GB1295539A - - Google Patents
Info
- Publication number
- GB1295539A GB1295539A GB1295539DA GB1295539A GB 1295539 A GB1295539 A GB 1295539A GB 1295539D A GB1295539D A GB 1295539DA GB 1295539 A GB1295539 A GB 1295539A
- Authority
- GB
- United Kingdom
- Prior art keywords
- viquidil
- salt
- ptoluyl
- salts
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- DKRSEIPLAZTSFD-LSDHHAIUSA-N viquidil Chemical class C12=CC(OC)=CC=C2N=CC=C1C(=O)CC[C@@H]1CCNC[C@@H]1C=C DKRSEIPLAZTSFD-LSDHHAIUSA-N 0.000 abstract 6
- DKRSEIPLAZTSFD-UHFFFAOYSA-N d-quinotoxine Natural products C12=CC(OC)=CC=C2N=CC=C1C(=O)CCC1CCNCC1C=C DKRSEIPLAZTSFD-UHFFFAOYSA-N 0.000 abstract 4
- 229960003353 viquidil Drugs 0.000 abstract 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical group OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 abstract 2
- LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 abstract 2
- LOUPRKONTZGTKE-LHHVKLHASA-N quinidine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@H]2[C@@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-LHHVKLHASA-N 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- NSFIAKFOCAEBER-QZTJIDSGSA-N (2s,3s)-2,3-dihydroxy-2,3-bis(4-methylphenyl)butanedioic acid Chemical class C1=CC(C)=CC=C1[C@@](O)(C(O)=O)[C@](O)(C(O)=O)C1=CC=C(C)C=C1 NSFIAKFOCAEBER-QZTJIDSGSA-N 0.000 abstract 1
- 235000001258 Cinchona calisaya Nutrition 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 229960001270 d- tartaric acid Drugs 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 238000006317 isomerization reaction Methods 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 229960001404 quinidine Drugs 0.000 abstract 1
- 229960000948 quinine Drugs 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000007142 ring opening reaction Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2183070 | 1970-05-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1295539A true GB1295539A (enrdf_load_stackoverflow) | 1972-11-08 |
Family
ID=10169528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1295539D Expired GB1295539A (enrdf_load_stackoverflow) | 1970-05-06 | 1970-05-06 |
Country Status (4)
| Country | Link |
|---|---|
| DE (1) | DE2122056A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2078358A5 (enrdf_load_stackoverflow) |
| GB (1) | GB1295539A (enrdf_load_stackoverflow) |
| NL (1) | NL7102930A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0030044A1 (en) * | 1979-11-01 | 1981-06-10 | Acf Chemiefarma Nv | Quinoline derivatives, processes for their preparation, their use, pharmaceutical compositions containing them and a method for the preparation of these pharmaceutical compositions |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5846903B2 (ja) * | 1975-06-03 | 1983-10-19 | ソニー株式会社 | スイヘイシユツリヨクカイロノイジヨウケンシユツカイロ |
-
1970
- 1970-05-06 GB GB1295539D patent/GB1295539A/en not_active Expired
-
1971
- 1971-02-09 FR FR7104217A patent/FR2078358A5/fr not_active Expired
- 1971-03-05 NL NL7102930A patent/NL7102930A/xx unknown
- 1971-05-04 DE DE19712122056 patent/DE2122056A1/de active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0030044A1 (en) * | 1979-11-01 | 1981-06-10 | Acf Chemiefarma Nv | Quinoline derivatives, processes for their preparation, their use, pharmaceutical compositions containing them and a method for the preparation of these pharmaceutical compositions |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7102930A (enrdf_load_stackoverflow) | 1971-11-09 |
| DE2122056A1 (de) | 1971-12-23 |
| FR2078358A5 (enrdf_load_stackoverflow) | 1971-11-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
| PE20 | Patent expired after termination of 20 years |