GB1274307A - Process for producing aminobenzophenone derivatives and their salts - Google Patents
Process for producing aminobenzophenone derivatives and their saltsInfo
- Publication number
- GB1274307A GB1274307A GB28860/69A GB2886069A GB1274307A GB 1274307 A GB1274307 A GB 1274307A GB 28860/69 A GB28860/69 A GB 28860/69A GB 2886069 A GB2886069 A GB 2886069A GB 1274307 A GB1274307 A GB 1274307A
- Authority
- GB
- United Kingdom
- Prior art keywords
- salts
- formula
- producing
- carbalkoxycarbonyl
- cho
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 4
- MAOBFOXLCJIFLV-UHFFFAOYSA-N (2-aminophenyl)-phenylmethanone Chemical class NC1=CC=CC=C1C(=O)C1=CC=CC=C1 MAOBFOXLCJIFLV-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- FBOUIAKEJMZPQG-AWNIVKPZSA-N (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol Chemical compound C1=NC=NN1/C(C(O)C(C)(C)C)=C/C1=CC=C(Cl)C=C1Cl FBOUIAKEJMZPQG-AWNIVKPZSA-N 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000003431 oxalo group Chemical group 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
- C07C227/20—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters by hydrolysis of N-acylated amino-acids or derivatives thereof, e.g. hydrolysis of carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/22—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1,274,307. Aminobenzophenones. SUMI. TOMO CHEMICAL CO. Ltd. 6 June, 1969 [13 June, 1968 (2); 12 July, 1968; 19 Aug., 1968], No. 28860/69. Heading C2C. Compounds of the general formula (X, Y=H, halogen; R=C 1-3 alkyl; R 1 =H, C 1-3 alkyl) and their salts are prepared by contacting a compound of the formula (R 2 =CHO, carbalkoxycarbonyl) or salt thereof at an elevated temperature with a hydrolysing agent under alkaline conditions, optionally followed by alkylation and/or salt formation. The starting materials are prepared by alkylating a compound of the formula (R 3 =CHO, carboxycarbonyl, carbalkoxycarbonyl). Reference has been directed by the Comptroller to Specification 1,148,622.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4110468 | 1968-06-13 | ||
| JP4110368 | 1968-06-13 | ||
| JP4934968A JPS4823080B1 (en) | 1968-07-12 | 1968-07-12 | |
| JP5935968 | 1968-08-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1274307A true GB1274307A (en) | 1972-05-17 |
Family
ID=27460997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB28860/69A Expired GB1274307A (en) | 1968-06-13 | 1969-06-06 | Process for producing aminobenzophenone derivatives and their salts |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE734473A (en) |
| CH (1) | CH537901A (en) |
| DE (1) | DE1929138C3 (en) |
| FR (1) | FR2010835A1 (en) |
| GB (1) | GB1274307A (en) |
| NL (1) | NL6908956A (en) |
| SE (1) | SE365504B (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3431304A (en) * | 1965-09-22 | 1969-03-04 | Hoffmann La Roche | 2 - aminoalkylamino-benzophenones-oximes and imines and the salts thereof |
-
1969
- 1969-06-06 GB GB28860/69A patent/GB1274307A/en not_active Expired
- 1969-06-09 DE DE1929138A patent/DE1929138C3/en not_active Expired
- 1969-06-12 SE SE08376/69A patent/SE365504B/xx unknown
- 1969-06-12 NL NL6908956A patent/NL6908956A/xx unknown
- 1969-06-12 CH CH900569A patent/CH537901A/en not_active IP Right Cessation
- 1969-06-12 BE BE734473D patent/BE734473A/xx unknown
- 1969-06-13 FR FR6919719A patent/FR2010835A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| FR2010835A1 (en) | 1970-02-20 |
| DE1929138B2 (en) | 1973-06-07 |
| DE1929138C3 (en) | 1974-01-17 |
| SE365504B (en) | 1974-03-25 |
| BE734473A (en) | 1969-11-17 |
| CH537901A (en) | 1973-06-15 |
| NL6908956A (en) | 1969-12-16 |
| DE1929138A1 (en) | 1969-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |