GB1344707A - Cephalosporins via penicillin sulphoxide conversion - Google Patents
Cephalosporins via penicillin sulphoxide conversionInfo
- Publication number
- GB1344707A GB1344707A GB2314671*A GB2314671A GB1344707A GB 1344707 A GB1344707 A GB 1344707A GB 2314671 A GB2314671 A GB 2314671A GB 1344707 A GB1344707 A GB 1344707A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compound
- cephalosporins
- pnitrobenzyl
- benzhydryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 3
- 229930182555 Penicillin Natural products 0.000 title abstract 3
- 229940124587 cephalosporin Drugs 0.000 title abstract 3
- 150000001780 cephalosporins Chemical class 0.000 title abstract 3
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 title abstract 2
- ATTZFSUZZUNHBP-UHFFFAOYSA-N Piperonyl sulfoxide Chemical compound CCCCCCCCS(=O)C(C)CC1=CC=C2OCOC2=C1 ATTZFSUZZUNHBP-UHFFFAOYSA-N 0.000 title abstract 2
- 238000006243 chemical reaction Methods 0.000 title abstract 2
- 229940049954 penicillin Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000004423 acyloxy group Chemical group 0.000 abstract 3
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical group C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 125000000453 2,2,2-trichloroethyl group Chemical group [H]C([H])(*)C(Cl)(Cl)Cl 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- -1 cephalosporanic acid ester Chemical class 0.000 abstract 2
- 239000012442 inert solvent Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- RBKMMJSQKNKNEV-RITPCOANSA-N penicillanic acid Chemical compound OC(=O)[C@H]1C(C)(C)S[C@@H]2CC(=O)N21 RBKMMJSQKNKNEV-RITPCOANSA-N 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 125000006000 trichloroethyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1692970A | 1970-03-05 | 1970-03-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1344707A true GB1344707A (en) | 1974-01-23 |
Family
ID=21779780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2314671*A Expired GB1344707A (en) | 1970-03-05 | 1971-04-19 | Cephalosporins via penicillin sulphoxide conversion |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3674775A (enExample) |
| BE (1) | BE763765A (enExample) |
| CH (1) | CH552624A (enExample) |
| DE (1) | DE2110660A1 (enExample) |
| ES (1) | ES388964A1 (enExample) |
| FR (2) | FR2094938A5 (enExample) |
| GB (1) | GB1344707A (enExample) |
| NL (1) | NL7103005A (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4123612A (en) * | 1970-08-10 | 1978-10-31 | Eli Lilly And Company | 7-(5-Amino-5-carboxyvaleramido)-3-(carbamoyoloxymethyl)-3-cephem-4-carboxylic acid |
| US4003894A (en) * | 1971-08-17 | 1977-01-18 | Gist-Brocades N.V. | Preparation of 7-substituted amino-desacetoxycephalosporanic acid compounds |
| US4145538A (en) * | 1976-05-06 | 1979-03-20 | Eli Lilly And Company | 3-Carbamyloxymethyl-cephalosporins |
-
1970
- 1970-03-05 US US16929A patent/US3674775A/en not_active Expired - Lifetime
-
1971
- 1971-02-22 CH CH252171A patent/CH552624A/xx not_active IP Right Cessation
- 1971-03-04 BE BE763765A patent/BE763765A/xx unknown
- 1971-03-05 NL NL7103005A patent/NL7103005A/xx unknown
- 1971-03-05 ES ES388964A patent/ES388964A1/es not_active Expired
- 1971-03-05 DE DE19712110660 patent/DE2110660A1/de active Pending
- 1971-03-05 FR FR7107749A patent/FR2094938A5/fr not_active Expired
- 1971-04-19 GB GB2314671*A patent/GB1344707A/en not_active Expired
- 1971-09-23 FR FR7134273A patent/FR2108465A5/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2110660A1 (de) | 1971-09-16 |
| FR2094938A5 (enExample) | 1972-02-04 |
| US3674775A (en) | 1972-07-04 |
| BE763765A (fr) | 1971-09-06 |
| ES388964A1 (es) | 1974-03-16 |
| FR2108465A5 (enExample) | 1972-05-19 |
| NL7103005A (enExample) | 1971-09-07 |
| CH552624A (de) | 1974-08-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IE37757B1 (en) | Penicillins and cephalosporins | |
| GB1470188A (en) | Penicillins | |
| IE43840L (en) | Clavulanic acid derivatives | |
| IE35438L (en) | 3-formyl cephalosporin sulphoxides | |
| GB1344707A (en) | Cephalosporins via penicillin sulphoxide conversion | |
| GB1367957A (en) | Process for preparing cephalosporins | |
| GB1454399A (en) | Alphaaminoacyl cephalosporin ethers | |
| IE35542L (en) | Method for preparing penicillin sulfoxides | |
| GB1377661A (en) | Oxofuryl ester derivatives of penicillin and cephalosporin | |
| GB1512660A (en) | Cephalosporin esters | |
| GB1467355A (en) | Preparation of 6-aminopenicillanic acid 7-aminocephalospo ranic acid and derivatives thereof | |
| GB1488308A (en) | Penicillin-type antibiotic and process for producing same | |
| IE32859B1 (en) | Penicilloic acid derivatives and process for the manufacture thereof | |
| GB1365954A (en) | Process for acetylation | |
| GB1377956A (en) | Antibacterial compounds | |
| GB1426557A (en) | Production of substituted monomalonate esters and their use in the production of alpha-carboxy penicillins and cephalosporins | |
| GB1204394A (en) | Process for converting a penicillin sulfoxide ester to a cephalosporin antibiotic | |
| ES457577A1 (es) | Un procedimiento de preparacion de nuevos compuestos de be- ta-lactama. | |
| GB1381160A (en) | Penicillin and cephalosporin c antibiotics the preparation thereof and pharmaceutical compositions containing them | |
| GB1388866A (en) | Amides of 6-isocyanatopenicillanic acid and 7-isocyanato cephalosporanic acid and methods for their preparation | |
| JPS5238092A (en) | Method of preparing 7-amino cephalosporanic acids | |
| ES2002912A6 (es) | Procedimiento para la produccion de antibioticos de cefalosporina | |
| GB1474545A (en) | Penicillin and cephalosporin cleavage process and compounds useful therein | |
| GB1458234A (en) | Penicillin and cephalosporin esters | |
| GB1430238A (en) | Esters |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |