GB1354216A - Substituted isoquinolines and a process for the preparation thereof - Google Patents
Substituted isoquinolines and a process for the preparation thereofInfo
- Publication number
- GB1354216A GB1354216A GB4444172A GB4444172A GB1354216A GB 1354216 A GB1354216 A GB 1354216A GB 4444172 A GB4444172 A GB 4444172A GB 4444172 A GB4444172 A GB 4444172A GB 1354216 A GB1354216 A GB 1354216A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- dialkoxy
- compounds
- substituted
- sept
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002537 isoquinolines Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000006555 (C3-C5) cycloalkyl group Chemical group 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical compound OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 abstract 2
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical group 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- VDBNYAPERZTOOF-UHFFFAOYSA-N isoquinolin-1(2H)-one Chemical compound C1=CC=C2C(=O)NC=CC2=C1 VDBNYAPERZTOOF-UHFFFAOYSA-N 0.000 abstract 1
- -1 methylenedioxy Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000002923 oximes Chemical class 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 229960003424 phenylacetic acid Drugs 0.000 abstract 1
- 239000003279 phenylacetic acid Substances 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical compound [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18419771A | 1971-09-27 | 1971-09-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1354216A true GB1354216A (en) | 1974-06-05 |
Family
ID=22675930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4444172A Expired GB1354216A (en) | 1971-09-27 | 1972-09-26 | Substituted isoquinolines and a process for the preparation thereof |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3798225A (en:Method) |
| JP (1) | JPS4947377A (en:Method) |
| AU (1) | AU462564B2 (en:Method) |
| BE (1) | BE789290A (en:Method) |
| CA (1) | CA981685A (en:Method) |
| CH (2) | CH586204A5 (en:Method) |
| DE (1) | DE2247374A1 (en:Method) |
| DK (1) | DK136186B (en:Method) |
| FR (1) | FR2154565B1 (en:Method) |
| GB (1) | GB1354216A (en:Method) |
| NL (1) | NL7213084A (en:Method) |
| SE (2) | SE376417B (en:Method) |
| ZA (1) | ZA726498B (en:Method) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3962254A (en) * | 1974-03-28 | 1976-06-08 | Marion Laboratories, Inc. | N-substituted-5,6-dihydroxycyclopentano[h]-1,2,3,4-tetrahydroisoquinolines and ethers and esters thereof |
| US4315046A (en) * | 1980-07-17 | 1982-02-09 | General Electric Company | Process for securing primerless adhesion of silicone resin coating composition to cast acrylics |
| US4880817A (en) * | 1987-06-09 | 1989-11-14 | Ortho Pharmaceutical Corporation | O-functionalized derivatives of substituted isoquinolin-3-ols having cardiotonic and/or phosphodiesterase fraction III inhibiting properties and/or renal vasodilating properties |
| US20060148848A1 (en) * | 2002-07-02 | 2006-07-06 | Qlt, Inc. | Compounds and methods for treating cancer and inflammation |
| US7286111B2 (en) * | 2003-11-13 | 2007-10-23 | Eastman Kodak Company | Apparatus for electro-optically writing a display |
-
0
- BE BE789290D patent/BE789290A/xx unknown
-
1971
- 1971-09-27 US US00184197A patent/US3798225A/en not_active Expired - Lifetime
-
1972
- 1972-07-04 CA CA146,296A patent/CA981685A/en not_active Expired
- 1972-09-21 AU AU46941/72A patent/AU462564B2/en not_active Expired
- 1972-09-22 ZA ZA726498A patent/ZA726498B/xx unknown
- 1972-09-25 FR FR7233834A patent/FR2154565B1/fr not_active Expired
- 1972-09-26 GB GB4444172A patent/GB1354216A/en not_active Expired
- 1972-09-26 DK DK475972AA patent/DK136186B/da unknown
- 1972-09-26 JP JP47095852A patent/JPS4947377A/ja active Pending
- 1972-09-26 SE SE7212438A patent/SE376417B/xx unknown
- 1972-09-27 NL NL7213084A patent/NL7213084A/xx not_active Application Discontinuation
- 1972-09-27 CH CH1132976A patent/CH586204A5/xx not_active IP Right Cessation
- 1972-09-27 CH CH1407872A patent/CH585719A5/xx not_active IP Right Cessation
- 1972-09-27 DE DE19722247374 patent/DE2247374A1/de active Pending
-
1975
- 1975-01-07 SE SE7500122A patent/SE7500122L/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US3798225A (en) | 1974-03-19 |
| DK136186B (da) | 1977-08-29 |
| DK136186C (en:Method) | 1978-01-30 |
| DE2247374A1 (de) | 1973-04-05 |
| AU4694172A (en) | 1974-03-28 |
| CH585719A5 (en:Method) | 1977-03-15 |
| JPS4947377A (en:Method) | 1974-05-08 |
| SE7500122L (en:Method) | 1975-01-07 |
| FR2154565A1 (en:Method) | 1973-05-11 |
| AU462564B2 (en) | 1975-06-26 |
| CA981685A (en) | 1976-01-13 |
| BE789290A (fr) | 1973-03-26 |
| ZA726498B (en) | 1973-06-27 |
| FR2154565B1 (en:Method) | 1976-05-21 |
| NL7213084A (en:Method) | 1973-03-29 |
| CH586204A5 (en:Method) | 1977-03-31 |
| SE376417B (en:Method) | 1975-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |