GB1366319A - Sa 8-amino-theohylline derivatives process for their preparation and therapeutic compositon containing same - Google Patents
Sa 8-amino-theohylline derivatives process for their preparation and therapeutic compositon containing sameInfo
- Publication number
- GB1366319A GB1366319A GB5621371A GB5621371A GB1366319A GB 1366319 A GB1366319 A GB 1366319A GB 5621371 A GB5621371 A GB 5621371A GB 5621371 A GB5621371 A GB 5621371A GB 1366319 A GB1366319 A GB 1366319A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- amino
- theophylline
- reacting
- theohylline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- -1 nitro, amino Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 2
- 229960000278 theophylline Drugs 0.000 abstract 2
- ZZESAIGPDOBLKZ-UHFFFAOYSA-N 8-amino-1,3-dimethyl-7h-purine-2,6-dione Chemical class O=C1N(C)C(=O)N(C)C2=C1NC(N)=N2 ZZESAIGPDOBLKZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000006577 C1-C6 hydroxyalkyl group Chemical group 0.000 abstract 1
- 101100326341 Drosophila melanogaster brun gene Proteins 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 230000000146 antalgic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 230000003182 bronchodilatating effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 230000000916 dilatatory effect Effects 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7043890A FR2116301B1 (enExample) | 1970-12-07 | 1970-12-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1366319A true GB1366319A (en) | 1974-09-11 |
Family
ID=9065323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5621371A Expired GB1366319A (en) | 1970-12-07 | 1971-12-03 | Sa 8-amino-theohylline derivatives process for their preparation and therapeutic compositon containing same |
Country Status (11)
| Country | Link |
|---|---|
| AU (1) | AU3654871A (enExample) |
| BE (1) | BE776278A (enExample) |
| CA (1) | CA925088A (enExample) |
| CH (1) | CH546772A (enExample) |
| DE (1) | DE2160382A1 (enExample) |
| ES (1) | ES397562A1 (enExample) |
| FR (1) | FR2116301B1 (enExample) |
| GB (1) | GB1366319A (enExample) |
| LU (1) | LU64394A1 (enExample) |
| OA (1) | OA03925A (enExample) |
| ZA (1) | ZA718135B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111239060A (zh) * | 2019-01-09 | 2020-06-05 | 北京九强生物技术股份有限公司 | 6-磷酸葡萄糖脱氢酶突变体及其在制备茶碱检测试剂中的用途 |
-
1970
- 1970-12-07 FR FR7043890A patent/FR2116301B1/fr not_active Expired
-
1971
- 1971-11-29 OA OA54423A patent/OA03925A/xx unknown
- 1971-11-29 CH CH1736671A patent/CH546772A/fr not_active IP Right Cessation
- 1971-12-01 ES ES397562A patent/ES397562A1/es not_active Expired
- 1971-12-02 LU LU64394D patent/LU64394A1/xx unknown
- 1971-12-03 GB GB5621371A patent/GB1366319A/en not_active Expired
- 1971-12-06 DE DE19712160382 patent/DE2160382A1/de active Pending
- 1971-12-06 ZA ZA718135A patent/ZA718135B/xx unknown
- 1971-12-06 BE BE776278A patent/BE776278A/xx unknown
- 1971-12-06 AU AU36548/71A patent/AU3654871A/en not_active Expired
- 1971-12-07 CA CA129547A patent/CA925088A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111239060A (zh) * | 2019-01-09 | 2020-06-05 | 北京九强生物技术股份有限公司 | 6-磷酸葡萄糖脱氢酶突变体及其在制备茶碱检测试剂中的用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2116301B1 (enExample) | 1974-08-30 |
| CA925088A (en) | 1973-04-24 |
| CH546772A (fr) | 1974-03-15 |
| OA03925A (fr) | 1975-08-14 |
| LU64394A1 (enExample) | 1972-06-19 |
| DE2160382A1 (de) | 1972-06-22 |
| ES397562A1 (es) | 1974-06-16 |
| BE776278A (fr) | 1972-04-04 |
| FR2116301A1 (enExample) | 1972-07-13 |
| AU3654871A (en) | 1973-06-14 |
| ZA718135B (en) | 1972-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |