GB1330360A - Cardiac steroid talomethylosides - Google Patents
Cardiac steroid talomethylosidesInfo
- Publication number
- GB1330360A GB1330360A GB5093971A GB5093971A GB1330360A GB 1330360 A GB1330360 A GB 1330360A GB 5093971 A GB5093971 A GB 5093971A GB 5093971 A GB5093971 A GB 5093971A GB 1330360 A GB1330360 A GB 1330360A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- formula
- cho
- group
- together represent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003431 steroids Chemical class 0.000 title abstract 2
- 230000000747 cardiac effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 9
- OISVCGZHLKNMSJ-UHFFFAOYSA-N 2,6-dimethylpyridine Chemical compound CC1=CC=CC(C)=N1 OISVCGZHLKNMSJ-UHFFFAOYSA-N 0.000 abstract 3
- 229910052799 carbon Inorganic materials 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000001589 carboacyl group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- XWKFPIODWVPXLX-UHFFFAOYSA-N 2-methyl-5-methylpyridine Natural products CC1=CC=C(C)N=C1 XWKFPIODWVPXLX-UHFFFAOYSA-N 0.000 abstract 1
- HAJGVUYNXHQLER-UHFFFAOYSA-N Bufadienolide Natural products O1C(=O)C=CC(C2C3C(C4C(C5CCCCC5CC4)CC3)CC2)=C1 HAJGVUYNXHQLER-UHFFFAOYSA-N 0.000 abstract 1
- TYYDXNISHGVDGA-UHFFFAOYSA-N Corotoxigenin Natural products CC12CCC3C(CCC4CC(O)CCC34C=O)C1CCC2C5=CC(=O)OC5 TYYDXNISHGVDGA-UHFFFAOYSA-N 0.000 abstract 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
- 238000006359 acetalization reaction Methods 0.000 abstract 1
- 150000001241 acetals Chemical class 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- -1 heterocyclic carboxylic acid Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000005907 ketalization reaction Methods 0.000 abstract 1
- 229910052987 metal hydride Inorganic materials 0.000 abstract 1
- 150000004681 metal hydrides Chemical class 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052709 silver Inorganic materials 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702053682 DE2053682A1 (en) | 1970-11-02 | 1970-11-02 | Cardiotonic alpha-l-talomethylosides - having better absorption |
| DE19712147998 DE2147998A1 (de) | 1971-09-25 | 1971-09-25 | Neues verfahren zur herstellung von alpha-l-talomethylosiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1330360A true GB1330360A (en) | 1973-09-19 |
Family
ID=25760011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5093971A Expired GB1330360A (en) | 1970-11-02 | 1971-11-02 | Cardiac steroid talomethylosides |
Country Status (9)
| Country | Link |
|---|---|
| BE (1) | BE774871A (enExample) |
| CA (1) | CA936525A (enExample) |
| DK (1) | DK127476B (enExample) |
| FI (1) | FI48829C (enExample) |
| FR (1) | FR2112406B1 (enExample) |
| GB (1) | GB1330360A (enExample) |
| HU (1) | HU163058B (enExample) |
| IL (1) | IL38051A0 (enExample) |
| NL (1) | NL7115088A (enExample) |
-
1971
- 1971-10-22 FI FI712998A patent/FI48829C/fi active
- 1971-11-01 CA CA126548A patent/CA936525A/en not_active Expired
- 1971-11-01 IL IL38051A patent/IL38051A0/xx unknown
- 1971-11-01 HU HUTO861A patent/HU163058B/hu unknown
- 1971-11-01 DK DK534071AA patent/DK127476B/da unknown
- 1971-11-02 FR FR7139283A patent/FR2112406B1/fr not_active Expired
- 1971-11-02 GB GB5093971A patent/GB1330360A/en not_active Expired
- 1971-11-02 NL NL7115088A patent/NL7115088A/xx unknown
- 1971-11-03 BE BE774871A patent/BE774871A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU163058B (enExample) | 1973-05-28 |
| BE774871A (fr) | 1972-05-03 |
| FR2112406A1 (enExample) | 1972-06-16 |
| FI48829C (fi) | 1975-01-10 |
| IL38051A0 (en) | 1972-01-27 |
| CA936525A (en) | 1973-11-06 |
| FI48829B (enExample) | 1974-09-30 |
| NL7115088A (enExample) | 1972-05-04 |
| FR2112406B1 (enExample) | 1975-12-26 |
| DK127476B (da) | 1973-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |