GB1246489A - Antibiotic compositions - Google Patents

Antibiotic compositions

Info

Publication number
GB1246489A
GB1246489A GB42214/68A GB4221468A GB1246489A GB 1246489 A GB1246489 A GB 1246489A GB 42214/68 A GB42214/68 A GB 42214/68A GB 4221468 A GB4221468 A GB 4221468A GB 1246489 A GB1246489 A GB 1246489A
Authority
GB
United Kingdom
Prior art keywords
coated
particles
sept
antibiotic
antibiotic compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB42214/68A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB1246489A publication Critical patent/GB1246489A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Abstract

1,246,489. Coated antibiotics. BRISTOLMYERS CO. 5 Sept., 1968 [5 Sept., 1967; 2 Nov., 1967 (2)], No. 42214/68. Heading A5B. Particles of ampicillin, hetacillin, nafcillin, oxacillin, cloxacillin, dicloxacillin, flucloxacillin and mixtures thereof are coated with ethyl cellulose and a wax, the product having a particle size not greater than 40 mesh (U.S.S.S.). They may be prepared by suspending the antibiotic particles in a solution of the coating materials in a volatile solvent and spray-drying. The coated particles may be incorporated into solid and liquid pharmaceutical forms. A preferred embodiment is an aqueous suspension also comprising kaolin or colloidal magnesium aluminium silicate.
GB42214/68A 1964-05-20 1968-09-05 Antibiotic compositions Expired GB1246489A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US36899164A 1964-05-20 1964-05-20
US66529767A 1967-09-05 1967-09-05
US68000867A 1967-11-02 1967-11-02
US67998267A 1967-11-02 1967-11-02

Publications (1)

Publication Number Publication Date
GB1246489A true GB1246489A (en) 1971-09-15

Family

ID=31950768

Family Applications (1)

Application Number Title Priority Date Filing Date
GB42214/68A Expired GB1246489A (en) 1964-05-20 1968-09-05 Antibiotic compositions

Country Status (11)

Country Link
BE (1) BE719923A (en)
DE (1) DE1792365A1 (en)
DK (1) DK125623B (en)
FI (1) FI48039C (en)
FR (1) FR1605499A (en)
GB (1) GB1246489A (en)
IE (1) IE32916B1 (en)
IL (1) IL30627A (en)
NL (1) NL141779B (en)
NO (1) NO126299B (en)
SE (1) SE363974B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005018617A1 (en) 2003-08-19 2005-03-03 Wyeth Fast dissolving tablet

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1532993A (en) * 1975-03-07 1978-11-22 Beecham Group Ltd Injectable antibiotic compositions
GB1598458A (en) * 1977-04-01 1981-09-23 Hoechst Uk Ltd Tableting of microcapsules

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005018617A1 (en) 2003-08-19 2005-03-03 Wyeth Fast dissolving tablet
EP1660050A1 (en) * 2003-08-19 2006-05-31 Wyeth Fast dissolving tablet
EP1660050A4 (en) * 2003-08-19 2008-09-03 Wyeth Corp Fast dissolving tablet

Also Published As

Publication number Publication date
FI48039C (en) 1974-06-10
NL141779B (en) 1974-04-16
IE32916L (en) 1969-05-02
NO126299B (en) 1973-01-22
SE363974B (en) 1974-02-11
FR1605499A (en) 1977-06-24
DE1792365A1 (en) 1972-03-09
NL6812651A (en) 1969-03-07
FI48039B (en) 1974-02-28
IL30627A0 (en) 1968-10-24
BE719923A (en) 1969-02-24
DK125623B (en) 1973-03-19
IL30627A (en) 1973-02-28
IE32916B1 (en) 1974-01-23

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