GB1343834A - 4-3-alkyl-amino-2-pivaloyloxypropoxy-indole derivatives - Google Patents
4-3-alkyl-amino-2-pivaloyloxypropoxy-indole derivativesInfo
- Publication number
- GB1343834A GB1343834A GB2480871*A GB2480871A GB1343834A GB 1343834 A GB1343834 A GB 1343834A GB 2480871 A GB2480871 A GB 2480871A GB 1343834 A GB1343834 A GB 1343834A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- pivaloyloxypropoxy
- amino
- indole derivatives
- pivalic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000006645 (C3-C4) cycloalkyl group Chemical group 0.000 abstract 1
- PGZVFRAEAAXREB-UHFFFAOYSA-N 2,2-dimethylpropanoyl 2,2-dimethylpropanoate Chemical compound CC(C)(C)C(=O)OC(=O)C(C)(C)C PGZVFRAEAAXREB-UHFFFAOYSA-N 0.000 abstract 1
- NLMQHXUGJIAKTH-UHFFFAOYSA-N 4-hydroxyindole Chemical class OC1=CC=CC2=C1C=CN2 NLMQHXUGJIAKTH-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
- 102000012740 beta Adrenergic Receptors Human genes 0.000 abstract 1
- 108010079452 beta Adrenergic Receptors Proteins 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- IUGYQRQAERSCNH-UHFFFAOYSA-N pivalic acid Chemical compound CC(C)(C)C(O)=O IUGYQRQAERSCNH-UHFFFAOYSA-N 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/54—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/64—Oxygen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/12—Fertilization attaching inhibition
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH437970A CH532040A (de) | 1970-03-24 | 1970-03-24 | Verfahren zur Herstellung neuer Indolderivate |
| CH462070 | 1970-03-25 | ||
| US12310571A | 1971-03-10 | 1971-03-10 | |
| US00247083A US3829577A (en) | 1970-03-24 | 1972-04-24 | Methylenedioxy-phenoxy derivatives as agents for upsetting hormone balance in insects |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1343834A true GB1343834A (en) | 1974-01-16 |
Family
ID=27428770
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2480871*A Expired GB1343834A (en) | 1970-03-24 | 1971-04-19 | 4-3-alkyl-amino-2-pivaloyloxypropoxy-indole derivatives |
| GB25243/71A Expired GB1293312A (en) | 1970-03-24 | 1971-04-19 | Phenyl derivatives and a process for the manufacture thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB25243/71A Expired GB1293312A (en) | 1970-03-24 | 1971-04-19 | Phenyl derivatives and a process for the manufacture thereof |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US3686222A (enExample) |
| AT (2) | AT323152B (enExample) |
| BE (2) | BE763354A (enExample) |
| CA (1) | CA948207A (enExample) |
| CH (2) | CH532040A (enExample) |
| DE (2) | DE2113379A1 (enExample) |
| FR (2) | FR2085733B1 (enExample) |
| GB (2) | GB1343834A (enExample) |
| NL (2) | NL7102450A (enExample) |
| OA (1) | OA03699A (enExample) |
| SE (1) | SE370073B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0002792A1 (en) * | 1978-01-03 | 1979-07-11 | Sandoz Ag | 3-Aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3946040A (en) * | 1971-03-19 | 1976-03-23 | Hoffmann-La Roche Inc. | Propynyl benzyl ethers |
| US3962282A (en) * | 1971-10-08 | 1976-06-08 | Eli Lilly And Company | Juvenile hormone mimics |
| GB1419080A (en) * | 1972-12-29 | 1975-12-24 | Cheminova As | Chemical compounds having juvenile hormone activity |
| US3933837A (en) * | 1973-07-23 | 1976-01-20 | Sterling Drug Inc. | 3,4-Methylenedioxyphenoxy-alkyl diketones and keto-esters |
| US4246284A (en) * | 1973-07-23 | 1981-01-20 | Sterling Drug Inc. | Aminosulfonyl-substituted aryloxyalkyl diketones |
| US4182761A (en) * | 1973-07-23 | 1980-01-08 | Sterling Drug Inc. | Acyloxy-substituted aryloxyalkyl diketones |
| US4171376A (en) * | 1973-07-23 | 1979-10-16 | Sterling Drug Inc. | Aryloxyalkyl keto-esters |
| US4002615A (en) * | 1974-03-13 | 1977-01-11 | A/S Cheminova | Terpenoid compounds of substituted hydroxyalkyl-pyridines having juvenile hormone activity |
| ZA752736B (en) * | 1974-06-17 | 1976-04-28 | Hoffmann La Roche | Phenyl derivatives |
| US3968234A (en) * | 1975-03-05 | 1976-07-06 | The United States Of America As Represented By The Secretary Of Agriculture | Cinnamyl-sesamol derivatives as insect chemosterilants |
| DE2635209C2 (de) * | 1975-08-15 | 1983-01-27 | Sandoz-Patent-GmbH, 7850 Lörrach | 4-(2-Benzoyloxy-3-tert.butylamino-propoxy)-2-methylindol, dessen (S)-Enantiomeres, deren Säureadditionssalze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Heilmittel |
| US4206197A (en) * | 1975-11-26 | 1980-06-03 | The United States Of America As Represented By The Secretary Of The Navy | Chemical encapsulation and distribution |
| DE2905877A1 (de) * | 1979-02-16 | 1980-08-28 | Boehringer Mannheim Gmbh | Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US4788054A (en) * | 1986-07-11 | 1988-11-29 | Stepan Company | N-phenylphthalisomides as ultraviolet radiation absorbers |
| JP4456334B2 (ja) * | 2003-02-14 | 2010-04-28 | 高砂香料工業株式会社 | メラニン生成抑制剤及びそれを含有する皮膚外用剤 |
-
1970
- 1970-03-24 CH CH437970A patent/CH532040A/de not_active IP Right Cessation
- 1970-03-25 CH CH462070A patent/CH542580A/de not_active IP Right Cessation
-
1971
- 1971-02-24 BE BE763354A patent/BE763354A/xx unknown
- 1971-02-24 NL NL7102450A patent/NL7102450A/xx unknown
- 1971-03-10 US US123105A patent/US3686222A/en not_active Expired - Lifetime
- 1971-03-19 DE DE19712113379 patent/DE2113379A1/de active Pending
- 1971-03-22 BE BE764660A patent/BE764660A/xx unknown
- 1971-03-22 CA CA108,321A patent/CA948207A/en not_active Expired
- 1971-03-22 FR FR7109963A patent/FR2085733B1/fr not_active Expired
- 1971-03-23 SE SE03739/71A patent/SE370073B/xx unknown
- 1971-03-23 AT AT959772A patent/AT323152B/de not_active IP Right Cessation
- 1971-03-23 FR FR7110148A patent/FR2093422A5/fr not_active Expired
- 1971-03-23 AT AT249571A patent/AT317885B/de not_active IP Right Cessation
- 1971-03-23 NL NL7103858A patent/NL7103858A/xx not_active Application Discontinuation
- 1971-03-23 OA OA54210A patent/OA03699A/xx unknown
- 1971-03-24 DE DE19712114228 patent/DE2114228A1/de active Pending
- 1971-04-19 GB GB2480871*A patent/GB1343834A/en not_active Expired
- 1971-04-19 GB GB25243/71A patent/GB1293312A/en not_active Expired
-
1972
- 1972-04-24 US US00247083A patent/US3829577A/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0002792A1 (en) * | 1978-01-03 | 1979-07-11 | Sandoz Ag | 3-Aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them |
Also Published As
| Publication number | Publication date |
|---|---|
| OA03699A (fr) | 1971-12-24 |
| BE764660A (fr) | 1971-09-22 |
| US3686222A (en) | 1972-08-22 |
| CH542580A (de) | 1973-11-30 |
| CH532040A (de) | 1972-12-31 |
| NL7102450A (enExample) | 1971-09-28 |
| AT323152B (de) | 1975-06-25 |
| FR2093422A5 (enExample) | 1972-01-28 |
| FR2085733B1 (enExample) | 1974-05-24 |
| US3829577A (en) | 1974-08-13 |
| GB1293312A (en) | 1972-10-18 |
| AT317885B (de) | 1974-09-25 |
| DE2113379A1 (de) | 1971-10-07 |
| BE763354A (fr) | 1971-08-24 |
| FR2085733A1 (enExample) | 1971-12-31 |
| NL7103858A (enExample) | 1971-09-28 |
| DE2114228A1 (de) | 1971-10-14 |
| CA948207A (en) | 1974-05-28 |
| SE370073B (enExample) | 1974-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |