GB1336949A - Adenosine derivatives - Google Patents

Adenosine derivatives

Info

Publication number
GB1336949A
GB1336949A GB3096772A GB3096772A GB1336949A GB 1336949 A GB1336949 A GB 1336949A GB 3096772 A GB3096772 A GB 3096772A GB 3096772 A GB3096772 A GB 3096772A GB 1336949 A GB1336949 A GB 1336949A
Authority
GB
United Kingdom
Prior art keywords
phenyl
july
methoxy
adenosine derivatives
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3096772A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2133473A external-priority patent/DE2133473A1/en
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1336949A publication Critical patent/GB1336949A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

1336949 Adenosine derivatives BOEHRINGER MANNHEIM GmbH 3 July 1972 [6 July 1971] 30967/72 Heading C2C Novel compounds I and salts thereof in which A is C 1-5 alkyl or C 1-5 alkoxy, X is a bond or oxygen and n is 1 to 5 are prepared by reacting a 6-halopurine riboside with an amine of general Formula III The hydroxyl groups in the ribose residue are blocked by protective groups. Amines used are 2 - (2, 3 or 4 - methoxy - phenyl)cyclohexylamine, 2 - (2 - methyl - phenyl)cyclohexyl- or pentylamine or 2 - (3 - methoxy - phenyl)cyclopentylamine. Compounds I have a beneficial action on blood vessels and circulation and also lower the level of lipids in serum and they form with a solid or liquid diluent or carrier a pharmaceutical composition which may be administered orally or parenterally.
GB3096772A 1971-07-06 1972-07-03 Adenosine derivatives Expired GB1336949A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2133473A DE2133473A1 (en) 1967-06-08 1971-07-06 Adenosine derivs - prepd by reaction 6-halo-purine riboside with amines, show activity on blood vessels and circulation and lipid-

Publications (1)

Publication Number Publication Date
GB1336949A true GB1336949A (en) 1973-11-14

Family

ID=5812772

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3096772A Expired GB1336949A (en) 1971-07-06 1972-07-03 Adenosine derivatives

Country Status (6)

Country Link
AT (1) AT317445B (en)
CA (1) CA967954A (en)
CH (1) CH564032A5 (en)
GB (1) GB1336949A (en)
NL (1) NL7209418A (en)
ZA (1) ZA724633B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0232813A2 (en) * 1986-01-31 1987-08-19 Warner-Lambert Company N6-substituted Adenosines

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0232813A2 (en) * 1986-01-31 1987-08-19 Warner-Lambert Company N6-substituted Adenosines
EP0232813A3 (en) * 1986-01-31 1989-03-22 Warner-Lambert Company N6-substituted adenosines

Also Published As

Publication number Publication date
CA967954A (en) 1975-05-20
CH564032A5 (en) 1975-07-15
ZA724633B (en) 1973-05-30
NL7209418A (en) 1973-01-09
AT317445B (en) 1974-08-26

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee