GB1293694A - Substituted pyrrolemethylamines and their preparation - Google Patents
Substituted pyrrolemethylamines and their preparationInfo
- Publication number
- GB1293694A GB1293694A GB04845/71A GB1484571A GB1293694A GB 1293694 A GB1293694 A GB 1293694A GB 04845/71 A GB04845/71 A GB 04845/71A GB 1484571 A GB1484571 A GB 1484571A GB 1293694 A GB1293694 A GB 1293694A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- substituted
- amine
- trisubstituted
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YXMWGHKZTMANIJ-UHFFFAOYSA-N 1h-pyrrol-2-ylmethanamine Chemical class NCC1=CC=CN1 YXMWGHKZTMANIJ-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000006705 (C5-C7) cycloalkyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- ZSKGQVFRTSEPJT-UHFFFAOYSA-N pyrrole-2-carboxaldehyde Chemical class O=CC1=CC=CN1 ZSKGQVFRTSEPJT-UHFFFAOYSA-N 0.000 abstract 2
- -1 α- methylbenzyl Chemical group 0.000 abstract 2
- KAESVJOAVNADME-UHFFFAOYSA-N 1H-pyrrole Natural products C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 1
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001721 carbon Chemical group 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 150000002466 imines Chemical class 0.000 abstract 1
- 125000006384 methylpyridyl group Chemical group 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 150000003141 primary amines Chemical class 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003233 pyrroles Chemical class 0.000 abstract 1
- 125000005493 quinolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000467 secondary amino group Chemical class [H]N([*:1])[*:2] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3731370A | 1970-05-14 | 1970-05-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1293694A true GB1293694A (en) | 1972-10-18 |
Family
ID=21893671
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB04845/71A Expired GB1293694A (en) | 1970-05-14 | 1971-05-13 | Substituted pyrrolemethylamines and their preparation |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3721673A (enExample) |
| BE (1) | BE767202A (enExample) |
| DE (1) | DE2123468A1 (enExample) |
| FR (1) | FR2100659B1 (enExample) |
| GB (1) | GB1293694A (enExample) |
| IL (2) | IL36728A0 (enExample) |
| NL (1) | NL7106690A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0115042A (pt) * | 2000-10-30 | 2004-02-03 | Warner Lambert Co | Ligandos de receptores de aminoalquilpirrolidina serotonina e composições, seus usos farmacêuticos, e processos para a sua sìntese |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2951078A (en) * | 1957-08-21 | 1960-08-30 | Lakeside Lab Inc | 2-(aminoalkylamino)-methylpyrrolidines |
-
1970
- 1970-04-27 IL IL36728A patent/IL36728A0/xx unknown
- 1970-05-14 US US00037313A patent/US3721673A/en not_active Expired - Lifetime
-
1971
- 1971-04-27 IL IL36728A patent/IL36728A/xx unknown
- 1971-05-12 DE DE19712123468 patent/DE2123468A1/de active Pending
- 1971-05-13 GB GB04845/71A patent/GB1293694A/en not_active Expired
- 1971-05-14 BE BE767202A patent/BE767202A/xx unknown
- 1971-05-14 NL NL7106690A patent/NL7106690A/xx unknown
- 1971-05-14 FR FR7117609A patent/FR2100659B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2123468A1 (de) | 1971-11-25 |
| FR2100659A1 (enExample) | 1972-03-24 |
| NL7106690A (enExample) | 1971-11-16 |
| US3721673A (en) | 1973-03-20 |
| BE767202A (fr) | 1971-10-01 |
| IL36728A0 (en) | 1971-06-23 |
| IL36728A (en) | 1973-06-29 |
| FR2100659B1 (enExample) | 1974-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |