GB1351501A - Adenosine derivatives and the production thereof - Google Patents
Adenosine derivatives and the production thereofInfo
- Publication number
- GB1351501A GB1351501A GB3012371A GB3012371A GB1351501A GB 1351501 A GB1351501 A GB 1351501A GB 3012371 A GB3012371 A GB 3012371A GB 3012371 A GB3012371 A GB 3012371A GB 1351501 A GB1351501 A GB 1351501A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compound
- june
- halogen
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003835 adenosine derivatives Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000000916 dilatatory effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5750770 | 1970-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1351501A true GB1351501A (en) | 1974-05-01 |
Family
ID=13057634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3012371A Expired GB1351501A (en) | 1970-06-30 | 1971-06-28 | Adenosine derivatives and the production thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3796700A (https=) |
| BE (1) | BE768925A (https=) |
| CA (1) | CA954856A (https=) |
| DE (1) | DE2131938A1 (https=) |
| FR (1) | FR2100839B1 (https=) |
| GB (1) | GB1351501A (https=) |
| HU (1) | HU163640B (https=) |
| NL (1) | NL7108858A (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5432164A (en) * | 1991-10-24 | 1995-07-11 | Novo Nordisk A/S | C2,N6 -disubstituted adenosine derivatives |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3922261A (en) * | 1972-06-21 | 1975-11-25 | Merck Patent Gmbh | Adenosine derivative |
| US5066655A (en) * | 1987-04-24 | 1991-11-19 | Whitby Research, Inc. | N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists |
| US5565566A (en) * | 1987-04-24 | 1996-10-15 | Discovery Therapeutics, Inc. | N6 -substituted 9-methyladenines: a new class of adenosine receptor antagonists |
| US5017578A (en) * | 1989-06-09 | 1991-05-21 | Hoechst-Roussel Pharmaceuticals Inc. | N-heteroaryl-purin-6-amines useful as analgesic and anticonvulsant agents |
| US5155098A (en) * | 1989-06-09 | 1992-10-13 | Hoechst-Roussel Pharmaceuticals Inc. | N-heteroaryl-purin-6-amines, and pharmaceutical compositions and methods employing them |
| AU654507B2 (en) * | 1990-09-25 | 1994-11-10 | Rhone-Poulenc Rorer International (Holdings) Inc. | Compounds having antihypertensive and anti-ischemic properties |
| US5561134A (en) * | 1990-09-25 | 1996-10-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
| USD337174S (en) | 1991-05-16 | 1993-07-06 | Sterling Roy J | Roll on suntain oil applicator |
| DK62592D0 (https=) * | 1992-05-14 | 1992-05-14 | Novo Nordisk As | |
| TW528755B (en) | 1996-12-24 | 2003-04-21 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
| YU44900A (sh) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
| JP3933870B2 (ja) | 1998-06-23 | 2007-06-20 | グラクソ グループ リミテッド | ２−（プリン−９−イル）−テトラヒドロフラン−３，４−ジオール誘導体 |
| US7205404B1 (en) | 1999-03-05 | 2007-04-17 | Metabasis Therapeutics, Inc. | Phosphorus-containing prodrugs |
| AU7361400A (en) * | 1999-09-08 | 2001-04-10 | Metabasis Therapeutics, Inc. | Prodrugs for liver specific drug delivery |
| PE20060272A1 (es) | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| AU2015217221A1 (en) | 2014-02-13 | 2016-08-11 | Ligand Pharmaceuticals, Inc. | Prodrug compounds and their uses |
| CN106687118A (zh) | 2014-07-02 | 2017-05-17 | 配体药物公司 | 前药化合物及其用途 |
| CA3087932A1 (en) | 2018-01-09 | 2019-07-18 | Ligand Pharmaceuticals, Inc. | Acetal compounds and therapeutic uses thereof |
-
1971
- 1971-06-23 US US00156138A patent/US3796700A/en not_active Expired - Lifetime
- 1971-06-23 BE BE768925A patent/BE768925A/xx unknown
- 1971-06-25 NL NL7108858A patent/NL7108858A/xx unknown
- 1971-06-26 DE DE19712131938 patent/DE2131938A1/de active Pending
- 1971-06-28 GB GB3012371A patent/GB1351501A/en not_active Expired
- 1971-06-29 FR FR7123583A patent/FR2100839B1/fr not_active Expired
- 1971-06-29 HU HUTA1126A patent/HU163640B/hu unknown
- 1971-06-30 CA CA117,084A patent/CA954856A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5432164A (en) * | 1991-10-24 | 1995-07-11 | Novo Nordisk A/S | C2,N6 -disubstituted adenosine derivatives |
| US5578582A (en) * | 1991-10-24 | 1996-11-26 | Novo Nordisk A/S | Methods of treating ischemia with C2, N6 -disubstituted adenosine derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| US3796700A (en) | 1974-03-12 |
| DE2131938A1 (de) | 1972-01-05 |
| HU163640B (https=) | 1973-09-27 |
| CA954856A (en) | 1974-09-17 |
| NL7108858A (https=) | 1972-01-03 |
| FR2100839A1 (https=) | 1972-03-24 |
| FR2100839B1 (https=) | 1974-09-06 |
| BE768925A (fr) | 1971-11-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1351501A (en) | Adenosine derivatives and the production thereof | |
| GB1505305A (en) | Benzcycloamide derivatives | |
| GB1260848A (en) | Propanolamine derivatives | |
| GB1436978A (en) | Choline derivatives and pharmaceutical compositions containing the same | |
| GB1367785A (en) | 2-substituted adenosine derivatives and the production thereof | |
| GB1236467A (en) | Benzothiazepine derivatives | |
| GB1439724A (en) | Berbine derivatives and pharmaceutical compositions containing them | |
| GB1358413A (en) | Sydnone imine derivatives and processes for preparing them | |
| GB1212454A (en) | N,n'-substituted formamidines | |
| GB1235599A (en) | Lincomycin phosphate derivatives and pharmaceutical compositions containing them | |
| GB1493684A (en) | S-substituted-2-thiodenosines | |
| GB1053843A (https=) | ||
| GB1336732A (en) | Diethanolamine derivatives | |
| GB1413454A (en) | 4-alkoxyalkyleneoxy-5-benzylpyrimidines their preparation and pharmaceutical compositions thereof | |
| GB1156781A (en) | New Heterocyclic Compounds | |
| GB1468079A (en) | Ethanolamine derivatives | |
| GB1469430A (en) | Daunomycin derivatives | |
| GB1263116A (en) | Chloramphenicol and thiamphenicol derivatives | |
| GB1272340A (en) | Derivatives of neriifolin | |
| GB1197691A (en) | Substituted Thienoimidazoles | |
| GB1415039A (en) | 6-aminouracil derivatives | |
| GB1139629A (en) | Cyclopentanone derivatives | |
| GB1339010A (en) | Tetrazolyl-anthraquinone derivatives | |
| GB1132397A (en) | Improvements in or relating to fluorene derivatives and the manufacture thereof | |
| GB1207629A (en) | Sydnone derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |