GB1355033A - Antimalarial medicines comprising thiazolyl thioureas - Google Patents

Antimalarial medicines comprising thiazolyl thioureas

Info

Publication number
GB1355033A
GB1355033A GB2108473A GB2108471A GB1355033A GB 1355033 A GB1355033 A GB 1355033A GB 2108473 A GB2108473 A GB 2108473A GB 2108471 A GB2108471 A GB 2108471A GB 1355033 A GB1355033 A GB 1355033A
Authority
GB
United Kingdom
Prior art keywords
thioureas
thiazolyl
alkyl
antimalarial medicines
july
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2108473A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1355033A publication Critical patent/GB1355033A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/48Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

1355033 Antimalarial medicines F HOFFMANN-LA ROCHE & CO AG 23 July 1971 [24 July 1970] 21084/73 Divided out of 1330930 Heading A5B Compositions in unit dosage form for treating or preventing malaria comprise a carrier and a compound (or a salt thereof) of the formula: wherein R<SP>1</SP> is H or C 1-4 alkyl, R<SP>2</SP>=C 1-4 alkyl or aryl and R<SP>3</SP> is H or C 1-4 alkyl, provided that when R<SP>3</SP> is H, R<SP>1</SP> and R<SP>2</SP> are not both ethyl and when R<SP>3</SP> is CH 3 , R<SP>1</SP> and R<SP>2</SP> are not both ethyl or methyl. They may be in conventional forms for oral, rectal and parenteral administration.
GB2108473A 1970-07-24 1971-07-23 Antimalarial medicines comprising thiazolyl thioureas Expired GB1355033A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1123970A CH543535A (en) 1970-07-24 1970-07-24 Process for the preparation of thiazole derivatives

Publications (1)

Publication Number Publication Date
GB1355033A true GB1355033A (en) 1974-06-05

Family

ID=4371497

Family Applications (2)

Application Number Title Priority Date Filing Date
GB2108473A Expired GB1355033A (en) 1970-07-24 1971-07-23 Antimalarial medicines comprising thiazolyl thioureas
GB3475571A Expired GB1330930A (en) 1970-07-24 1971-07-23 Thiazole derivatives and a process for the manufacture thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB3475571A Expired GB1330930A (en) 1970-07-24 1971-07-23 Thiazole derivatives and a process for the manufacture thereof

Country Status (15)

Country Link
AR (1) AR192413A1 (en)
AT (2) AT309420B (en)
AU (1) AU3041871A (en)
BE (1) BE770402A (en)
BR (1) BR7104636D0 (en)
CA (1) CA954514A (en)
CH (1) CH543535A (en)
DE (1) DE2137046A1 (en)
ES (1) ES393554A1 (en)
FR (2) FR2100949B1 (en)
GB (2) GB1355033A (en)
HU (1) HU163282B (en)
IL (1) IL37234A0 (en)
NL (1) NL7109995A (en)
ZA (1) ZA714030B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108938628A (en) * 2018-08-29 2018-12-07 锁浩 A kind of composition and its application with anti-malarial activity

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL102548A (en) * 1991-08-02 1998-08-16 Medivir Ab Thiourea derivatives for use in the preparation of medicaments for the inhibition of hiv and the treatment of aids and some such novel compounds
US5593993A (en) * 1991-08-02 1997-01-14 Medivir Ab Method for inhibition of HIV related viruses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1265810A (en) * 1956-04-13 1961-07-07 Merck & Co Inc Process for the preparation of urea and thiourea derivatives
FR1533184A (en) * 1965-04-06 1968-07-19 Pechiney Saint Gobain Thiazole derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108938628A (en) * 2018-08-29 2018-12-07 锁浩 A kind of composition and its application with anti-malarial activity

Also Published As

Publication number Publication date
CA954514A (en) 1974-09-10
FR2100949B1 (en) 1975-02-07
FR2158578A1 (en) 1973-06-15
AU3041871A (en) 1973-01-04
BR7104636D0 (en) 1973-03-08
BE770402A (en) 1972-01-24
AT309420B (en) 1973-08-27
DE2137046A1 (en) 1972-01-27
HU163282B (en) 1973-07-28
CH543535A (en) 1973-10-31
ZA714030B (en) 1972-03-29
AT315168B (en) 1974-05-10
IL37234A0 (en) 1971-10-20
NL7109995A (en) 1972-01-26
FR2158578B1 (en) 1976-03-05
ES393554A1 (en) 1974-11-16
FR2100949A1 (en) 1972-03-24
AR192413A1 (en) 1973-02-21
GB1330930A (en) 1973-09-19

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees