GB1236226A - Cyclopentyl-alkanoic acids and process for their manufacture - Google Patents
Cyclopentyl-alkanoic acids and process for their manufactureInfo
- Publication number
- GB1236226A GB1236226A GB23896/68A GB2389668A GB1236226A GB 1236226 A GB1236226 A GB 1236226A GB 23896/68 A GB23896/68 A GB 23896/68A GB 2389668 A GB2389668 A GB 2389668A GB 1236226 A GB1236226 A GB 1236226A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- alkyl
- ester
- phenyl
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 150000007513 acids Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000002148 esters Chemical class 0.000 abstract 8
- 150000003839 salts Chemical class 0.000 abstract 7
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 4
- 150000002923 oximes Chemical class 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000002170 ethers Chemical class 0.000 abstract 2
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- HUHXLHLWASNVDB-UHFFFAOYSA-N 2-(oxan-2-yloxy)oxane Chemical compound O1CCCCC1OC1OCCCC1 HUHXLHLWASNVDB-UHFFFAOYSA-N 0.000 abstract 1
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- -1 ester salt Chemical class 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 238000006266 etherification reaction Methods 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 125000006501 nitrophenyl group Chemical group 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64037467A | 1967-05-22 | 1967-05-22 | |
| US70453368A | 1968-02-12 | 1968-02-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1236226A true GB1236226A (en) | 1971-06-23 |
Family
ID=27093548
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB23896/68A Expired GB1236226A (en) | 1967-05-22 | 1968-05-20 | Cyclopentyl-alkanoic acids and process for their manufacture |
| GB50088/69A Expired GB1236227A (en) | 1967-05-22 | 1968-05-20 | Cyclopentyl-alkanoic acid derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB50088/69A Expired GB1236227A (en) | 1967-05-22 | 1968-05-20 | Cyclopentyl-alkanoic acid derivatives |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US3538120A (https=) |
| BE (1) | BE715492A (https=) |
| CA (1) | CA926412A (https=) |
| CH (1) | CH505774A (https=) |
| DE (1) | DE1768434A1 (https=) |
| FR (1) | FR1563495A (https=) |
| GB (2) | GB1236226A (https=) |
| NL (1) | NL6807186A (https=) |
| SE (1) | SE363625B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5114505B1 (https=) * | 1970-04-15 | 1976-05-10 | ||
| US3932467A (en) * | 1971-10-08 | 1976-01-13 | G. D. Searle & Co. | Process for the production of 2β-formyl 3α-protected hydroxy-5-oxocyclopentane-1α-heptanoic acids and esters corresponding |
| SE415756B (sv) * | 1972-06-02 | 1980-10-27 | Pfizer | Forfarande for framstellning av vissa 18-oxa- och 19-oxa-prostaglandiner |
| US4737590A (en) * | 1973-04-27 | 1988-04-12 | American Cyanamid Company | Novel 2-substituted-3,4-epoxycyclopentan-1-ones, 2-substituted-3,4-epoxycyclopentan-1-ols, and various 2-substituted-cyclopentenones |
| KR20010042285A (ko) * | 1998-03-31 | 2001-05-25 | 데이비드 엠 모이어 | Ｆｐ 작동제로서 유용한 ｃ11 옥시밀 및 히드록실아미노프로스타글란딘 |
| JP4834224B2 (ja) | 1999-03-05 | 2011-12-14 | デューク ユニバーシティ | Ｃ１６不飽和ｆｐ−選択的プロスタグランジン類縁体 |
| US20020172693A1 (en) | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
| US20020037914A1 (en) | 2000-03-31 | 2002-03-28 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
| US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
| US8722739B2 (en) | 2008-10-29 | 2014-05-13 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
| US8623918B2 (en) | 2008-10-29 | 2014-01-07 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
| CN114058007B (zh) * | 2021-11-22 | 2022-10-25 | 华南理工大学 | 一种有机碱催化炔羧酸聚合制备聚羰基烯醇酯类化合物的方法 |
-
1967
- 1967-05-22 US US640374A patent/US3538120A/en not_active Expired - Lifetime
-
1968
- 1968-02-12 US US704533A patent/US3532721A/en not_active Expired - Lifetime
- 1968-04-29 SE SE05795/68A patent/SE363625B/xx unknown
- 1968-05-08 CH CH686668A patent/CH505774A/de not_active IP Right Cessation
- 1968-05-14 CA CA019943A patent/CA926412A/en not_active Expired
- 1968-05-14 DE DE19681768434 patent/DE1768434A1/de active Pending
- 1968-05-17 FR FR1563495D patent/FR1563495A/fr not_active Expired
- 1968-05-20 GB GB23896/68A patent/GB1236226A/en not_active Expired
- 1968-05-20 GB GB50088/69A patent/GB1236227A/en not_active Expired
- 1968-05-21 BE BE715492D patent/BE715492A/xx unknown
- 1968-05-21 NL NL6807186A patent/NL6807186A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1236227A (en) | 1971-06-23 |
| CA926412A (en) | 1973-05-15 |
| US3538120A (en) | 1970-11-03 |
| US3532721A (en) | 1970-10-06 |
| NL6807186A (https=) | 1968-11-25 |
| FR1563495A (https=) | 1969-04-11 |
| BE715492A (https=) | 1968-11-21 |
| SE363625B (https=) | 1974-01-28 |
| CH505774A (de) | 1971-04-15 |
| DE1768434A1 (de) | 1971-07-01 |
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