GB1360536A - Pyridoxyl-l-aspartic acid salt - Google Patents
Pyridoxyl-l-aspartic acid saltInfo
- Publication number
- GB1360536A GB1360536A GB1950072A GB1950072A GB1360536A GB 1360536 A GB1360536 A GB 1360536A GB 1950072 A GB1950072 A GB 1950072A GB 1950072 A GB1950072 A GB 1950072A GB 1360536 A GB1360536 A GB 1360536A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyridoxyl
- aspastate
- monopotassium
- acid salt
- aspartic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1360536 Pyridoxyl aspastate salt SOC E ETUDES DE PRODUITS CHIMIQUES 30 March 1973 [25 April 1972] 19500/72 Heading C2C Monopotassium pyridoxyl - l - aspastate of formula is prepared by reacting pyridoxal with dipotassium - l - aspastate and reducing in situ with HBH 4 the Schiffs base so formed followed by addition of mineral acid to yield the monopotassium slat. Pharmaceutical compositions in conventional forms having cardiac analeptic activity comprise the above compound and carriers or diluents.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1950072A GB1360536A (en) | 1972-04-25 | 1972-04-25 | Pyridoxyl-l-aspartic acid salt |
FR7310228A FR2181843B1 (en) | 1972-04-25 | 1973-03-22 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1950072A GB1360536A (en) | 1972-04-25 | 1972-04-25 | Pyridoxyl-l-aspartic acid salt |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1360536A true GB1360536A (en) | 1974-07-17 |
Family
ID=10130402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1950072A Expired GB1360536A (en) | 1972-04-25 | 1972-04-25 | Pyridoxyl-l-aspartic acid salt |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR2181843B1 (en) |
GB (1) | GB1360536A (en) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5288716A (en) * | 1987-02-18 | 1994-02-22 | Ulrich Speck | Use of pyridoxine derivatives in the prevention and treatment of hyperlipidaemia and atherosclerosis |
US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
US6339085B1 (en) | 1999-03-08 | 2002-01-15 | The University Of Manitoba | Therapeutics for cardiovascular and related diseases |
US6417204B1 (en) | 2000-07-07 | 2002-07-09 | Medicure International Inc. | Pyridoxine AMD pyridoxal analogues: cardiovascular therapeutics |
US6489345B1 (en) | 1999-07-13 | 2002-12-03 | Medicure, Inc. | Treatment of diabetes and related pathologies |
US6548519B1 (en) | 2001-07-06 | 2003-04-15 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: novel uses |
US6586414B2 (en) | 2000-03-28 | 2003-07-01 | Medicure International Inc. | Treatment of cerebrovascular disease |
US6605612B2 (en) | 2000-02-29 | 2003-08-12 | Medicure International Inc. | Cardioprotective phosohonates and malonates |
US6677356B1 (en) | 1999-08-24 | 2004-01-13 | Medicure International Inc. | Treatment of cardiovascular and related pathologies |
US6897228B2 (en) | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
US7812037B2 (en) | 2004-10-28 | 2010-10-12 | Medicure International, Inc. | Dual antiplatelet/anticoagulant pyridoxine analogs |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2542869A (en) * | 1948-03-19 | 1951-02-20 | Merck & Co Inc | N-pyridoxyl-amino acids and process of preparing the same |
-
1972
- 1972-04-25 GB GB1950072A patent/GB1360536A/en not_active Expired
-
1973
- 1973-03-22 FR FR7310228A patent/FR2181843B1/fr not_active Expired
Cited By (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5288716A (en) * | 1987-02-18 | 1994-02-22 | Ulrich Speck | Use of pyridoxine derivatives in the prevention and treatment of hyperlipidaemia and atherosclerosis |
US6066659A (en) * | 1987-02-18 | 2000-05-23 | Steigerwald Arzneimittelwerk Gmbh | Use of pyridoxine derivatives in the prevention and treatment of hyperlipidaemia and atherosclerosis |
US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
US7230009B2 (en) | 1999-03-08 | 2007-06-12 | Medicure, Inc. | Pyridoxal analogues and methods of treatment |
US6339085B1 (en) | 1999-03-08 | 2002-01-15 | The University Of Manitoba | Therapeutics for cardiovascular and related diseases |
US6890943B2 (en) | 1999-03-08 | 2005-05-10 | Medicure Inc. | Pyridoxal analogues and methods of treatment |
US6489345B1 (en) | 1999-07-13 | 2002-12-03 | Medicure, Inc. | Treatment of diabetes and related pathologies |
