GB1265536A - - Google Patents
Info
- Publication number
- GB1265536A GB1265536A GB1265536DA GB1265536A GB 1265536 A GB1265536 A GB 1265536A GB 1265536D A GB1265536D A GB 1265536DA GB 1265536 A GB1265536 A GB 1265536A
- Authority
- GB
- United Kingdom
- Prior art keywords
- salt
- compositions
- pharmaceutically acceptable
- pyrimidine derivative
- sulphanilamidoisoxazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,265,536. Anti-protozoal composition. TAKEDA YAKUHIN KOGYO K.K. 6 May, 1969 [6 May, 1968], No. 22937/69. Heading ASB. Compositions for the prevention or treatment of protozoiasis (particularly coccidiosis, leucocytozoon infections, toxoplasmosis and piroplasmosis) in domestic animals comprise (a) 3-sulphanilamidoisoxazole (3-SI), a pharmaceutically acceptable salt such as an alkali metal e.g. Na or K salt thereof or a mixture of 3-SI and its salt and a physiologically acceptable carrier therefor. The compositions may also comprise (b) a pharmaceutically acceptable salt of a pyrimidine derivative of the formula (I) or (II) or a mixture thereof: wherein the formula (I) represents the monosalt and (II) the di-salt, wherein X represents a pharmaceutically acceptable acid anion, A is -S- or -CH=CH-, R<SP>1</SP> is a C 1-3 alkyl and each of R<SP>2</SP>, R<SP>3</SP> and R<SP>4</SP> is H or C 1-3 alkyl. Preferably the amount of ingredient (a) is from 0.0005 to 0.3% by weight in terms of 3-sulphanilamidoisoxazole and the amount of ingredient (b) is from 0.001 to 0.05% by weight in terms of the pyrimidine derivative base relative to the composition. The compositions may be administered in the form of powders, granules, tablets, capsules, oil and aqueous solutions, emulsions, suspensions and premixes may be incorporated in the feed or drinking water. The pyrimidine derivative may be a 3-(2-methyl, ethyl or n-propyl-4-amino-5-pyrimidinylmethyl)-4, 5-dimethylthiazolium salt such as the nitrate, hydrochloride, hydrobromide and thiocyanate mono- and di-salts. The compositions may also contain vitamins (e.g. vitamin B 2 or fat-soluble vitamins), minerals, amino acids; proteins, carbohydrates, fats, preservatives, germicides, enzyme preparations, enterostomachics, antipyretics, sedatives, antiphlogistics and purgatives.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3017068 | 1968-05-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1265536A true GB1265536A (en) | 1972-03-01 |
Family
ID=12296264
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1265536D Expired GB1265536A (en) | 1968-05-06 | 1969-05-06 |
Country Status (5)
Country | Link |
---|---|
CA (1) | CA918564A (en) |
DE (1) | DE1922672A1 (en) |
FR (1) | FR2007903B1 (en) |
GB (1) | GB1265536A (en) |
NL (1) | NL156601B (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES330619A1 (en) * | 1965-09-02 | 1967-09-16 | Sankyo Co | Improvements in the preparation of compositions to combat avichous diseases. (Machine-translation by Google Translate, not legally binding) |
IL27378A (en) * | 1966-02-15 | 1970-07-19 | Hoffmann La Roche | Poultry feed |
-
1969
- 1969-05-03 DE DE19691922672 patent/DE1922672A1/en active Pending
- 1969-05-05 NL NL6906835A patent/NL156601B/en not_active IP Right Cessation
- 1969-05-05 FR FR6914303A patent/FR2007903B1/fr not_active Expired
- 1969-05-06 CA CA050670A patent/CA918564A/en not_active Expired
- 1969-05-06 GB GB1265536D patent/GB1265536A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2007903A1 (en) | 1970-01-16 |
NL156601B (en) | 1978-05-16 |
FR2007903B1 (en) | 1974-07-12 |
NL6906835A (en) | 1969-11-10 |
CA918564A (en) | 1973-01-09 |
DE1922672A1 (en) | 1970-03-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |