GB1356581A - Cyclopentane derivatives - Google Patents

Cyclopentane derivatives

Info

Publication number
GB1356581A
GB1356581A GB48131/70*2A GB4813170A GB1356581A GB 1356581 A GB1356581 A GB 1356581A GB 4813170 A GB4813170 A GB 4813170A GB 1356581 A GB1356581 A GB 1356581A
Authority
GB
United Kingdom
Prior art keywords
tetrahydropyran
yloxy
trans
reacting
cis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB48131/70*2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Priority to GB48131/70*2A priority Critical patent/GB1356581A/en
Priority to ZA716270A priority patent/ZA716270B/xx
Priority to HUIE478A priority patent/HU163414B/hu
Priority to IL37821A priority patent/IL37821A0/xx
Priority to ZM142/71A priority patent/ZM14271A1/xx
Priority to SU1702653A priority patent/SU439962A1/ru
Priority to AU34335/71A priority patent/AU3433571A/en
Priority to ES395814A priority patent/ES395814A1/es
Priority to NL7113880A priority patent/NL7113880A/xx
Priority to BE773728A priority patent/BE773728A/xx
Priority to DE19712150361 priority patent/DE2150361A1/de
Priority to FR7136366A priority patent/FR2110335B1/fr
Publication of GB1356581A publication Critical patent/GB1356581A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4015—Esters of acyclic unsaturated acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB48131/70*2A 1970-10-09 1970-10-09 Cyclopentane derivatives Expired GB1356581A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
GB48131/70*2A GB1356581A (en) 1970-10-09 1970-10-09 Cyclopentane derivatives
ZA716270A ZA716270B (en) 1970-10-09 1971-09-20 Cyclopentane derivatives
HUIE478A HU163414B (enExample) 1970-10-09 1971-09-21
IL37821A IL37821A0 (en) 1970-10-09 1971-09-28 Cyclopentane derivatives
ZM142/71A ZM14271A1 (en) 1970-10-09 1971-10-01 Cyclopentane derivatives
SU1702653A SU439962A1 (ru) 1971-10-04 Способ получени производных простанкарбоновой кислоты
AU34335/71A AU3433571A (en) 1970-10-09 1971-10-07 Cyclopentane derivatives
ES395814A ES395814A1 (es) 1970-10-09 1971-10-07 Procedimiento para la obtencion de derivados del acido prostanoico.
NL7113880A NL7113880A (enExample) 1970-10-09 1971-10-08
BE773728A BE773728A (fr) 1970-10-09 1971-10-08 Derives du cyclopentane
DE19712150361 DE2150361A1 (de) 1970-10-09 1971-10-08 Prostanoesaeurederivate
FR7136366A FR2110335B1 (enExample) 1970-10-09 1971-10-08

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB48131/70*2A GB1356581A (en) 1970-10-09 1970-10-09 Cyclopentane derivatives
GB181471 1971-01-14
GB554371 1971-02-26

Publications (1)

Publication Number Publication Date
GB1356581A true GB1356581A (en) 1974-06-12

Family

ID=27253947

Family Applications (1)

Application Number Title Priority Date Filing Date
GB48131/70*2A Expired GB1356581A (en) 1970-10-09 1970-10-09 Cyclopentane derivatives

Country Status (9)

Country Link
BE (1) BE773728A (enExample)
DE (1) DE2150361A1 (enExample)
ES (1) ES395814A1 (enExample)
FR (1) FR2110335B1 (enExample)
GB (1) GB1356581A (enExample)
HU (1) HU163414B (enExample)
IL (1) IL37821A0 (enExample)
NL (1) NL7113880A (enExample)
ZM (1) ZM14271A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015134801A (ja) * 2015-03-09 2015-07-27 テックフィールズ バイオケム カンパニー リミテッド 非常に高い皮膚浸透率を有するプロスタグランジン及び関連化合物の正荷電水溶性プロドラッグ
JP2016074730A (ja) * 2016-01-08 2016-05-12 テックフィールズ バイオケム カンパニー リミテッド 非常に高い皮膚浸透率を有するプロスタグランジン及び関連化合物の正荷電水溶性プロドラッグ
JP7141025B1 (ja) 2021-11-11 2022-09-22 エルデシエロ プライベート リミテッド 化合物、組成物、方法、及び製造方法
US11555014B2 (en) 2006-10-02 2023-01-17 Techfields Pharma Co., Ltd. High penetration prodrug compositions of prostaglandins and related compounds

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887587A (en) * 1972-04-17 1975-06-03 Pfizer Synthesis of prostaglandins of the one-series
DE2317019A1 (de) * 1972-04-27 1973-11-08 Upjohn Co Neue 4,5-didehydro-prostaglandine
US3954741A (en) * 1972-06-07 1976-05-04 Pfizer Inc. N-substituted prostaglandin carboxamides
GB1520522A (en) * 1975-06-16 1978-08-09 Ono Pharmaceutical Co 16-methyleneprostaglandins
US5236907A (en) * 1988-10-01 1993-08-17 R-Tech Ueno Ltd. Ocular hypotensive agents
US6420422B1 (en) 1987-09-18 2002-07-16 Sucampo Pharmaceuticals, Inc. Ocular hypotensive agents
ATE111736T1 (de) * 1988-10-01 1994-10-15 R Tech Ueno Ltd Okulare hypotensive mittel.
US5194429A (en) * 1988-10-01 1993-03-16 K.K. Ueno Seiyaku Oyo Kenkyujo Ocular hypotensive agents

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11555014B2 (en) 2006-10-02 2023-01-17 Techfields Pharma Co., Ltd. High penetration prodrug compositions of prostaglandins and related compounds
JP2015134801A (ja) * 2015-03-09 2015-07-27 テックフィールズ バイオケム カンパニー リミテッド 非常に高い皮膚浸透率を有するプロスタグランジン及び関連化合物の正荷電水溶性プロドラッグ
JP2016074730A (ja) * 2016-01-08 2016-05-12 テックフィールズ バイオケム カンパニー リミテッド 非常に高い皮膚浸透率を有するプロスタグランジン及び関連化合物の正荷電水溶性プロドラッグ
JP7141025B1 (ja) 2021-11-11 2022-09-22 エルデシエロ プライベート リミテッド 化合物、組成物、方法、及び製造方法
WO2023085135A1 (ja) * 2021-11-11 2023-05-19 エルデシエロ プライベート リミテッド 化合物、組成物、方法、及び製造方法
JP2023071523A (ja) * 2021-11-11 2023-05-23 エルデシエロ プライベート リミテッド 化合物、組成物、方法、及び製造方法
EP4431492A4 (en) * 2021-11-11 2025-11-05 Warrantee Inc COMPOUND, COMPOSITION, PROCESS AND PRODUCTION PROCESS

Also Published As

Publication number Publication date
DE2150361A1 (de) 1972-04-13
FR2110335B1 (enExample) 1975-06-06
ZM14271A1 (en) 1972-06-21
SU439962A3 (ru) 1974-08-15
BE773728A (fr) 1972-04-10
FR2110335A1 (enExample) 1972-06-02
HU163414B (enExample) 1973-08-28
ES395814A1 (es) 1975-03-01
NL7113880A (enExample) 1972-04-11
IL37821A0 (en) 1971-11-29

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Legal Events

Date Code Title Description
CSNS Application of which complete specification have been accepted and published, but patent is not sealed