GB1353536A - Antiviral compositions containing bisbasic ethers and thioethers of xanthene and xanthen-9-ones and methods of treating viruses therewith - Google Patents
Antiviral compositions containing bisbasic ethers and thioethers of xanthene and xanthen-9-ones and methods of treating viruses therewithInfo
- Publication number
- GB1353536A GB1353536A GB3451271A GB3451271A GB1353536A GB 1353536 A GB1353536 A GB 1353536A GB 3451271 A GB3451271 A GB 3451271A GB 3451271 A GB3451271 A GB 3451271A GB 1353536 A GB1353536 A GB 1353536A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carbon atoms
- oxygen
- compound
- bisbasic
- xanthen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 title 1
- 241000700605 Viruses Species 0.000 title 1
- 150000002170 ethers Chemical class 0.000 title 1
- QDLAGTHXVHQKRE-UHFFFAOYSA-N lichenxanthone Natural products COC1=CC(O)=C2C(=O)C3=C(C)C=C(OC)C=C3OC2=C1 QDLAGTHXVHQKRE-UHFFFAOYSA-N 0.000 title 1
- 150000003568 thioethers Chemical class 0.000 title 1
- JNELGWHKGNBSMD-UHFFFAOYSA-N xanthone Chemical class C1=CC=C2C(=O)C3=CC=CC=C3OC2=C1 JNELGWHKGNBSMD-UHFFFAOYSA-N 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 3
- 239000001301 oxygen Substances 0.000 abstract 3
- 229910052760 oxygen Inorganic materials 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002911 monocyclic heterocycle group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- -1 pyrrolidino, piperidino, morpholino Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
- 150000003732 xanthenes Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D311/86—Oxygen atoms, e.g. xanthones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9697670A | 1970-12-10 | 1970-12-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1353536A true GB1353536A (en) | 1974-05-22 |
Family
ID=22260054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3451271A Expired GB1353536A (en) | 1970-12-10 | 1971-07-22 | Antiviral compositions containing bisbasic ethers and thioethers of xanthene and xanthen-9-ones and methods of treating viruses therewith |
Country Status (10)
| Country | Link |
|---|---|
| AU (1) | AU452736B2 (enrdf_load_stackoverflow) |
| BE (1) | BE776555A (enrdf_load_stackoverflow) |
| CA (1) | CA993795A (enrdf_load_stackoverflow) |
| DE (1) | DE2151720A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2118030B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1353536A (enrdf_load_stackoverflow) |
| IL (1) | IL37327A (enrdf_load_stackoverflow) |
| NL (1) | NL7112580A (enrdf_load_stackoverflow) |
| PH (1) | PH9405A (enrdf_load_stackoverflow) |
| ZA (1) | ZA714599B (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571666A (en) * | 1988-10-28 | 1996-11-05 | Oklahoma Medical Research Foundation | Thiazine dyes used to inactivate HIV in biological fluids |
| US11975106B2 (en) | 2020-03-26 | 2024-05-07 | Provectus Pharmatech, Inc. | Uses of halogenated xanthenes in oncology and virology |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3829440A (en) * | 1972-12-21 | 1974-08-13 | Richardson Merrell Inc | Xanthene derivatives |
| ZA738207B (en) * | 1972-12-21 | 1975-02-26 | Richardson Merrell Inc | Bis-basic ethers of 9-substituted phenanthrene and related 10-oxa and 10-aza derivatives therof |
| US3988335A (en) * | 1974-05-08 | 1976-10-26 | American Home Products Corporation | 1-Substituted-6-(2-substituted aminoethoxy)xanthen-9-ones |
| JPH07119173B2 (ja) * | 1989-05-11 | 1995-12-20 | オクラホマ メディカル リサーチ ファウンデーション | チアジン染料またはキサンテン染料を用いた薬剤組成物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1192651A (en) * | 1968-01-09 | 1970-05-20 | Sterling Drug Inc | Xanthene Derivatives |
| IL33573A (en) * | 1968-12-30 | 1973-10-25 | Richardson Merrell Inc | Bis-basic ethers and thioethers of fluorenone,fluorenol and fluorene |
-
1971
- 1971-07-05 CA CA117,341A patent/CA993795A/en not_active Expired
- 1971-07-13 ZA ZA714599A patent/ZA714599B/xx unknown
- 1971-07-16 IL IL37327A patent/IL37327A/xx unknown
- 1971-07-16 PH PH12645*UA patent/PH9405A/en unknown
- 1971-07-22 GB GB3451271A patent/GB1353536A/en not_active Expired
- 1971-07-30 AU AU31852/71A patent/AU452736B2/en not_active Expired
- 1971-09-13 NL NL7112580A patent/NL7112580A/xx not_active Application Discontinuation
- 1971-10-18 DE DE19712151720 patent/DE2151720A1/de not_active Withdrawn
- 1971-12-10 FR FR7144505A patent/FR2118030B1/fr not_active Expired
- 1971-12-10 BE BE776555A patent/BE776555A/xx unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571666A (en) * | 1988-10-28 | 1996-11-05 | Oklahoma Medical Research Foundation | Thiazine dyes used to inactivate HIV in biological fluids |
| US5827644A (en) * | 1988-10-28 | 1998-10-27 | Oklahoma Medical Research Foudation | Thiazine dyes used to inactivate HIV in biological fluids |
| US11975106B2 (en) | 2020-03-26 | 2024-05-07 | Provectus Pharmatech, Inc. | Uses of halogenated xanthenes in oncology and virology |
Also Published As
| Publication number | Publication date |
|---|---|
| AU452736B2 (en) | 1974-09-12 |
| AU3185271A (en) | 1973-02-01 |
| CA993795A (en) | 1976-07-27 |
| BE776555A (fr) | 1972-04-04 |
| PH9405A (en) | 1975-11-03 |
| DE2151720A1 (de) | 1972-06-29 |
| IL37327A0 (en) | 1971-10-20 |
| FR2118030B1 (enrdf_load_stackoverflow) | 1974-11-15 |
| NL7112580A (enrdf_load_stackoverflow) | 1972-06-13 |
| IL37327A (en) | 1974-09-10 |
| FR2118030A1 (enrdf_load_stackoverflow) | 1972-07-28 |
| ZA714599B (en) | 1972-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee | ||
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) |