxopiperaziner
DE19712163601 DE2163601A1 (de) 1970-12-21 1971-12-21 Arzneimittel mit einem Gehalt an (3,5,3,5-Tetraoxo)-1,2-dipiperazinoalkanverbindungen und Verfahren zur Herstellung der Verbindungen
NL7117573A NL7117573A (nl) 1968-07-02 1971-12-21 Verbindingen met anti-kankerwerking
CH246874A CH563996A5 (enrdf_load_stackoverflow) 1970-12-21 1974-01-18

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB6056470A GB1374979A (en) 1970-12-21 1970-12-21 3,5-dioxopiperazine derivatives
GB710071 1971-03-17

Publications (1)

Publication Number Publication Date
GB1374979A true GB1374979A (en) 1974-11-20

Family

ID=26241204

Family Applications (1)

Application Number Title Priority Date Filing Date
GB6056470A Expired GB1374979A (en) 1968-07-02 1970-12-21 3,5-dioxopiperazine derivatives

Country Status (9)

Country Link
AU (1) AU470566B2 (enrdf_load_stackoverflow)
BE (1) BE776958R (enrdf_load_stackoverflow)
CA (1) CA1002049A (enrdf_load_stackoverflow)
CH (3) CH563997A5 (enrdf_load_stackoverflow)
DE (1) DE2163601A1 (enrdf_load_stackoverflow)
FR (1) FR2154389B2 (enrdf_load_stackoverflow)
GB (1) GB1374979A (enrdf_load_stackoverflow)
IL (1) IL38342A (enrdf_load_stackoverflow)
SE (1) SE400286B (enrdf_load_stackoverflow)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755619A (en) * 1985-04-01 1988-07-05 National Research Development Corporation Pharmaceutical compositions
GB2229362A (en) * 1989-01-31 1990-09-26 Kurt Hellmann Radiosensitising compositions comprising a razoxane optical isomer
US5149710A (en) * 1985-04-01 1992-09-22 National Research Development Corporation Pharmaceutical compositions for treating psoriasis
US5162372A (en) * 1985-04-01 1992-11-10 National Research Development Corporation Pharmaceutical compositions for treating certain cancers
WO1993010104A1 (en) * 1991-11-18 1993-05-27 Windleshaw Enterprises Ltd Bis(3,5-dioxoalkylpiperazine) derivatives for use in preventing or treating conditions that involve iron metabolism
US5278187A (en) * 1985-04-01 1994-01-11 British Technology Group Ltd. Pharmaceutical compositions
US5316756A (en) * 1983-07-01 1994-05-31 Schering Aktiengesellschaft NMR imaging using paramagnetic chelates having hydroxyalkyl-substituted amide groups
US5399340A (en) * 1987-09-24 1995-03-21 Schering Aktiengesellschaft Use of amide complex compounds
US5438057A (en) * 1991-07-12 1995-08-01 British Technology Group Limited Pharmaceutical compositions
US5482700A (en) * 1987-03-31 1996-01-09 Schering Aktiengesellschaft Substituted polyamino, polycarboxy complexing agent dimers for MRI and X-ray contrast
US5693309A (en) * 1987-03-31 1997-12-02 Schering Aktiengesellschaft Substituted complexing agents, complexes, and complex salts, processes for their production, and pharmaceuticals containing same
US5695739A (en) * 1989-06-30 1997-12-09 Schering Aktiengesellschaft Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
US5746995A (en) * 1994-11-30 1998-05-05 Schering Aktiengesellschaft DTPA derivatives substituted in a novel way, their metal complexes, and their use in diagnosis and therapy
US6039931A (en) * 1989-06-30 2000-03-21 Schering Aktiengesellschaft Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3710730A1 (de) * 1987-03-31 1988-10-20 Schering Ag Substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel
US4963679A (en) * 1988-02-17 1990-10-16 Erbamont, Inc. Process for preparing bis (3,5-dioxopiperazinyl) alkanes or alkenes
GB8916072D0 (en) * 1989-07-13 1989-08-31 Creighton Andrew M Pharmaceutical compositions
US6265385B1 (en) * 1996-01-11 2001-07-24 Topo Target Aps Topoisomerase II poison and bis-dioxopiperazine derivative combination therapy

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5316756A (en) * 1983-07-01 1994-05-31 Schering Aktiengesellschaft NMR imaging using paramagnetic chelates having hydroxyalkyl-substituted amide groups
US5419894A (en) * 1983-07-01 1995-05-30 Schering Aktiengesellschaft Complexing agents, complexes and complex salts
US4902714A (en) * 1985-04-01 1990-02-20 National Research Development Corporation Pharmaceutical compositions
US4755619A (en) * 1985-04-01 1988-07-05 National Research Development Corporation Pharmaceutical compositions
US5149710A (en) * 1985-04-01 1992-09-22 National Research Development Corporation Pharmaceutical compositions for treating psoriasis
US5162372A (en) * 1985-04-01 1992-11-10 National Research Development Corporation Pharmaceutical compositions for treating certain cancers
US5278187A (en) * 1985-04-01 1994-01-11 British Technology Group Ltd. Pharmaceutical compositions
US5693309A (en) * 1987-03-31 1997-12-02 Schering Aktiengesellschaft Substituted complexing agents, complexes, and complex salts, processes for their production, and pharmaceuticals containing same
US5482700A (en) * 1987-03-31 1996-01-09 Schering Aktiengesellschaft Substituted polyamino, polycarboxy complexing agent dimers for MRI and X-ray contrast
US5399340A (en) * 1987-09-24 1995-03-21 Schering Aktiengesellschaft Use of amide complex compounds
GB2229362A (en) * 1989-01-31 1990-09-26 Kurt Hellmann Radiosensitising compositions comprising a razoxane optical isomer
US5695739A (en) * 1989-06-30 1997-12-09 Schering Aktiengesellschaft Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
US5798092A (en) * 1989-06-30 1998-08-25 Schering Aktiengesellschaft Derivatized DTPA complexes pharmaceutical agents containing these compounds, their use, and processes for their production
US6039931A (en) * 1989-06-30 2000-03-21 Schering Aktiengesellschaft Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
US5438057A (en) * 1991-07-12 1995-08-01 British Technology Group Limited Pharmaceutical compositions
WO1993010104A1 (en) * 1991-11-18 1993-05-27 Windleshaw Enterprises Ltd Bis(3,5-dioxoalkylpiperazine) derivatives for use in preventing or treating conditions that involve iron metabolism
US5746995A (en) * 1994-11-30 1998-05-05 Schering Aktiengesellschaft DTPA derivatives substituted in a novel way, their metal complexes, and their use in diagnosis and therapy
US5853699A (en) * 1994-11-30 1998-12-29 Schering Aktiengesellschaft Use of tetra azacycle complexes as x-ray diagnostic agents for the liver and gallbladder

Also Published As

Publication number Publication date
BE776958R (fr) 1972-06-20
CH563997A5 (enrdf_load_stackoverflow) 1975-07-15
DE2163601A1 (de) 1972-06-22
SE400286B (sv) 1978-03-20
CH563996A5 (enrdf_load_stackoverflow) 1975-07-15
FR2154389B2 (enrdf_load_stackoverflow) 1975-11-28
CH564541A5 (enrdf_load_stackoverflow) 1975-07-31
IL38342A (en) 1978-03-10
FR2154389A2 (enrdf_load_stackoverflow) 1973-05-11
CA1002049A (en) 1976-12-21
AU470566B2 (en) 1976-03-18
AU3683771A (en) 1973-06-21

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Legal Events

Date Code Title Description
PS Patent sealed
PE20 Patent expired after termination of 20 years