US6677356B1 (en) | 1999-08-24 | 2004-01-13 | Medicure International Inc. | Treatment of cardiovascular and related pathologies |
US7125889B2 (en) | 1999-08-24 | 2006-10-24 | Medicure International Inc. | Treating of cardiovascular and related pathologies |
US7144892B2 (en) | 1999-08-24 | 2006-12-05 | Merrill Lynch Capital Canada Inc. | Treatment of cardiovascular and related pathologies |
US7148233B2 (en) | 1999-08-24 | 2006-12-12 | Merrill Lynch Capital Canada Inc. | Treatment of cardiovascular and related pathologies |
US7132430B2 (en) | 1999-08-24 | 2006-11-07 | Medicure International Inc. | Treatment of cardiovascular and related pathologies |
US7115626B2 (en) | 1999-08-24 | 2006-10-03 | Medicure International Inc. | Treatment of cardiovascular and related pathologies |
US7115625B2 (en) | 1999-08-24 | 2006-10-03 | Medicure International Inc. | Treatment of cardiovascular and related pathologies |
US6605612B2 (en) | 2000-02-29 | 2003-08-12 | Medicure International Inc. | Cardioprotective phosohonates and malonates |
US6667315B2 (en) | 2000-02-29 | 2003-12-23 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
US6780997B2 (en) | 2000-02-29 | 2004-08-24 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
US6867215B2 (en) | 2000-02-29 | 2005-03-15 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
US7105673B2 (en) | 2000-02-29 | 2006-09-12 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
US6861439B2 (en) | 2000-03-28 | 2005-03-01 | Medicure International, Inc. | Treatment of cerebrovascular disease |
US6586414B2 (en) | 2000-03-28 | 2003-07-01 | Medicure International Inc. | Treatment of cerebrovascular disease |
US6897228B2 (en) | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
US6417204B1 (en) | 2000-07-07 | 2002-07-09 | Medicure International Inc. | Pyridoxine AMD pyridoxal analogues: cardiovascular therapeutics |
US6548519B1 (en) | 2001-07-06 | 2003-04-15 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: novel uses |
US7812037B2 (en) | 2004-10-28 | 2010-10-12 | Medicure International, Inc. | Dual antiplatelet/anticoagulant pyridoxine analogs |
Also Published As
Publication number | Publication date |
---|---|
FR2181843A1 (en) | 1973-12-07 |
FR2181843B1 (en) | 1976-05-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES344357A1 (en) | Cyclopropanecarboxylic acid esters | |
GB1325192A (en) | Phloroglucinol derivatives | |
GB1360536A (en) | Pyridoxyl-l-aspartic acid salt | |
GB1382782A (en) | Alkylarylketones processes for their preparation and compositions incorporating them | |
GB1380225A (en) | Biphenylyl- alkanoylaminopyridines and acid addition salts thereof | |
GB1308028A (en) | Thiazolylbenzoic acid derivatives and a process for their manufactur | |
GB1336037A (en) | Mercapto carboxylic acid esters | |
IE36127L (en) | 3-benzylpyridines | |
GB1325386A (en) | Quinazoline derivatives processes for producing them and compositions containing them | |
GB1343587A (en) | Process for the preparation of derivatives of beta-phenylpyruvic acid | |
GB1292410A (en) | Thienobenzothiazepine derivatives | |
GB1411700A (en) | Penicillins and production thereof | |
GB1446789A (en) | Production of benzenesulphonamides | |
GB1412932A (en) | Pharmaceutically active leurosine derivatives and preparation thereof | |
GB1259685A (en) | Amino-pyrimidine derivatives | |
GB1366241A (en) | Phenylpyridylallylamines and a process for their preparation | |
GB1429697A (en) | Method for producing isonitrosomalonic esters | |
GB1224619A (en) | DERIVATIVES OF alpha-AMINOPENICILLINS | |
GB1284516A (en) | Aminopropionyl derivatives of 2,3-diphenyl-cyclopropylamine | |
GB1333510A (en) | Malonyl urea derivatives process for their preparation and compositions incorporating them | |
GB1261594A (en) | Novel 3-arylimino-4,5-dichloro-1,2-dithioles, processes for their production and compositions containing them | |
GB1341612A (en) | Theophylline isobutyrate salts and process for the preparation thereof | |
GB1271016A (en) | Novel pyrrolidine derivatives, and processes for their preparation | |
GB1333524A (en) | Penicilloic acid derivatives | |
GB1388325A (en) | Benzodioxan derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |