GB1356076A - Attenuated viruses - Google Patents

Attenuated viruses

Info

Publication number
GB1356076A
GB1356076A GB5672372A GB5672372A GB1356076A GB 1356076 A GB1356076 A GB 1356076A GB 5672372 A GB5672372 A GB 5672372A GB 5672372 A GB5672372 A GB 5672372A GB 1356076 A GB1356076 A GB 1356076A
Authority
GB
United Kingdom
Prior art keywords
virus
attenuated
cattle
dec
diluent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5672372A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB1356076A publication Critical patent/GB1356076A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16732Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16761Methods of inactivation or attenuation
    • C12N2710/16764Methods of inactivation or attenuation by serial passage

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

1356076 Attenuated virus vaccine; interferon induction BAYER AG 8 Dec 1972 [10 Dec 1971] 56723/72 Heading A5B A virus is attenuated by serial passage on tissue cultures until it will stimulate interferon production without producing specific immunity to the orginial virus. The virus may be I.P.V. virus (otherwise known as infectious pustular vulvovaginitis, Exanthema coitale vesiculosum bovis or cattle blister rash), pseudorabies virus or influenza virus. It may be passaged on calf kidney, suprarenal or testicular tissue. The attenuated virus may be compounded with a liquified gaseous diluent, isotonic fluid, a buffer solution, a liquid having a molecular weight of 200 or more or a solid diluent. The composition may be used as tablets, pills, dragees, capsules, ampoules for intramuscular injection or nasal sprays, or suppositories. They may be applied to cattle or pigs.
GB5672372A 1971-12-10 1972-12-08 Attenuated viruses Expired GB1356076A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2161344A DE2161344C3 (en) 1971-12-10 1971-12-10 Production of virus strains which stimulate the natural defense mechanisms of a host organism without simultaneously having an antigenic effect and medicaments for the prophylaxis and treatment of viral and bacterial infections in humans and animals, containing such a virus strain

Publications (1)

Publication Number Publication Date
GB1356076A true GB1356076A (en) 1974-06-12

Family

ID=5827622

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5672372A Expired GB1356076A (en) 1971-12-10 1972-12-08 Attenuated viruses

Country Status (21)

Country Link
JP (2) JPS6011013B2 (en)
AR (1) AR204075A1 (en)
AT (1) AT326817B (en)
AU (1) AU473209B2 (en)
BE (1) BE792484A (en)
BG (1) BG21417A3 (en)
CA (1) CA988848A (en)
CH (1) CH577558A5 (en)
CS (1) CS189587B2 (en)
DD (1) DD108115A5 (en)
DE (1) DE2161344C3 (en)
DK (1) DK143201C (en)
ES (1) ES409464A1 (en)
FR (1) FR2162637B1 (en)
GB (1) GB1356076A (en)
HU (1) HU167086B (en)
IE (1) IE36995B1 (en)
NL (1) NL178014C (en)
PH (1) PH12597A (en)
SE (1) SE8400283L (en)
ZA (1) ZA728709B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0063657A1 (en) * 1981-04-29 1982-11-03 Merck & Co. Inc. Topical application of interferon inducers

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0063657A1 (en) * 1981-04-29 1982-11-03 Merck & Co. Inc. Topical application of interferon inducers

Also Published As

Publication number Publication date
ATA1041972A (en) 1975-03-15
DE2161344B2 (en) 1980-05-08
DE2161344C3 (en) 1986-10-02
CS189587B2 (en) 1979-04-30
JPS6011013B2 (en) 1985-03-22
AT326817B (en) 1975-12-29
NL178014B (en) 1985-08-01
SE8400283D0 (en) 1984-01-20
AR204075A1 (en) 1975-11-20
BG21417A3 (en) 1976-05-20
NL7216628A (en) 1973-06-13
ZA728709B (en) 1973-08-29
HU167086B (en) 1975-08-28
SU439956A3 (en) 1974-08-15
SE8400283L (en) 1984-01-20
JPS5924137B2 (en) 1984-06-07
FR2162637B1 (en) 1976-07-02
DK143201C (en) 1981-12-14
JPS4862912A (en) 1973-09-01
DK143201B (en) 1981-07-20
FR2162637A1 (en) 1973-07-20
AU4992072A (en) 1974-06-13
DE2161344A1 (en) 1973-06-20
IE36995L (en) 1973-06-10
AU473209B2 (en) 1976-06-17
IE36995B1 (en) 1977-04-13
PH12597A (en) 1979-06-27
CA988848A (en) 1976-05-11
JPS4862919A (en) 1973-09-01
BE792484A (en) 1973-06-08
ES409464A1 (en) 1976-03-16
NL178014C (en) 1986-01-02
DD108115A5 (en) 1974-09-05
CH577558A5 (en) 1976-07-15

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee