GB1374556A - Phenylalanine derivatives - Google Patents
Phenylalanine derivativesInfo
- Publication number
- GB1374556A GB1374556A GB2298873A GB2298873A GB1374556A GB 1374556 A GB1374556 A GB 1374556A GB 2298873 A GB2298873 A GB 2298873A GB 2298873 A GB2298873 A GB 2298873A GB 1374556 A GB1374556 A GB 1374556A
- Authority
- GB
- United Kingdom
- Prior art keywords
- prepared
- compound
- formula
- dimethyl
- give
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002993 phenylalanine derivatives Chemical class 0.000 title abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical compound BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- SSBIODGYQFXYTK-UHFFFAOYSA-N 5-methoxy-2,4-dimethylbenzaldehyde Chemical compound COC1=CC(C=O)=C(C)C=C1C SSBIODGYQFXYTK-UHFFFAOYSA-N 0.000 abstract 1
- VFFWKQUWLDFKBJ-UHFFFAOYSA-N 5-methoxy-2,4-dimethylbenzoic acid Chemical compound CC1=C(C(=O)O)C=C(C(=C1)C)OC VFFWKQUWLDFKBJ-UHFFFAOYSA-N 0.000 abstract 1
- ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 abstract 1
- LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical class C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 abstract 1
- 238000006280 Rosenmund reaction Methods 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal cyanide Chemical class 0.000 abstract 1
- 239000001099 ammonium carbonate Substances 0.000 abstract 1
- 235000012501 ammonium carbonate Nutrition 0.000 abstract 1
- 150000003935 benzaldehydes Chemical class 0.000 abstract 1
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzenecarboxaldehyde Natural products O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 abstract 1
- PASDCCFISLVPSO-UHFFFAOYSA-N benzoyl chloride Chemical compound ClC(=O)C1=CC=CC=C1 PASDCCFISLVPSO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 abstract 1
- 229940091173 hydantoin Drugs 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000011987 methylation Effects 0.000 abstract 1
- 238000007069 methylation reaction Methods 0.000 abstract 1
- 150000002828 nitro derivatives Chemical class 0.000 abstract 1
- 125000004971 nitroalkyl group Chemical group 0.000 abstract 1
- QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000007965 phenolic acids Chemical class 0.000 abstract 1
- 150000002989 phenols Chemical class 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2455672 | 1972-05-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1374556A true GB1374556A (en) | 1974-11-20 |
Family
ID=11213957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2298873A Expired GB1374556A (en) | 1972-05-19 | 1973-05-15 | Phenylalanine derivatives |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS4966650A (cg-RX-API-DMAC10.html) |
| DE (1) | DE2324535A1 (cg-RX-API-DMAC10.html) |
| FR (1) | FR2185404B1 (cg-RX-API-DMAC10.html) |
| GB (1) | GB1374556A (cg-RX-API-DMAC10.html) |
| HU (1) | HU166777B (cg-RX-API-DMAC10.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61167650A (ja) * | 1985-01-21 | 1986-07-29 | Showa Denko Kk | Ｄｌ−フエニルアラニンの製造方法 |
-
1973
- 1973-05-15 DE DE19732324535 patent/DE2324535A1/de active Pending
- 1973-05-15 GB GB2298873A patent/GB1374556A/en not_active Expired
- 1973-05-16 FR FR7317632A patent/FR2185404B1/fr not_active Expired
- 1973-05-17 JP JP5415073A patent/JPS4966650A/ja active Pending
- 1973-05-17 HU HUSO001076 patent/HU166777B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2185404A1 (cg-RX-API-DMAC10.html) | 1974-01-04 |
| HU166777B (cg-RX-API-DMAC10.html) | 1975-05-28 |
| DE2324535A1 (de) | 1973-11-29 |
| JPS4966650A (cg-RX-API-DMAC10.html) | 1974-06-27 |
| FR2185404B1 (cg-RX-API-DMAC10.html) | 1978-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |