GB1298157A - BENZO-(b)-THIOPHENE DERIVATIVES AND COMPOSITIONS CONTAINING THE SAME - Google Patents
BENZO-(b)-THIOPHENE DERIVATIVES AND COMPOSITIONS CONTAINING THE SAMEInfo
- Publication number
- GB1298157A GB1298157A GB1097370A GB1097370A GB1298157A GB 1298157 A GB1298157 A GB 1298157A GB 1097370 A GB1097370 A GB 1097370A GB 1097370 A GB1097370 A GB 1097370A GB 1298157 A GB1298157 A GB 1298157A
- Authority
- GB
- United Kingdom
- Prior art keywords
- thiophene
- tetrahydrobenzo
- carbamoyl
- benzo
- thiophene derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004802 benzothiophens Chemical class 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 2
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
- SNDSZMXCBPPOQO-UHFFFAOYSA-N 2-(3-bromopropanoylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide Chemical compound BrCCC(=O)NC1=C(C2=C(S1)CCCC2)C(N)=O SNDSZMXCBPPOQO-UHFFFAOYSA-N 0.000 abstract 1
- XRKRPMKJSPGFRD-UHFFFAOYSA-N 2-[(2-chloroacetyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide Chemical compound C1CCCC2=C1SC(NC(=O)CCl)=C2C(=O)N XRKRPMKJSPGFRD-UHFFFAOYSA-N 0.000 abstract 1
- FFAKFORHXDNYEN-UHFFFAOYSA-N 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide Chemical compound C1CCCC2=C1SC(N)=C2C(=O)N FFAKFORHXDNYEN-UHFFFAOYSA-N 0.000 abstract 1
- FRXLFVNGTPQFEJ-UHFFFAOYSA-N 3-bromopropanoyl bromide Chemical compound BrCCC(Br)=O FRXLFVNGTPQFEJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002853 C1-C4 hydroxyalkyl group Chemical group 0.000 abstract 1
- VGCXGMAHQTYDJK-UHFFFAOYSA-N Chloroacetyl chloride Chemical compound ClCC(Cl)=O VGCXGMAHQTYDJK-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229960005015 local anesthetics Drugs 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR6906389A FR2035767A1 (enExample) | 1969-03-07 | 1969-03-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1298157A true GB1298157A (en) | 1972-11-29 |
Family
ID=9030273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1097370A Expired GB1298157A (en) | 1969-03-07 | 1970-03-06 | BENZO-(b)-THIOPHENE DERIVATIVES AND COMPOSITIONS CONTAINING THE SAME |
Country Status (2)
| Country | Link |
|---|---|
| FR (1) | FR2035767A1 (enExample) |
| GB (1) | GB1298157A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2128234A1 (en) * | 1971-03-12 | 1972-10-20 | Centre Etd Ind Pharma | Compsns contg 2-amino-4,5,6,7-tetrahydrobenzo (b) thiophen - -3-carboxamide - with analgesic,sedative,antitussive and diuretic act |
| CA1094063A (en) * | 1977-08-22 | 1981-01-20 | Davis L. Temple, Jr. | Thieno ¬2,3-d| pyrimidine antiallergic agents |
-
1969
- 1969-03-07 FR FR6906389A patent/FR2035767A1/fr not_active Withdrawn
-
1970
- 1970-03-06 GB GB1097370A patent/GB1298157A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2035767A1 (enExample) | 1970-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |