GB1356937A - Pyrimido-isoquinolines - Google Patents
Pyrimido-isoquinolinesInfo
- Publication number
- GB1356937A GB1356937A GB4140270A GB4140270A GB1356937A GB 1356937 A GB1356937 A GB 1356937A GB 4140270 A GB4140270 A GB 4140270A GB 4140270 A GB4140270 A GB 4140270A GB 1356937 A GB1356937 A GB 1356937A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyrimido
- compounds
- aug
- isoquinolines
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RDBTWTJYBFGUOB-UHFFFAOYSA-N pyrido[3,4-f]quinazoline Chemical class N1=CN=CC2=C(C=NC=C3)C3=CC=C21 RDBTWTJYBFGUOB-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- SXULEUOIZFHQLM-UHFFFAOYSA-N 1,3,4,6,7,11b-hexahydropyrimido[2,1-a]isoquinolin-2-one Chemical compound O=C1NC2N(CCC3=CC=CC=C23)CC1 SXULEUOIZFHQLM-UHFFFAOYSA-N 0.000 abstract 1
- KFCJKQZKHMRYQF-UHFFFAOYSA-N 3,4-dihydroisoquinolin-1-amine Chemical compound C1=CC=C2C(N)=NCCC2=C1 KFCJKQZKHMRYQF-UHFFFAOYSA-N 0.000 abstract 1
- BGAJZISBCWKHSD-UHFFFAOYSA-N 3-(1-iminoisoquinolin-2-yl)propanoic acid Chemical compound N=C1N(C=CC2=CC=CC=C12)CCC(=O)O BGAJZISBCWKHSD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000002456 anti-arthritic effect Effects 0.000 abstract 1
- OSILBMSORKFRTB-UHFFFAOYSA-N isoquinolin-1-amine Chemical compound C1=CC=C2C(N)=NC=CC2=C1 OSILBMSORKFRTB-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000269 nucleophilic effect Effects 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4140270A GB1356937A (en) | 1970-08-27 | 1970-08-27 | Pyrimido-isoquinolines |
| CA121,468A CA977343A (en) | 1970-08-27 | 1971-08-26 | Heterocyclic compounds |
| IE1082/71A IE35570B1 (en) | 1970-08-27 | 1971-08-26 | Pyrimido isoquinolines |
| FR7131030A FR2103559B1 (enExample) | 1970-08-27 | 1971-08-26 | |
| AU32762/71A AU465829B2 (en) | 1970-08-27 | 1971-08-26 | Heterocyclic compounds |
| DE19712142792 DE2142792A1 (de) | 1970-08-27 | 1971-08-26 | Heterocyclische Verbindungen |
| NL7111759A NL7111759A (enExample) | 1970-08-27 | 1971-08-26 | |
| US00175329A US3792050A (en) | 1970-08-27 | 1971-08-26 | 2-oxo-2h-pyrimido(2,1-a)isoquinoline |
| ES394546A ES394546A1 (es) | 1970-08-27 | 1971-08-26 | Procedimiento para la preparacion de pirimido (2 1-a) iso- quinoleinas. |
| IL37588A IL37588A (en) | 1970-08-27 | 1971-08-26 | 2h-pyrimido (2,1-a) isoquinolin-2-ones,their preparation and pharmaceutical compositions containing them |
| SE7110810A SE373138B (enExample) | 1970-08-27 | 1971-08-26 | |
| AR237590A AR192890A1 (es) | 1970-08-27 | 1971-08-26 | Un procedimiento para la preparacion de pirimida(2,1-a)isoquinolinas |
| ZA715701A ZA715701B (en) | 1970-08-27 | 1971-08-26 | Heterocyclic compounds |
| HUWE000443 HU164176B (enExample) | 1970-08-27 | 1971-08-27 | |
| BE771911A BE771911A (fr) | 1970-08-27 | 1971-08-27 | Composes heterocycliques |
| AR241935A AR193522A1 (es) | 1970-08-27 | 1972-05-11 | Un procedimiento para la preparacion de pirimido(2,1-a)isoquinolinas |
| AR241934A AR195669A1 (es) | 1970-08-27 | 1972-05-11 | Un procedimiento para la preparacion de pirimido <2,1-a> isoquinolinas |
| US306716A US3876788A (en) | 1970-08-27 | 1972-11-15 | Heterocyclic compounds in the treatment of inflammatory of arthritic conditions |
| ES422327A ES422327A1 (es) | 1970-08-27 | 1974-01-16 | Un procedimiento para la preparacion de pirimido (2,1-a) i-soquinoleinas. |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4140270A GB1356937A (en) | 1970-08-27 | 1970-08-27 | Pyrimido-isoquinolines |
| GB5678170 | 1970-11-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1356937A true GB1356937A (en) | 1974-06-19 |
Family
ID=26264669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4140270A Expired GB1356937A (en) | 1970-08-27 | 1970-08-27 | Pyrimido-isoquinolines |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3792050A (enExample) |
| AR (3) | AR192890A1 (enExample) |
| BE (1) | BE771911A (enExample) |
| CA (1) | CA977343A (enExample) |
| DE (1) | DE2142792A1 (enExample) |
| ES (2) | ES394546A1 (enExample) |
| FR (1) | FR2103559B1 (enExample) |
| GB (1) | GB1356937A (enExample) |
| IE (1) | IE35570B1 (enExample) |
| IL (1) | IL37588A (enExample) |
| NL (1) | NL7111759A (enExample) |
| SE (1) | SE373138B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3868378A (en) * | 1973-06-06 | 1975-02-25 | Morton Norwich Products Inc | Imidazo {8 4,5-f{9 {0 quinolin-9-ols |
| US3919238A (en) * | 1973-06-06 | 1975-11-11 | Morton Norwich Products Inc | 9-(Substituted amino)imidazo(4,5-f) quinolines |
| US4017625A (en) * | 1975-08-01 | 1977-04-12 | Pfizer Inc. | Anti-allergic N-(5-tetrazolyl)-1-oxo-1H-6-alkoxypyrimido-[1,2-a]quinoline-2-carboxamides and intermediates therefor |
| US4127720A (en) * | 1977-09-21 | 1978-11-28 | Bristol-Myers Company | Pyrimido[2,1-a]isoquinoline derivatives having antiallergy activity |
-
1970
- 1970-08-27 GB GB4140270A patent/GB1356937A/en not_active Expired
-
1971
- 1971-08-26 US US00175329A patent/US3792050A/en not_active Expired - Lifetime
- 1971-08-26 FR FR7131030A patent/FR2103559B1/fr not_active Expired
- 1971-08-26 IE IE1082/71A patent/IE35570B1/xx unknown
- 1971-08-26 NL NL7111759A patent/NL7111759A/xx unknown
- 1971-08-26 SE SE7110810A patent/SE373138B/xx unknown
- 1971-08-26 IL IL37588A patent/IL37588A/en unknown
- 1971-08-26 ES ES394546A patent/ES394546A1/es not_active Expired
- 1971-08-26 DE DE19712142792 patent/DE2142792A1/de active Pending
- 1971-08-26 CA CA121,468A patent/CA977343A/en not_active Expired
- 1971-08-26 AR AR237590A patent/AR192890A1/es active
- 1971-08-27 BE BE771911A patent/BE771911A/xx unknown
-
1972
- 1972-05-11 AR AR241935A patent/AR193522A1/es active
- 1972-05-11 AR AR241934A patent/AR195669A1/es active
-
1974
- 1974-01-16 ES ES422327A patent/ES422327A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES422327A1 (es) | 1976-08-01 |
| FR2103559B1 (enExample) | 1974-09-06 |
| NL7111759A (enExample) | 1972-02-29 |
| SE373138B (enExample) | 1975-01-27 |
| DE2142792A1 (de) | 1972-03-02 |
| US3792050A (en) | 1974-02-12 |
| CA977343A (en) | 1975-11-04 |
| FR2103559A1 (enExample) | 1972-04-14 |
| BE771911A (fr) | 1972-12-28 |
| IE35570B1 (en) | 1976-03-18 |
| AR195669A1 (es) | 1973-10-31 |
| IL37588A0 (en) | 1971-11-29 |
| AR192890A1 (es) | 1973-03-21 |
| AR193522A1 (es) | 1973-04-30 |
| ES394546A1 (es) | 1974-09-01 |
| IL37588A (en) | 1974-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |