GB1313990A - Process for the preparation of cephalexin - Google Patents
Process for the preparation of cephalexinInfo
- Publication number
- GB1313990A GB1313990A GB1353772A GB1353772A GB1313990A GB 1313990 A GB1313990 A GB 1313990A GB 1353772 A GB1353772 A GB 1353772A GB 1353772 A GB1353772 A GB 1353772A GB 1313990 A GB1313990 A GB 1313990A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cephalexin
- preparation
- derivative
- march
- reacted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZAIPMKNFIOOWCQ-UEKVPHQBSA-N cephalexin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C)C(O)=O)=CC=CC=C1 ZAIPMKNFIOOWCQ-UEKVPHQBSA-N 0.000 title abstract 3
- 229940106164 cephalexin Drugs 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 229930186147 Cephalosporin Natural products 0.000 abstract 2
- 229940124587 cephalosporin Drugs 0.000 abstract 2
- 150000001780 cephalosporins Chemical class 0.000 abstract 2
- -1 phenylacetyl Chemical group 0.000 abstract 2
- 150000005331 phenylglycines Chemical class 0.000 abstract 2
- 241000194107 Bacillus megaterium Species 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000001980 alanyl group Chemical group 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- QUPDWYMUPZLYJZ-UHFFFAOYSA-N ethyl Chemical group C[CH2] QUPDWYMUPZLYJZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000001998 leucyl group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/04—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP46016886A JPS5220552B1 (enExample) | 1971-03-25 | 1971-03-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1313990A true GB1313990A (en) | 1973-04-18 |
Family
ID=11928638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1353772A Expired GB1313990A (en) | 1971-03-25 | 1972-03-23 | Process for the preparation of cephalexin |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5220552B1 (enExample) |
| AT (1) | AT313473B (enExample) |
| BE (1) | BE781205A (enExample) |
| CA (1) | CA986439A (enExample) |
| CH (1) | CH576477A5 (enExample) |
| CS (1) | CS157140B2 (enExample) |
| DD (1) | DD97214A5 (enExample) |
| DE (1) | DE2214444A1 (enExample) |
| FR (1) | FR2130586B1 (enExample) |
| GB (1) | GB1313990A (enExample) |
| HU (1) | HU165268B (enExample) |
| NL (1) | NL7203989A (enExample) |
| PL (1) | PL83297B1 (enExample) |
| SE (1) | SE393113B (enExample) |
-
1971
- 1971-03-25 JP JP46016886A patent/JPS5220552B1/ja active Pending
-
1972
- 1972-03-21 HU HUTO000868 patent/HU165268B/hu unknown
- 1972-03-22 SE SE365272A patent/SE393113B/xx unknown
- 1972-03-23 FR FR7210172A patent/FR2130586B1/fr not_active Expired
- 1972-03-23 GB GB1353772A patent/GB1313990A/en not_active Expired
- 1972-03-23 CS CS194172A patent/CS157140B2/cs unknown
- 1972-03-23 PL PL15424572A patent/PL83297B1/xx unknown
- 1972-03-24 DD DD16190672A patent/DD97214A5/xx unknown
- 1972-03-24 NL NL7203989A patent/NL7203989A/xx unknown
- 1972-03-24 DE DE19722214444 patent/DE2214444A1/de active Pending
- 1972-03-24 CA CA138,007A patent/CA986439A/en not_active Expired
- 1972-03-24 BE BE781205A patent/BE781205A/xx unknown
- 1972-03-24 CH CH443772A patent/CH576477A5/xx not_active IP Right Cessation
- 1972-03-27 AT AT263072A patent/AT313473B/de active
Also Published As
| Publication number | Publication date |
|---|---|
| DE2214444A1 (enExample) | 1972-11-09 |
| CH576477A5 (enExample) | 1976-06-15 |
| AT313473B (de) | 1974-02-25 |
| JPS5220552B1 (enExample) | 1977-06-04 |
| NL7203989A (enExample) | 1972-09-27 |
| PL83297B1 (enExample) | 1975-12-31 |
| HU165268B (enExample) | 1974-07-27 |
| DD97214A5 (enExample) | 1973-04-20 |
| FR2130586A1 (enExample) | 1972-11-03 |
| CS157140B2 (enExample) | 1974-08-23 |
| FR2130586B1 (enExample) | 1976-06-11 |
| BE781205A (fr) | 1972-07-17 |
| CA986439A (en) | 1976-03-30 |
| SE393113B (sv) | 1977-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |