GB1290203A - - Google Patents

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Publication number
GB1290203A
GB1290203A GB1290203DA GB1290203A GB 1290203 A GB1290203 A GB 1290203A GB 1290203D A GB1290203D A GB 1290203DA GB 1290203 A GB1290203 A GB 1290203A
Authority
GB
United Kingdom
Prior art keywords
alkylation
esterification
acid derivatives
lysergic
monohydroxycycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GB1290203A publication Critical patent/GB1290203A/en
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1290203 Lysergic acid esters ELI LILLY & CO 1 Sept 1970 41711/70 Heading C2C Novel compounds I and II in which R<SP>1</SP> is H, 1-3C alkyl, allyl or benzyl and R<SP>2</SP> is 2-8C mono- or di-hydroxyalkyl or 5-11C monohydroxycycloalkyl in which there are 5-8 ring C and their salts are prepared by esterification of the free acid and/or alkylation of the N atom in the 4-position. The lysergic acid derivatives may be hydrogenated to the dihydrolysergic acid derivatives prior to or after the alkylation and/or esterification.
GB1290203D 1970-09-01 1970-09-01 Expired GB1290203A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4171170 1970-09-01

Publications (1)

Publication Number Publication Date
GB1290203A true GB1290203A (en) 1972-09-20

Family

ID=10421007

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1290203D Expired GB1290203A (en) 1970-09-01 1970-09-01

Country Status (1)

Country Link
GB (1) GB1290203A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4563461A (en) * 1983-03-10 1986-01-07 Eli Lilly And Company Selective method for blocking 5HT2 receptors
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4563461A (en) * 1983-03-10 1986-01-07 Eli Lilly And Company Selective method for blocking 5HT2 receptors
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees
PCNP Patent ceased through non-payment of renewal fee