GB1251976A - - Google Patents
Info
- Publication number
- GB1251976A GB1251976A GB1251976DA GB1251976A GB 1251976 A GB1251976 A GB 1251976A GB 1251976D A GB1251976D A GB 1251976DA GB 1251976 A GB1251976 A GB 1251976A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- oleanolic acid
- esterification
- aug
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 4
- MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical class C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 abstract 3
- JKLISIRFYWXLQG-UHFFFAOYSA-N Epioleonolsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4CCC3C21C JKLISIRFYWXLQG-UHFFFAOYSA-N 0.000 abstract 2
- YBRJHZPWOMJYKQ-UHFFFAOYSA-N Oleanolic acid Natural products CC1(C)CC2C3=CCC4C5(C)CCC(O)C(C)(C)C5CCC4(C)C3(C)CCC2(C1)C(=O)O YBRJHZPWOMJYKQ-UHFFFAOYSA-N 0.000 abstract 2
- MIJYXULNPSFWEK-UHFFFAOYSA-N Oleanolinsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MIJYXULNPSFWEK-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 238000005886 esterification reaction Methods 0.000 abstract 2
- 229940100243 oleanolic acid Drugs 0.000 abstract 2
- HZLWUYJLOIAQFC-UHFFFAOYSA-N prosapogenin PS-A Natural products C12CC(C)(C)CCC2(C(O)=O)CCC(C2(CCC3C4(C)C)C)(C)C1=CCC2C3(C)CCC4OC1OCC(O)C(O)C1O HZLWUYJLOIAQFC-UHFFFAOYSA-N 0.000 abstract 2
- JSCUZAYKVZXKQE-JXMROGBWSA-N (2e)-1-bromo-3,7-dimethylocta-2,6-diene Chemical compound CC(C)=CCC\C(C)=C\CBr JSCUZAYKVZXKQE-JXMROGBWSA-N 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 125000002350 geranyl group Chemical group [H]C([*])([H])/C([H])=C(C([H])([H])[H])/C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 229940071203 oleanolate Drugs 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3802468 | 1968-08-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1251976A true GB1251976A (enrdf_load_stackoverflow) | 1971-11-03 |
Family
ID=10400671
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1251976D Expired GB1251976A (enrdf_load_stackoverflow) | 1968-08-08 | 1968-08-08 |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS4815293B1 (enrdf_load_stackoverflow) |
| CH (1) | CH516546A (enrdf_load_stackoverflow) |
| ES (1) | ES370227A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1251976A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU569840B2 (en) * | 1982-04-27 | 1988-02-25 | Noristan Ltd. | Use of oleanolic acid for ulcer treatment |
-
1968
- 1968-08-08 GB GB1251976D patent/GB1251976A/en not_active Expired
-
1969
- 1969-08-04 ES ES370227A patent/ES370227A1/es not_active Expired
- 1969-08-08 JP JP6258569A patent/JPS4815293B1/ja active Pending
- 1969-08-08 CH CH1203469A patent/CH516546A/de not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU569840B2 (en) * | 1982-04-27 | 1988-02-25 | Noristan Ltd. | Use of oleanolic acid for ulcer treatment |
| US4752606A (en) * | 1982-04-27 | 1988-06-21 | 501 Noristan Limited | Pharmaceutical compositions and preparations thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4815293B1 (enrdf_load_stackoverflow) | 1973-05-14 |
| ES370227A1 (es) | 1971-04-01 |
| CH516546A (de) | 1971-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |