GB1326961A - Alkanolymine derivatives - Google Patents

Abstract

1326961 Alkanolamine derivatives IMPERIAL CHEMICAL INDUSTRIES Ltd 21 May 1971 [27 May 1970 20 Nov 1970] 25529/70 and 55246/70 Heading C2C [Also in Division A5] Compounds of the general formula (R<SP>1</SP> = H, cycloalkyl, alkenyl, alkyl optionally substituted by hydroxy, aryl and/or aryloxy; R<SP>2</SP> = H, alkyl; R<SP>3</SP> = H, alkyl, hydroxyalkyl, alkoxyalkyl, cycloalkyl, alkenyl, aralkyl or NR<SP>2</SP>R<SP>3</SP> = heterocyclic group; R<SP>4</SP> = H, halogen, alkyl, alkenyl, OH, alkylthio, alkoxy, alkenyloxy, aralkoxy, haloalkyl; R<SP>5</SP> = H, alkyl; A = alkylene) and their esters and aldehyde condensation products, and acid addition salts thereof are prepared by standard methods. The preparation of 3-allyl-4-hydroxyphenoxyacetic acid, 3 - allyl - 4 - hydroxyphenoxyacetamide, p - hydroxyphenoxy - N - methylacetamide, 4 - benzyloxy - 3 - methoxyphenoxyacetic acid, 4 - hydroxy - 3 - methoxyphenoxyacetic acid, 4 - hydroxy - 3 - methoxyphenoxyacetamide, phenols of the formula 5 - bromo - 2 - hydroxyphenoxyacetic acid, 6- bromo - 1,4 - benzodioxan - 2 - one, 5 - bromo - 2- hydroxyphenoxy - N - methylacetamide, 5 - benzyloxy - 2 - hydroxy - N - methylphenoxyacetamide, 2 - hydroxy - N,5 - dimethylphenoxyacetamide, 2 - hydroxy - 5 - methoxy - N - methylphenoxyacetamide, m - hydroxyphenoxy - N - methylacetamide, 3 - p - hydroxyphenoxybutyramide, 3 - bromo - 4 - hydroxyphenoxyacetic acid, methyl 3 - bromo - 4 - hydroxyphenoxyacetate, 3 - bromo - 4 - hydroxyphenoxyaoetamide, 4- hydroxy - 3 - methylphenoxyacetamide and 1 - (4- ethoxycarbonylmethoxyphenoxy)- 3 - isopropylaminopropan-2-ol is described.