GB1302322A - - Google Patents
Info
- Publication number
- GB1302322A GB1302322A GB1329671*[A GB1329671A GB1302322A GB 1302322 A GB1302322 A GB 1302322A GB 1329671 A GB1329671 A GB 1329671A GB 1302322 A GB1302322 A GB 1302322A
- Authority
- GB
- United Kingdom
- Prior art keywords
- inorganic salt
- salt content
- venom
- solutions
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
- C12N9/6418—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals from snakes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
1302322 Anti-coagulant isolation ABBOTT LABORATORIES 5 May 1971 [1 June 1970] 13296/71 Heading ASB Biologically pure solutions of the thrombinlike material obtained from pit viper venom having anticoagulant activity are prepared by placing an aqueous solution containing 5-20% weight/volume of native venom buffered to a pH of 7.0 Π1.0 and containing from 0.15 to 0.5 molarity of total inorganic salt content on a column packed with a molecular sieve such as a partially cross-linked dextran gel or a polyacrylamide gel, eluting said column with an aqueous solution containing the same type and amount of inorganic salt content as the venom solution in small fractions and pooling the fractions which contain thrombin-like activity. The inorganic salt content preferably comprises equal molar proportions of sodium chloride and sodium phosphate. Injectable solutions are prepared from the above obtained solutions of the thrombin-like material.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4259670A | 1970-06-01 | 1970-06-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1302322A true GB1302322A (en) | 1973-01-10 |
Family
ID=21922772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1329671*[A Expired GB1302322A (en) | 1970-06-01 | 1971-05-05 |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS5414163B1 (en) |
| CA (1) | CA953212A (en) |
| DE (1) | DE2126713A1 (en) |
| FR (1) | FR2104751B1 (en) |
| GB (1) | GB1302322A (en) |
| ZA (1) | ZA712888B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101797377B (en) * | 2009-02-11 | 2012-01-25 | 北京赛升药业股份有限公司 | Fibrin sealant and preparation method thereof |
-
1971
- 1971-05-03 CA CA111,984A patent/CA953212A/en not_active Expired
- 1971-05-04 ZA ZA712888A patent/ZA712888B/en unknown
- 1971-05-05 GB GB1329671*[A patent/GB1302322A/en not_active Expired
- 1971-05-24 JP JP3483071A patent/JPS5414163B1/ja active Pending
- 1971-05-27 FR FR7119348A patent/FR2104751B1/fr not_active Expired
- 1971-05-28 DE DE19712126713 patent/DE2126713A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2104751A1 (en) | 1972-04-21 |
| DE2126713A1 (en) | 1971-12-09 |
| FR2104751B1 (en) | 1975-10-31 |
| CA953212A (en) | 1974-08-20 |
| JPS5414163B1 (en) | 1979-06-05 |
| ZA712888B (en) | 1972-01-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |